Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Elisa Araldi"'
Autor:
Uchenna Alex Anyaegbunam, Piyush More, Jean-Fred Fontaine, Vincent ten Cate, Katrin Bauer, Ute Distler, Elisa Araldi, Laura Bindila, Philipp Wild, Miguel A. Andrade-Navarro
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 12, Pp 9904-9916 (2023)
Lipids are important modifiers of protein function, particularly as parts of lipoproteins, which transport lipophilic substances and mediate cellular uptake of circulating lipids. As such, lipids are of particular interest as blood biological markers
Externí odkaz:
https://doaj.org/article/14516e95ea334d84a0d3171846200584
Autor:
Giampaolo Trivellin, Adrian F. Daly, Laura C. Hernández-Ramírez, Elisa Araldi, Christina Tatsi, Ryan K. Dale, Gus Fridell, Arjun Mittal, Fabio R. Faucz, James R. Iben, Tianwei Li, Eleonora Vitali, Stanko S. Stojilkovic, Peter Kamenicky, Chiara Villa, Bertrand Baussart, Prashant Chittiboina, Camilo Toro, William A. Gahl, Erica A. Eugster, Luciana A. Naves, Marie-Lise Jaffrain-Rea, Wouter W. de Herder, Sebastian JCMM Neggers, Patrick Petrossians, Albert Beckers, Andrea G. Lania, Richard E. Mains, Betty A. Eipper, Constantine A. Stratakis
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionPituitary adenomas (PAs) are common, usually benign tumors of the anterior pituitary gland which, for the most part, have no known genetic cause. PAs are associated with major clinical effects due to hormonal dysregulation and tumoral imp
Externí odkaz:
https://doaj.org/article/a30ad5f4cae84c6c862ca43129169b04
Autor:
Giovanna Grigolon, Elisa Araldi, Reto Erni, Jia Yee Wu, Carolin Thomas, Marco La Fortezza, Beate Laube, Doris Pöhlmann, Markus Stoffel, Kim Zarse, Erick M. Carreira, Michael Ristow, Fabian Fischer
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Life- and healthspan of organisms can be modulated by dietary, genetic, or pharmacological interventions, which often affect metabolic pathways. Here the authors report that Grainyhead 1 is an evolutionarily conserved, drug-inducible transcription fa
Externí odkaz:
https://doaj.org/article/cb59d5e7eada454092055d343fa39584
Autor:
Nathan L. Price, Abhishek K. Singh, Noemi Rotllan, Leigh Goedeke, Allison Wing, Alberto Canfrán-Duque, Alberto Diaz-Ruiz, Elisa Araldi, Ángel Baldán, Joao-Paulo Camporez, Yajaira Suárez, Matthew S. Rodeheffer, Gerald I. Shulman, Rafael de Cabo, Carlos Fernández-Hernando
Publikováno v:
Cell Reports, Vol 22, Iss 8, Pp 2133-2145 (2018)
Summary: While therapeutic modulation of miRNAs provides a promising approach for numerous diseases, the promiscuous nature of miRNAs raises concern over detrimental off-target effects. miR-33 has emerged as a likely target for treatment of cardiovas
Externí odkaz:
https://doaj.org/article/e344e7cdc5634e7db68d175d5c1581a0
Autor:
Alberto Canfrán‐Duque, Noemi Rotllan, Xinbo Zhang, Marta Fernández‐Fuertes, Cristina Ramírez‐Hidalgo, Elisa Araldi, Lidia Daimiel, Rebeca Busto, Carlos Fernández‐Hernando, Yajaira Suárez
Publikováno v:
EMBO Molecular Medicine, Vol 9, Iss 9, Pp 1244-1262 (2017)
Abstract Atherosclerosis, the major cause of cardiovascular disease, is a chronic inflammatory disease characterized by the accumulation of lipids and inflammatory cells in the artery wall. Aberrant expression of microRNAs has been implicated in the
Externí odkaz:
https://doaj.org/article/9c10e68c45eb4231aed7f8eaef9ae744
Autor:
Elisa Araldi, Marta Fernández-Fuertes, Alberto Canfrán-Duque, Wenwen Tang, Gary W. Cline, Julio Madrigal-Matute, Jordan S. Pober, Miguel A. Lasunción, Dianqing Wu, Carlos Fernández-Hernando, Yajaira Suárez
Publikováno v:
Cell Reports, Vol 19, Iss 13, Pp 2743-2755 (2017)
Macrophages perform critical functions in both innate immunity and cholesterol metabolism. Here, we report that activation of Toll-like receptor 4 (TLR4) in macrophages causes lanosterol, the first sterol intermediate in the cholesterol biosynthetic
Externí odkaz:
https://doaj.org/article/b967b084a196471a94bca71436aeadaf
Autor:
Binod Aryal, Noemi Rotllan, Elisa Araldi, Cristina M. Ramírez, Shun He, Benjamin G. Chousterman, Ashley M. Fenn, Amarylis Wanschel, Julio Madrigal-Matute, Nikhil Warrier, Jose L. Martín-Ventura, Filip K. Swirski, Yajaira Suárez, Carlos Fernández-Hernando
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Angiopoietin-like 4 protein (ANGPTL4) is a regulator of lipoprotein metabolism whose role in atherosclerosis has been controversial. Here the authors show that ANGPTL4 deficiency in haematopoietic cells increases atherogenesis by promoting myeloid pr
Externí odkaz:
https://doaj.org/article/40a361abcb9741eda09eb9b03b905155
International Society for Extracellular Vesicles: first annual meeting, April 17–21, 2012: ISEV-2012
Autor:
Elisa Araldi, Eva-Maria Krämer-Albers, Esther Nolte-‘t Hoen, Hector Peinado, Katarzyna Maria Psonka-Antonczyk, Pooja Rao, Guillaume van Niel, María Yáñez-Mó, Irina Nazarenko
Publikováno v:
Journal of Extracellular Vesicles, Vol 1, Iss 0, Pp 1-11 (2012)
Extracellular micro- and nano-scale membrane vesicles produced by different cells are recognised as an essential entity of physiological fluids in a variety of organisms and function as mediators of intercellular communication employed for the regula
Externí odkaz:
https://doaj.org/article/ec4d092990f94280a5f9a732fd293ca6
Autor:
Ashley M Miller, Derek S Gilchrist, Jagtar Nijjar, Elisa Araldi, Cristina M Ramirez, Christopher A Lavery, Carlos Fernández-Hernando, Iain B McInnes, Mariola Kurowska-Stolarska
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72324 (2013)
Hepatic steatosis is a global epidemic that is thought to contribute to the pathogenesis of type 2 diabetes. MicroRNAs (miRs) are regulators that can functionally integrate a range of metabolic and inflammatory pathways in liver. We aimed to investig
Externí odkaz:
https://doaj.org/article/8508583358914a5dae77f177289ea05d
Objective:To investigate the mortality risk linked to prescription of different anti-diabetic medication classes.Design:Prospective population-based study.Setting:UK Biobank.Participants:410 389 of the 502 536 participants in UK Biobank with covariat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf0af7b10b1c11d85c617a598aadb629
https://doi.org/10.1101/2023.05.19.23290214
https://doi.org/10.1101/2023.05.19.23290214