Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Elisa C. Toffoli"'
Autor:
Maurice J. D. L. van der Vorst, Elisabeth C. W. Neefjes, Elisa C. Toffoli, Jolanda E. W. Oosterling-Jansen, Marije R. Vergeer, C. René Leemans, Menno P. Kooistra, Jens Voortman, Henk M. W. Verheul
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-10 (2019)
Abstract Background Three-weekly high-dose cisplatin (100 mg/m2) is considered the standard systemic regimen given concurrently with postoperative or definitive radiotherapy in locally advanced squamous cell carcinoma of the head and neck (LA-SCCHN).
Externí odkaz:
https://doaj.org/article/b776777790a94a63b3db3d151c082512
Autor:
Elisa C. Toffoli, Maike G. Sweegers, Hetty J. Bontkes, Teatske M. Altenburg, Henk M.W. Verheul, Hans J. van derVliet, Tanja D. deGruijl, Laurien M. Buffart
Publikováno v:
Physiological Reports, Vol 9, Iss 11, Pp n/a-n/a (2021)
Abstract Natural killer (NK) cells are a population of innate immune cells known to play a pivotal role against tumor spread. In multiple murine models, it was shown that physical exercise had the potential to increase NK cell antitumor activity thro
Externí odkaz:
https://doaj.org/article/30f861b3049c43bbb8fa09bf6f64221a
Autor:
Elisa C. Toffoli, Abdolkarim Sheikhi, Roeland Lameris, Lisa A. King, Amanda van Vliet, Bruce Walcheck, Henk M. W. Verheul, Jan Spanholtz, Jurriaan Tuynman, Tanja D. de Gruijl, Hans J. van der Vliet
Publikováno v:
Cancers, Vol 13, Iss 21, p 5446 (2021)
The ability to kill tumor cells while maintaining an acceptable safety profile makes Natural Killer (NK) cells promising assets for cancer therapy. Strategies to enhance the preferential accumulation and activation of NK cells in the tumor microenvir
Externí odkaz:
https://doaj.org/article/1660bc09e044423aabcf4544536051f8
Autor:
Elisa C. Toffoli, Abdolkarim Sheikhi, Yannick D. Höppner, Pita de Kok, Mahsa Yazdanpanah-Samani, Jan Spanholtz, Henk M. W. Verheul, Hans J. van der Vliet, Tanja D. de Gruijl
Publikováno v:
Cancers, Vol 13, Iss 4, p 711 (2021)
Natural Killer (NK) cells are innate immune cells with the unique ability to recognize and kill virus-infected and cancer cells without prior immune sensitization. Due to their expression of the Fc receptor CD16, effector NK cells can kill tumor cell
Externí odkaz:
https://doaj.org/article/0cafc880192e489383cdda1dcd6eed04
Autor:
Tanja D de Gruijl, Jurriaan Tuynman, Jan Spanholtz, Hans J van der Vliet, Elisa C Toffoli, Amanda A van Vliet, Henk W M Verheul
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 12 (2023)
Introduction Natural killer (NK) cells are innate lymphocytes with a key role in the defense against tumors. Recently, allogeneic NK cell-based therapies have gained interest because of their ability to directly lyse tumor cells without inducing graf
Externí odkaz:
https://doaj.org/article/fb317fc654cf49d78d04ecfc9bd6d9e7
Autor:
Suzan Vrijaldenhoven, Saskia Brouwer, Johannes Berkhof, Elisa C. Toffoli, Maurice J. D. L. van der Vorst, Theo van Voorthuizen, Henk M.W. Verheul, Myra E. van Linde, Marlien Beusink, Johan C Berends, Annette A. van Zweeden
Publikováno v:
van der Vorst, M J D L, Toffoli, E C, Beusink, M, van Linde, M E, van Voorthuizen, T, Brouwer, S, van Zweeden, A A, Vrijaldenhoven, S, Berends, J C, Berkhof, J & Verheul, H M W 2021, ' Metoclopramide, Dexamethasone, or Palonosetron for Prevention of Delayed Chemotherapy-Induced Nausea and Vomiting After Moderately Emetogenic Chemotherapy (MEDEA) : A Randomized, Phase III, Noninferiority Trial ', The Oncologist, vol. 26, no. 1, pp. e173-e181 . https://doi.org/10.1634/theoncologist.2020-0305
The Oncologist, 26(1), e173-e181. AlphaMed Press
