Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Elisa Guma"'
Autor:
Elisa Guma, Antoine Beauchamp, Siyuan Liu, Elizabeth Levitis, Jacob Ellegood, Linh Pham, Rogier B Mars, Armin Raznahan, Jason P Lerch
Publikováno v:
eLife, Vol 13 (2024)
In vivo neuroimaging studies have established several reproducible volumetric sex differences in the human brain, but the causes of such differences are hard to parse. While mouse models are useful for understanding the cellular and mechanistic bases
Externí odkaz:
https://doaj.org/article/d7000913fd3948719eb239645e706653
Publikováno v:
Biology of Sex Differences, Vol 13, Iss 1, Pp 1-21 (2022)
Highlights Recent large-scale studies have reached different conclusions regarding the presence of sex differences in human neuroanatomy. We show that these contradictory findings are explained by different methodological choices. While multiple larg
Externí odkaz:
https://doaj.org/article/7183fea75be84e3898f2bd5a0eaa73c9
Autor:
Vanessa Valiquette, Elisa Guma, Lani Cupo, Daniel Gallino, Chloe Anastassiadis, Emily Snook, Gabriel A. Devenyi, M. Mallar Chakravarty
Publikováno v:
NeuroImage, Vol 269, Iss , Pp 119888- (2023)
Our current understanding of litter variability in neurodevelopmental studies using mice may limit translation of neuroscientific findings. Higher variance of measures across litters than within, often termed intra-litter likeness, may be attributabl
Externí odkaz:
https://doaj.org/article/b91bf1b29ef143e1946bbad5bf46d0eb
Autor:
Jill Rocchetti, Caroline Fasano, Gregory Dal-Bo, Elisa Guma, Salah El Mestikawy, Tak-Pan Wong, Gohar Fakhfouri, Bruno Giros
Publikováno v:
PLoS ONE, Vol 18, Iss 8, p e0289770 (2023)
Evidence suggests that subcortical hyperdopaminergia alters cognitive function in schizophrenia and antipsychotic drugs (APD) fail at rescuing cognitive deficits in patients. In a previous study, we showed that blocking D2 dopamine receptors (D2R), a
Externí odkaz:
https://doaj.org/article/e5939b5f668948ee879005b81439a6ea
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-19 (2021)
Abstract Acute exposure to cannabis has been associated with an array of cognitive alterations, increased risk for neuropsychiatric illness, and other neuropsychiatric sequelae including the emergence of acute psychotic symptoms. However, the brain a
Externí odkaz:
https://doaj.org/article/dea87ea060c54912a31281332d7c49b9
Autor:
Elsa Isingrini, Chloé Guinaudie, Léa Perret, Elisa Guma, Victor Gorgievski, Ian D. Blum, Jessica Colby-Milley, Maryia Bairachnaya, Sébastien Mella, Antoine Adamantidis, Kai-Florian Storch, Bruno Giros
Publikováno v:
Biomolecules, Vol 13, Iss 3, p 511 (2023)
Noradrenaline (NE) plays an integral role in shaping behavioral outcomes including anxiety/depression, fear, learning and memory, attention and shifting behavior, sleep-wake state, pain, and addiction. However, it is unclear whether dysregulation of
Externí odkaz:
https://doaj.org/article/ee60b9187b484d7299537af91eaf607c
Autor:
Elisa Guma, Emily Snook, Shoshana Spring, Jason P. Lerch, Brian J. Nieman, Gabriel A. Devenyi, M. Mallar Chakravarty
Publikováno v:
NeuroImage: Clinical, Vol 32, Iss , Pp 102868- (2021)
Prenatal exposure to maternal immune activation (MIA) is a risk factor for a variety of neurodevelopmental and psychiatric disorders. The timing of MIA-exposure has been shown to affect adolescent and adult offspring neurodevelopment, however, less i
Externí odkaz:
https://doaj.org/article/07e124d91a5848289b88f45d5e293cc3
Autor:
Elisa Guma, Gabriel A. Devenyi, Ashok Malla, Jai Shah, M. Mallar Chakravarty, Marita Pruessner
Publikováno v:
Frontiers in Psychiatry, Vol 8 (2017)
Sex differences have been widely observed in clinical presentation, functional outcome and neuroanatomy in individuals with a first-episode of psychosis, and chronic patients suffering from schizophrenia. However, little is known about sex difference
Externí odkaz:
https://doaj.org/article/2e2050b763cb46bb857e65d9a3c68f26
A Cross-Species Neuroimaging Study of Sex Chromosome Dosage Effects on Human and Mouse Brain Anatomy
Autor:
Elisa Guma, Antoine Beauchamp, Siyuan Liu, Elizabeth Levitis, Liv S. Clasen, Erin Torres, Jonathan Blumenthal, Francois Lalonde, Lily R. Qiu, Haley Hrncir, Allan MacKenzie-Graham, Xia Yang, Arthur P. Arnold, Jason P. Lerch, Armin Raznahan
Publikováno v:
The Journal of Neuroscience. 43:1321-1333
All eutherian mammals show chromosomal sex determination with contrasting sex chromosome dosages (SCDs) between males (XY) and females (XX). Studies in transgenic mice and humans with sex chromosome trisomy (SCT) have revealed direct SCD effects on r
Autor:
Jeremy J. Watts, Elisa Guma, Sofia Chavez, Rachel F. Tyndale, Ruth A. Ross, Sylvain Houle, Alan A. Wilson, Mallar Chakravarty, Pablo M. Rusjan, Romina Mizrahi
Publikováno v:
Neuropsychopharmacology. 47:1984-1991