Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Elisa, Avolio"'
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
Cardiovascular disease (CVD) represents the leading cause of mortality and disability all over the world. Identifying new targeted therapeutic approaches has become a priority of biomedical research to improve patient outcomes and quality of life. Th
Externí odkaz:
https://doaj.org/article/88922ba1b8434a27b297a837e77a0596
Autor:
Yue Gu, Elisa Avolio, Valeria V Alvino, Anita C Thomas, Andrew Herman, Poppy J Miller, Niall Sullivan, Ashton Faulkner, Paolo Madeddu
Publikováno v:
Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-16 (2023)
Abstract Background Cardiac steatosis is an early yet overlooked feature of diabetic cardiomyopathy. There is no available therapy to treat this condition. Tyrosine kinase inhibitors (TKIs) are used as first or second-line therapy in different types
Externí odkaz:
https://doaj.org/article/182661119df04ef1b680839919bcac56
Autor:
Monica Cattaneo, Aneta Aleksova, Alberto Malovini, Elisa Avolio, Anita Thomas, Valeria Vincenza Alvino, Michael Kilcooley, Marie Pieronne-Deperrois, Antoine Ouvrard-Pascaud, Anna Maciag, Gaia Spinetti, Sophie Kussauer, Heiko Lemcke, Anna Skorska, Praveen Vasudevan, Stefania Castiglione, Angela Raucci, Robert David, Vincent Richard, Antonio Paolo Beltrami, Paolo Madeddu, Annibale Alessandro Puca
Publikováno v:
Cell Death and Disease, Vol 14, Iss 8, Pp 1-11 (2023)
Abstract Long-living individuals (LLIs) escape age-related cardiovascular complications until the very last stage of life. Previous studies have shown that a Longevity-Associated Variant (LAV) of the BPI Fold Containing Family B Member 4 (BPIFB4) gen
Externí odkaz:
https://doaj.org/article/348033df59064add9787c0ed75ff9450
Autor:
Elisa Avolio, Prashant K. Srivastava, Jiahui Ji, Michele Carrabba, Christopher T. W. Tsang, Yue Gu, Anita C. Thomas, Kapil Gupta, Imre Berger, Costanza Emanueli, Paolo Madeddu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-4 (2023)
Externí odkaz:
https://doaj.org/article/94cdbfa2b1ad4bd79360c8f674462588
Autor:
Federica Riu, Sadie C. Slater, