Zobrazeno 1 - 10
of 144
pro vyhledávání: '"Elisa, Greggio"'
Autor:
Lucia Iannotta, Rachel Fasiczka, Giulia Favetta, Yibo Zhao, Elena Giusto, Elena Dall’Ara, Jianning Wei, Franz Y. Ho, Claudia Ciriani, Susanna Cogo, Isabella Tessari, Ciro Iaccarino, Maxime Liberelle, Luigi Bubacco, Jean-Marc Taymans, Claudia Manzoni, Arjan Kortholt, Laura Civiero, Sabine Hilfiker, Michael L. Lu, Elisa Greggio
Publikováno v:
Cell Death and Disease, Vol 15, Iss 10, Pp 1-14 (2024)
Abstract P21 activated kinase 6 (PAK6) is a serine-threonine kinase with physiological expression enriched in the brain and overexpressed in a number of human tumors. While the role of PAK6 in cancer cells has been extensively investigated, the physi
Externí odkaz:
https://doaj.org/article/795a4c0f9a0e410b87c1129fe09b26ab
Autor:
Anna Masato, Annapaola Andolfo, Giulia Favetta, Edoardo Niccolò Bellini, Susanna Cogo, Luisa Dalla Valle, Daniela Boassa, Elisa Greggio, Nicoletta Plotegher, Luigi Bubacco
Publikováno v:
Cell Death and Disease, Vol 15, Iss 6, Pp 1-18 (2024)
Abstract Alterations in the dopamine catabolic pathway are known to contribute to the degeneration of nigrostriatal neurons in Parkinson’s disease (PD). The progressive cellular buildup of the highly reactive intermediate 3,4-dihydroxyphenylacetald
Externí odkaz:
https://doaj.org/article/764f555302394f8f85e1259ec0a18767
Autor:
Davide Doni, Federica Cavion, Marco Bortolus, Elisa Baschiera, Silvia Muccioli, Giulia Tombesi, Federica d’Ettorre, Daniele Ottaviani, Elena Marchesan, Luigi Leanza, Elisa Greggio, Elena Ziviani, Antonella Russo, Milena Bellin, Geppo Sartori, Donatella Carbonera, Leonardo Salviati, Paola Costantini
Publikováno v:
Cell Death and Disease, Vol 14, Iss 12, Pp 1-14 (2023)
Abstract Friedreich ataxia (FRDA) is a rare, inherited neurodegenerative disease caused by an expanded GAA repeat in the first intron of the FXN gene, leading to transcriptional silencing and reduced expression of frataxin. Frataxin participates in t
Externí odkaz:
https://doaj.org/article/76a61328d5c945589e294fc868a27afb
Autor:
Lucia Iannotta, Marco Emanuele, Giulia Favetta, Giulia Tombesi, Laurine Vandewynckel, Antonio Jesús Lara Ordóñez, Jean-Michel Saliou, Matthieu Drouyer, William Sibran, Laura Civiero, R. Jeremy Nichols, Panagiotis S. Athanasopoulos, Arjan Kortholt, Marie-Christine Chartier-Harlin, Elisa Greggio, Jean-Marc Taymans
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Mutations in leucine-rich repeat kinase 2 (LRRK2) are a common cause of inherited and sporadic Parkinson’s disease (PD) and previous work suggests that dephosphorylation of LRRK2 at a cluster of heterologous phosphosites is associated to disease. W
Externí odkaz:
https://doaj.org/article/5c7b59f9a8734bce82374910d2ad476b
Autor:
Anna Masato, Nicoletta Plotegher, Francesca Terrin, Michele Sandre, Gaia Faustini, Andrea Thor, Stephen Adams, Giulia Berti, Susanna Cogo, Federica De Lazzari, Camilla Maria Fontana, Paul Anthony Martinez, Randy Strong, Rina Bandopadhyay, Marco Bisaglia, Arianna Bellucci, Elisa Greggio, Luisa Dalla Valle, Daniela Boassa, Luigi Bubacco
Publikováno v:
npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-24 (2023)
