Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Elisa A. Liehn"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3114 (2024)
Currently, coronary artery bypass and reperfusion therapies are considered the gold standard in long-term treatments to restore heart function after acute myocardial infarction. As a drawback of these restoring strategies, reperfusion after an ischem
Externí odkaz:
https://doaj.org/article/73d51c4e10334a95b775b573b77c04b5
A neutralizing IL-11 antibody reduces vessel hyperplasia in a mouse carotid artery wire injury model
Autor:
David Schumacher, Elisa A. Liehn, Pakhwan Nilcham, David Castaño Mayan, Chutima Rattanasopa, Kaviya Anand, Gustavo E. Crespo-Avilan, Sauri Hernandez-Resendiz, Roshni R. Singaraja, Stuart A. Cook, Derek J. Hausenloy
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Vascular restenosis remains a major problem in patients with coronary artery disease (CAD) and peripheral artery disease (PAD). Neointimal hyperplasia, defined by post-procedure proliferation and migration of vascular smooth muscle cells (VS
Externí odkaz:
https://doaj.org/article/2cdabc40b84c435688af1cffde7a4c71
Autor:
Julia Wollenhaupt, Janina Frisch, Eva Harlacher, Dickson W.L. Wong, Han Jin, Corinna Schulte, Sonja Vondenhoff, Julia Moellmann, Barbara Mara Klinkhammer, Li Zhang, Adelina Baleanu-Curaj, Elisa A. Liehn, Thimoteus Speer, Andrey Kazakov, Christian Werner, Emiel P.C. van der Vorst, Simina-Ramona Selejan, Mathias Hohl, Michael Böhm, Rafael Kramann, Erik A.L. Biessen, Michael Lehrke, Nikolaus Marx, Joachim Jankowski, Christoph Maack, Peter Boor, Leticia Prates Roma, Heidi Noels
Publikováno v:
Redox Biology, Vol 56, Iss , Pp 102459- (2022)
Aims: Patients with chronic kidney disease (CKD) have an increased risk of cardiovascular events and exhibit myocardial changes including left ventricular (LV) hypertrophy and fibrosis, overall referred to as ‘uremic cardiomyopathy’. Although dif
Externí odkaz:
https://doaj.org/article/da483e5c15e143c481fbb9e3d6886c99
Autor:
David Schumacher, Adelina Curaj, Mareike Staudt, Sakine Simsekyilmaz, Isabella Kanzler, Peter Boor, Barbara Mara Klinkhammer, Xiaofeng Li, Octavian Bucur, Adnan Kaabi, Yichen Xu, Huabo Zheng, Pakhwan Nilcham, Alexander Schuh, Mihaela Rusu, Elisa A. Liehn
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 14571 (2022)
Myocardial infarction is remains the leading cause of death in developed countries. Recent data show that the composition of the extracellular matrix might differ despite similar heart function and infarction sizes. Because collagen is the main compo
Externí odkaz:
https://doaj.org/article/a63897caa4344e12802848932e34c808
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 2, p 867 (2022)
Endothelial progenitor cells (EPCs) are involved in vascular repair and modulate properties of smooth muscle cells (SMCs) relevant for their contribution to neointima formation following injury. Considering the relevant role of the CXCL12–CXCR4 axi
Externí odkaz:
https://doaj.org/article/4b40f81dcb324145a103f0d6e9df9518
Autor:
David Schumacher, Elisa A. Liehn, Anjana Singh, Adelina Curaj, Erwin Wijnands, Sergio A. Lira, Frank Tacke, Joachim Jankowski, Erik A.L. Biessen, Emiel P.C. van der Vorst
Publikováno v:
Biomedicines, Vol 9, Iss 11, p 1532 (2021)
Ischemia-reperfusion injury after the reopening of an occluded coronary artery is a major cause of cardiac damage and inflammation after acute myocardial infarction. The chemokine axis CCL20-CCR6 is a key player in various inflammatory processes, inc
Externí odkaz:
https://doaj.org/article/49aff1fc90e644ce8c2814a7984b1834
Autor:
Rodica Diaconu, Nicole Schaaps, Mamdouh Afify, Peter Boor, Anne Cornelissen, Roberta A. Florescu, Sakine Simsekyilmaz, Teddy El-Khoury, David Schumacher, Mihai Ioana, Ioana Streata, Constantin Militaru, Ionut Donoiu, Felix Vogt, Elisa A. Liehn
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 18, p 9688 (2021)
ApoE abnormality represents a well-known risk factor for cardiovascular diseases. Beyond its role in lipid metabolism, novel studies demonstrate a complex involvement of apoE in membrane homeostasis and signaling as well as in nuclear transcription.
Externí odkaz:
https://doaj.org/article/a864240947514f728b7a5ddfc1677452
Autor:
David Schumacher, Adelina Curaj, Sakine Simsekyilmaz, Andreas Schober, Elisa A. Liehn, Sebastian F. Mause
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 5480 (2021)
Myocardial infarction remains the most common cause of heart failure with adverse remodeling. MicroRNA (miR)155 is upregulated following myocardial infarction and represents a relevant regulatory factor for cardiac remodeling by engagement in cardiac
Externí odkaz:
https://doaj.org/article/e6ebb0d7083b490aa2b879d94801d02d
Autor:
David Schumacher, Adelina Curaj, Mareike Staudt, Franziska Cordes, Andreea R. Dumitraşcu, Benjamin Rolles, Christian Beckers, Josefin Soppert, Mihaela Rusu, Sakine Simsekyilmaz, Kinan Kneizeh, Chrishan J. A. Ramachandra, Derek J. Hausenloy, Elisa A. Liehn
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9, p 4401 (2021)
Phosphatidylserines are known to sustain skeletal muscle activity during intense activity or hypoxic conditions, as well as preserve neurocognitive function in older patients. Our previous studies pointed out a potential cardioprotective role of phos
Externí odkaz:
https://doaj.org/article/457c74375b58484b8ac4f0495b691f5c
Autor:
Adelina Curaj, David Schumacher, Mihaela Rusu, Mareike Staudt, Xiaofeng Li, Sakine Simsekyilmaz, Vera Jankowski, Joachim Jankowski, Andreea Ramona Dumitraşcu, Derek J Hausenloy, Alexander Schuh, Elisa A. Liehn
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 10, p 3685 (2020)
Aim: Recruitment of neutrophils to the heart following acute myocardial infarction (MI) initiates inflammation and contributes to adverse post-infarct left ventricular (LV) remodeling. However, therapeutic inhibition of neutrophil recruitment into th
Externí odkaz:
https://doaj.org/article/00ac9ac384f64541a060cc35145bcf59