Oncologist, 26, 1, pp. e173-e181
The Oncologist
Oncologist, 26, e173-e181
Oncologist, 26(1), E173-E181. AlphaMed Press
The Oncologist, 26(1), e173-e181. AlphaMed Press
Oncologist, 26, 1, pp. e173-e181
The Oncologist
Oncologist, 26, e173-e181
Oncologist, 26(1), E173-E181. AlphaMed Press
Background For the prevention of chemotherapy‐induced nausea and vomiting (CINV) during the delayed phase (24–120 hours) after moderately emetogenic chemotherapy (MEC), the use of 3‐day dexamethasone (DEX) is often recommended. This study compa
Autor:
Hans van Vliet, Tanja D. de Gruijl, Henk M.W. Verheul, Lisa A. King, Roeland Lameris, Abdolkarim Sheikhi, Bruce Walcheck, Elisa C. Toffoli, Jan Spanholtz, Jurriaan B. Tuynman, Amanda A. van Vliet
Publikováno v:
Cancers
Volume 13
Issue 21
Toffoli, E C, Sheikhi, A, Lameris, R, King, L A, van Vliet, A, Walcheck, B, Verheul, H M W, Spanholtz, J, Tuynman, J, de Gruijl, T D & van der Vliet, H J 2021, ' Enhancement of nk cell antitumor effector functions using a bispecific single domain antibody targeting cd16 and the epidermal growth factor receptor ', Cancers, vol. 13, no. 21, 5446 . https://doi.org/10.3390/cancers13215446
Cancers, Vol 13, Iss 5446, p 5446 (2021)
Cancers, 13(21):5446. Multidisciplinary Digital Publishing Institute (MDPI)
Cancers, 13
Cancers, 13, 21
Volume 13
Issue 21
Toffoli, E C, Sheikhi, A, Lameris, R, King, L A, van Vliet, A, Walcheck, B, Verheul, H M W, Spanholtz, J, Tuynman, J, de Gruijl, T D & van der Vliet, H J 2021, ' Enhancement of nk cell antitumor effector functions using a bispecific single domain antibody targeting cd16 and the epidermal growth factor receptor ', Cancers, vol. 13, no. 21, 5446 . https://doi.org/10.3390/cancers13215446
Cancers, Vol 13, Iss 5446, p 5446 (2021)
Cancers, 13(21):5446. Multidisciplinary Digital Publishing Institute (MDPI)
Cancers, 13
Cancers, 13, 21
Simple Summary Strategies to enhance the preferential accumulation and activation of Natural Killer (NK) cells in the tumor microenvironment can be expected to increase the efficacy of NK cell-based cancer immunotherapy. In this study, we report that
Autor:
Anneleen Van Hout, Alex Klarenbeek, Hans de Haard, Tom Van Loy, Raimond Heukers, Elisa C. Toffoli, Dominique Schols, Martine J. Smit, Jordi Doijen, Aurélien Zarca, Vladimir Bobkov, Hans J. van der Vliet, Bas van der Woning, Marta Arimont, Magdalena Bialkowska
Publikováno v:
Biochemical Pharmacology, 158, 413-424. Elsevier Inc.
Bobkov, V, Zarca, A M, van Hout, A, Arimont, M, Doijen, J, Bialkowska, M, Toffoli, E, Klarenbeek, A, van der Woning, B, van der Vliet, H J, van Loy, T, de Haard, H, Schols, D, Heukers, R & Smit, M J 2018, ' Nanobody-Fc constructs targeting chemokine receptor CXCR4 potently inhibit signaling and CXCR4-mediated HIV-entry and induce antibody effector functions ', Biochemical Pharmacology, vol. 158, pp. 413-424 . https://doi.org/10.1016/j.bcp.2018.10.014
Biochemical Pharmacology
Bobkov, V, Zarca, A M, Van Hout, A, Arimont, M, Doijen, J, Bialkowska, M, Toffoli, E, Klarenbeek, A, van der Woning, B, van der Vliet, H J, Van Loy, T, de Haard, H, Schols, D, Heukers, R & Smit, M J 2018, ' Nanobody-Fc constructs targeting chemokine receptor CXCR4 potently inhibit signaling and CXCR4-mediated HIV-entry and induce antibody effector functions ', Biochemical Pharmacology, vol. 158, pp. 413-424 . https://doi.org/10.1016/j.bcp.2018.10.014
Bobkov, V, Zarca, A M, van Hout, A, Arimont, M, Doijen, J, Bialkowska, M, Toffoli, E, Klarenbeek, A, van der Woning, B, van der Vliet, H J, van Loy, T, de Haard, H, Schols, D, Heukers, R & Smit, M J 2018, ' Nanobody-Fc constructs targeting chemokine receptor CXCR4 potently inhibit signaling and CXCR4-mediated HIV-entry and induce antibody effector functions ', Biochemical Pharmacology, vol. 158, pp. 413-424 . https://doi.org/10.1016/j.bcp.2018.10.014
Biochemical Pharmacology
Bobkov, V, Zarca, A M, Van Hout, A, Arimont, M, Doijen, J, Bialkowska, M, Toffoli, E, Klarenbeek, A, van der Woning, B, van der Vliet, H J, Van Loy, T, de Haard, H, Schols, D, Heukers, R & Smit, M J 2018, ' Nanobody-Fc constructs targeting chemokine receptor CXCR4 potently inhibit signaling and CXCR4-mediated HIV-entry and induce antibody effector functions ', Biochemical Pharmacology, vol. 158, pp. 413-424 . https://doi.org/10.1016/j.bcp.2018.10.014
Upregulation of the chemokine receptor CXCR4 contributes to the progression and metastasis of both solid and hematological malignancies, rendering this receptor an attractive therapeutic target. Besides the only FDA-approved CXCR4 antagonist Plerixaf
Autor:
Maike G. Sweegers, Elisa C. Toffoli, Teatske M. Altenburg, Tanja D. de Gruijl, Hetty J. Bontkes, Henk M.W. Verheul, Hans van Vliet, Laurien M. Buffart
Publikováno v:
Physiological Reports, 9
Physiological Reports, 9(11):e14919. John Wiley and Sons Inc.
Physiological Reports
Physiological Reports, 9, 11
Toffoli, E C, Sweegers, M G, Bontkes, H J, Altenburg, T M, Verheul, H M W, van der Vliet, H J, de Gruijl, T D & Buffart, L M 2021, ' Effects of physical exercise on natural killer cell activity during (neo)adjuvant chemotherapy : A randomized pilot study ', Physiological Reports, vol. 9, no. 11, e14919, pp. e14919 . https://doi.org/10.14814/phy2.14919
Physiological Reports, Vol 9, Iss 11, Pp n/a-n/a (2021)
Physiological Reports, 9(11):e14919. John Wiley and Sons Inc.
Physiological Reports
Physiological Reports, 9, 11
Toffoli, E C, Sweegers, M G, Bontkes, H J, Altenburg, T M, Verheul, H M W, van der Vliet, H J, de Gruijl, T D & Buffart, L M 2021, ' Effects of physical exercise on natural killer cell activity during (neo)adjuvant chemotherapy : A randomized pilot study ', Physiological Reports, vol. 9, no. 11, e14919, pp. e14919 . https://doi.org/10.14814/phy2.14919
Physiological Reports, Vol 9, Iss 11, Pp n/a-n/a (2021)
Natural killer (NK) cells are a population of innate immune cells known to play a pivotal role against tumor spread. In multiple murine models, it was shown that physical exercise had the potential to increase NK cell antitumor activity through their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::758d2c61e939e1e565c46ffbec5cb131
http://hdl.handle.net/2066/235002
http://hdl.handle.net/2066/235002
Autor:
Hans van Vliet, Pita de Kok, Mahsa Yazdanpanah-Samani, Yannick D. Höppner, Abdolkarim Sheikhi, Henk M.W. Verheul, Jan Spanholtz, Elisa C. Toffoli, Tanja D. de Gruijl
Publikováno v:
Toffoli, E C, Sheikhi, A, Höppner, Y D, de Kok, P, Yazdanpanah-Samani, M, Spanholtz, J, Verheul, H M W, van der Vliet, H J & de Gruijl, T D 2021, ' Natural killer cells and anti-cancer therapies : Reciprocal effects on immune function and therapeutic response ', Cancers, vol. 13, no. 4, 711, pp. 1-27 . https://doi.org/10.3390/cancers13040711
Cancers
Cancers, 13, 4
Cancers, Vol 13, Iss 711, p 711 (2021)
Cancers, 13
Cancers
Cancers, 13, 4
Cancers, Vol 13, Iss 711, p 711 (2021)
Cancers, 13
Simple Summary Natural Killer (NK) cells are innate lymphocytes that play an important role in the immune response against cancer. Their activity is controlled by a balance of inhibitory and activating receptors, which in cancer can be skewed to favo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4155f63557a4bd14e24d31b33f90b38a
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/232069
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/232069