Výsledky vyhledávání - "Elisa Bordón"

Radio-induced apoptosis of peripheral blood CD8 T lymphocytes is a novel prognostic factor for survival in cervical carcinoma patients

Autor: Beatriz Pinar, Pedro C. Lara, A. Valenciano, Mario Federico, Elisa Bordón, R. Ordoñez, Marta Lloret, Carlos Rodríguez-Gallego, Luis Alberto Henríquez-Hernández

Publikováno v: Strahlentherapie und Onkologie. 190:210-216

A close relationship exists between immune response and tumor behavior. This study aimed to explore the associations between radiation-induced apoptosis (RIA) in peripheral blood lymphocytes (PBL) and clinical pathological variables. Furthermore, it

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3d5fb3b77cc2c008f164eb030dd1601
https://doi.org/10.1007/s00066-013-0488-x

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Common genomic signaling among initial DNA damage and radiation-induced apoptosis in peripheral blood lymphocytes from locally advanced breast cancer patients

Autor: Elisa Bordón, Luis Alberto Henríquez-Hernández, Pedro C. Lara, Beatriz Pinar, Ruth Carmona-Vigo, Amilcar Flores-Morales, Carlos Rodríguez-Gallego

Publikováno v: The Breast. 22:28-33

Purpose To investigate the genomic signaling that defines sensitive lymphocytes to radiation and if such molecular profiles are consistent with clinical toxicity; trying to disclose the radiobiology mechanisms behind these cellular processes. Patient

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2f49eb863a71cb9d85c5f0eed0a2d75e
https://doi.org/10.1016/j.breast.2012.05.005

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Prediction of normal tissue toxicity as part of the individualized treatment with radiotherapy in oncology patients

Autor: Luis Alberto Henríquez-Hernández, Elisa Bordón, Carlos Rodríguez-Gallego, Pedro C. Lara, Beatriz Pinar, Marta Lloret

Publikováno v: Surgical Oncology. 21:201-206

Normal tissue toxicity caused by radiotherapy conditions the success of the treatment and the quality of life of patients. Radiotherapy is combined with surgery in both the preoperative or postoperative setting for the treatment of most localized sol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::142bf90f576430c73d979b2171071a7a
https://doi.org/10.1016/j.suronc.2011.12.002

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BCL-2, in combination with MVP and IGF-1R expression, improves prediction of clinical outcome in complete response cervical carcinoma patients treated by radiochemotherapy

Autor: Pedro C. Lara, Luis Alberto Henríquez-Hernández, Beatriz Pinar, Amina Lubrano, Agustin Rey, Marta Lloret, Elisa Bordón

Publikováno v: Gynecologic Oncology. 122:585-589

To investigate whether BCL-2 expression would improve MVP/IGF-1R prediction of clinical outcome in cervix carcinoma patients treated by radiochemotherapy, and suggest possible mechanisms behind this effect.Fifty consecutive patients, who achieved com

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef8c9f06379b7d5b64f420fb78b76ef5
https://doi.org/10.1016/j.ygyno.2011.05.037

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IGF-1R expression predicts clinical outcome in patients with locally advanced oral squamous cell carcinoma

Autor: Agustin Rey, Elisa Bordón, Pedro C. Lara, Mercedes Moreno, Marta Lloret, Luis Alberto Henríquez-Hernández

Publikováno v: Oral Oncology. 47:615-619

Summary To assess the expression of IGF-1R in oral cavity squamous cell carcinoma patients, to explore its relation with clinical and pathologic prognostic factors and its role in predicting clinical outcome. One hundred and thirty-one consecutive pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91b649455495442525f9d351e6e32c09
https://doi.org/10.1016/j.oraloncology.2011.05.005

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Role of CD4 and CD8 T-lymphocytes, B-lymphocytes and Natural Killer cells in the prediction of radiation-induced late toxicity in cervical cancer patients

Autor: Elisa Bordón, Pedro C. Lara, Beatriz Pinar, Carlos Rodríguez-Gallego, Marta Lloret, Luis Alberto Henríquez-Hernández

Publikováno v: International Journal of Radiation Biology. 87:424-431

To analyse the role of in vitro radio-induced apoptosis of lymphocyte subpopulations as predictive test for late effects in cervical cancer patients treated with radiotherapy.Ninety-four consecutive patients and four healthy controls were included in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::239a50adb5ddc274a0f53831fb8180c3
https://doi.org/10.3109/09553002.2010.537433

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Major Vault Protein May Affect Nonhomologous End-Joining Repair and Apoptosis Through Ku70/80 and BAX Downregulation in Cervical Carcinoma Tumors

Autor: Agustin Rey, Pedro C. Lara, Elisa Bordón, Beatriz Pinar, Fausto Fontes, Marta Lloret, Orlando Falcón

Publikováno v: International Journal of Radiation Oncology*Biology*Physics. 73:976-979

We investigated the relationship between major vault protein (MVP) expression, the nonhomologous end-joining (NHEJ) repair gene Ku70/80, and related genes involved in the regulation of apoptosis and proliferation to shed light on the possible causes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25ff70ee6fc096edb58e80411249ea82
https://doi.org/10.1016/j.ijrobp.2008.11.013

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Hypoxia downregulates Ku70/80 expression in cervical carcinoma tumors

Autor: Rosa María Cáceres Apolinario, Orlando Falcón, Elisa Bordón, Agustin Rey, Marta Lloret, Pedro C. Lara, Bernardino Clavo, Ana Ruiz Alonso, Claus Belka

Publikováno v: Radiotherapy and Oncology. 89:222-226

Hypoxia may inhibits the NHEJ DNA repair through downregulating Ku70/80 expression and combined with an increased angiogenesis and altered p53 expression would be responsible for tumor progression in cervical carcinoma.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05207e5f302fe7590402a90f1a8cb5d4
https://doi.org/10.1016/j.radonc.2008.07.018

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Radiation-Induced DNA Damage as a Predictor of Long-Term Toxicity in Locally Advanced Breast Cancer Patients Treated with High-Dose Hyperfractionated Radical Radiotherapy

Autor: Elisa Bordón, M. Villalobos, Rosa Guerrero, Pedro C. Lara, Beatriz Pinar, J M Ruiz de Almodóvar, María Isabel Núñez, Marta Lloret, Juan de Dios Luna

Publikováno v: Radiation Research. 168:415-422

This 14-year-long study makes a novel contribution to the debate on the relationship between the in vitro radiosensitivity of peripheral blood lymphocytes and normal tissue reactions after radiation therapy. The aims were (1) to prospectively assess

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eedb97cf272ba6a7c15317f89dc2ebd
https://doi.org/10.1667/rr0746.1

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IGF-1R expression in localized cervical carcinoma patients treated by radiochemotherapy

Autor: Beatriz Pinar, María A. Hernández, Agustin Rey, Marta Lloret, Pedro C. Lara, Elisa Bordón, Orlando Falcón, Fernando Molano

Publikováno v: Gynecologic Oncology. 106:8-11

Purpose To assess the expression of IGF-1R in cervix carcinoma patients treated by radiotherapy and concomitant chemotherapy, its relation to clinical and pathologic prognostic factors and its role in predicting clinical outcome. Materials and method

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06291de0d203d662f1ea7e8371cface3
https://doi.org/10.1016/j.ygyno.2007.04.004

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