Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Elisa Benedetti"'
Autor:
Elisa Benedetti, Kelsey Chetnik, Thomas Flynn, Christopher E. Barbieri, Douglas S. Scherr, Massimo Loda, Jan Krumsiek
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-8 (2023)
Abstract Prostate cancer is the second most common cancer in men and affects 1 in 9 men in the United States. Early screening for prostate cancer often involves monitoring levels of prostate-specific antigen (PSA) and performing digital rectal exams.
Externí odkaz:
https://doaj.org/article/d0a20e13995d4a0ca46dac4e068bf0ec
Autor:
Richa Batra, Rie Uni, Oleh M. Akchurin, Sergio Alvarez-Mulett, Luis G. Gómez-Escobar, Edwin Patino, Katherine L. Hoffman, Will Simmons, William Whalen, Kelsey Chetnik, Mustafa Buyukozkan, Elisa Benedetti, Karsten Suhre, Edward Schenck, Soo Jung Cho, Augustine M. K. Choi, Frank Schmidt, Mary E. Choi, Jan Krumsiek
Publikováno v:
Molecular Medicine, Vol 29, Iss 1, Pp 1-10 (2023)
Abstract Background Acute respiratory distress syndrome (ARDS), a life-threatening condition during critical illness, is a common complication of COVID-19. It can originate from various disease etiologies, including severe infections, major injury, o
Externí odkaz:
https://doaj.org/article/73b7e4f3cafd424db0c9cb48062b9e13
Autor:
Richa Batra, William Whalen, Sergio Alvarez-Mulett, Luis G. Gomez-Escobar, Katherine L. Hoffman, Will Simmons, John Harrington, Kelsey Chetnik, Mustafa Buyukozkan, Elisa Benedetti, Mary E. Choi, Karsten Suhre, Edward Schenck, Augustine M. K. Choi, Frank Schmidt, Soo Jung Cho, Jan Krumsiek
Publikováno v:
PLoS Pathogens, Vol 18, Iss 9 (2022)
Background Acute respiratory distress syndrome (ARDS), a life-threatening condition characterized by hypoxemia and poor lung compliance, is associated with high mortality. ARDS induced by COVID-19 has similar clinical presentations and pathological m
Externí odkaz:
https://doaj.org/article/045db0b9a19544b4881ea62a59729541
Autor:
Mustafa Buyukozkan, Sergio Alvarez-Mulett, Alexandra C. Racanelli, Frank Schmidt, Richa Batra, Katherine L. Hoffman, Hina Sarwath, Rudolf Engelke, Luis Gomez-Escobar, Will Simmons, Elisa Benedetti, Kelsey Chetnik, Guoan Zhang, Edward Schenck, Karsten Suhre, Justin J. Choi, Zhen Zhao, Sabrina Racine-Brzostek, He S. Yang, Mary E. Choi, Augustine M.K. Choi, Soo Jung Cho, Jan Krumsiek
Publikováno v:
iScience, Vol 25, Iss 7, Pp 104612- (2022)
Summary: The coronavirus disease-19 (COVID-19) pandemic has ravaged global healthcare with previously unseen levels of morbidity and mortality. In this study, we performed large-scale integrative multi-omics analyses of serum obtained from COVID-19 p
Externí odkaz:
https://doaj.org/article/a62f77fb3df5497ebf2ec8150d80ce78
Autor:
Elisa Benedetti, Maja Pučić-Baković, Toma Keser, Nathalie Gerstner, Mustafa Büyüközkan, Tamara Štambuk, Maurice H. J. Selman, Igor Rudan, Ozren Polašek, Caroline Hayward, Hassen Al-Amin, Karsten Suhre, Gabi Kastenmüller, Gordan Lauc, Jan Krumsiek
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Correlation network inference is typically based on the significance of the correlation coefficients, but this procedure is not guaranteed to capture biological mechanisms. Here, the authors develop a cutoff selection algorithm that maximizes the ove
Externí odkaz:
https://doaj.org/article/010a6cf3af164aa7978eb3f55d61f7d7
Publikováno v:
Metabolites, Vol 13, Iss 1, p 127 (2023)
High-dimensional omics datasets frequently contain missing data points, which typically occur due to concentrations below the limit of detection (LOD) of the profiling platform. The presence of such missing values significantly limits downstream stat
Externí odkaz:
https://doaj.org/article/01a23bdacd264387bb8f7ac2c1695bf7
Autor:
Elisa Benedetti, Maja Pučić-Baković, Toma Keser, Annika Wahl, Antti Hassinen, Jeong-Yeh Yang, Lin Liu, Irena Trbojević-Akmačić, Genadij Razdorov, Jerko Štambuk, Lucija Klarić, Ivo Ugrina, Maurice H. J. Selman, Manfred Wuhrer, Igor Rudan, Ozren Polasek, Caroline Hayward, Harald Grallert, Konstantin Strauch, Annette Peters, Thomas Meitinger, Christian Gieger, Marija Vilaj, Geert-Jan Boons, Kelley W. Moremen, Tatiana Ovchinnikova, Nicolai Bovin, Sakari Kellokumpu, Fabian J. Theis, Gordan Lauc, Jan Krumsiek
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
IgG glycosylation is an important factor in immune function, yet the molecular details of protein glycosylation remain poorly understood. The data-driven approach presented here uses large-scale plasma IgG mass spectrometry measurements to infer new
Externí odkaz:
https://doaj.org/article/11aecacd968d49ca905c6b1672c3015d
Autor:
Emanuela Colasante, Elisa Benedetti, Loredana Fortunato, Marco Scalese, Roberta Potente, Arianna Cutilli, Sabrina Molinaro
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0225140 (2019)
PurposeThe aim of this experimental study was to investigate whether paper-and-pencil and computerized surveys administered in the school setting yield equivalent data quality indicators and risk behavior prevalence estimates.MethodsData were drawn f
Externí odkaz:
https://doaj.org/article/f5da383a1b254525a0a2f3fc6e9bf451
Autor:
Elisa Benedetti, Nathalie Gerstner, Maja Pučić-Baković, Toma Keser, Karli R. Reiding, L. Renee Ruhaak, Tamara Štambuk, Maurice H.J. Selman, Igor Rudan, Ozren Polašek, Caroline Hayward, Marian Beekman, Eline Slagboom, Manfred Wuhrer, Malcolm G. Dunlop, Gordan Lauc, Jan Krumsiek
Publikováno v:
Metabolites, Vol 10, Iss 7, p 271 (2020)
Glycomics measurements, like all other high-throughput technologies, are subject to technical variation due to fluctuations in the experimental conditions. The removal of this non-biological signal from the data is referred to as normalization. Contr
Externí odkaz:
https://doaj.org/article/ef5896d2af194541bc609360dafec7a6
Autor:
Annika Wahl, Erik van den Akker, Lucija Klaric, Jerko Štambuk, Elisa Benedetti, Rosina Plomp, Genadij Razdorov, Irena Trbojević-Akmačić, Joris Deelen, Diana van Heemst, P. Eline Slagboom, Frano Vučković, Harald Grallert, Jan Krumsiek, Konstantin Strauch, Annette Peters, Thomas Meitinger, Caroline Hayward, Manfred Wuhrer, Marian Beekman, Gordan Lauc, Christian Gieger
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Immunoglobulin G (IgG), a glycoprotein secreted by plasma B-cells, plays a major role in the human adaptive immune response and are associated with a wide range of diseases. Glycosylation of the Fc binding region of IgGs, responsible for the antibody
Externí odkaz:
https://doaj.org/article/7ad2ef8175ff4d4086d23decc2cfc961