Abstract Dopamine dyshomeostasis has been acknowledged among the determinants of nigrostriatal neuron degeneration in Parkinson’s disease (PD). Several studies in experimental models and postmortem PD patients underlined increasing levels of the do
Externí odkaz:
https://doaj.org/article/cf79d21672c5410c9590d5ad6ce4d10a
Autor:
Maria Kedariti, Emanuele Frattini, Pascale Baden, Susanna Cogo, Laura Civiero, Elena Ziviani, Gianluca Zilio, Federico Bertoli, Massimo Aureli, Alice Kaganovich, Mark R. Cookson, Leonidas Stefanis, Matthew Surface, Michela Deleidi, Alessio Di Fonzo, Roy N. Alcalay, Hardy Rideout, Elisa Greggio, Nicoletta Plotegher
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-14 (2022)
Abstract Leucine-rich repeat kinase 2 (LRRK2) is a kinase involved in different cellular functions, including autophagy, endolysosomal pathways, and immune function. Mutations in LRRK2 cause autosomal-dominant forms of Parkinson’s disease (PD). Het
Externí odkaz:
https://doaj.org/article/858ab86634d0401c811792bd3be86640
Autor:
Davide Doni, Federica Cavion, Marco Bortolus, Elisa Baschiera, Silvia Muccioli, Giulia Tombesi, Federica d’Ettorre, Daniele Ottaviani, Elena Marchesan, Luigi Leanza, Elisa Greggio, Elena Ziviani, Antonella Russo, Milena Bellin, Geppo Sartori, Donatella Carbonera, Leonardo Salviati, Paola Costantini
Publikováno v:
Cell Death and Disease, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/f4c0c8a288f342e9aea39235d018dedc
Autor:
Federica De Lazzari, Francesco Agostini, Nicoletta Plotegher, Michele Sandre, Elisa Greggio, Aram Megighian, Luigi Bubacco, Federica Sandrelli, Alexander J. Whitworth, Marco Bisaglia
Publikováno v:
Neurobiology of Disease, Vol 176, Iss , Pp 105941- (2023)
The protein DJ-1 is mutated in rare familial forms of recessive Parkinson's disease and in parkinsonism accompanied by amyotrophic lateral sclerosis symptoms and dementia. DJ-1 is considered a multitasking protein able to confer protection under vari
Externí odkaz:
https://doaj.org/article/3afcbe9bdd464d299fad6c0178bc02f6
Autor:
Susanna Cogo, James E. Tomkins, Nikoleta Vavouraki, Veronica Giusti, Federica Forcellato, Cinzia Franchin, Isabella Tessari, Giorgio Arrigoni, Laura Cendron, Claudia Manzoni, Laura Civiero, Patrick A. Lewis, Elisa Greggio
Publikováno v:
Neurobiology of Disease, Vol 174, Iss , Pp 105858- (2022)
Mutations in SPG11, encoding spatacsin, constitute the major cause of autosomal recessive Hereditary Spastic Paraplegia (HSP) with thinning of the corpus callosum. Previous studies showed that spatacsin orchestrates cellular traffic events through th
Externí odkaz:
https://doaj.org/article/44f7aee8cceb414d95b4e9e6dd924b2f
Autor:
Mirco Peron, Susanna Cogo, Maria Bjelland, Abdulla Bin Afif, Anup Dadlani, Elisa Greggio, Filippo Berto, Jan Torgersen
Publikováno v:
Journal of Magnesium and Alloys, Vol 9, Iss 5, Pp 1806-1819 (2021)
Magnesium alloys have been widely studied as materials for temporary implants, but their use has been limited by their corrosion rate. Recently, coatings have been proven to provide an effective barrier. Though only little explored in the field, Atom
Externí odkaz:
https://doaj.org/article/e31bf964e3d747ca870a5bc18b684c9b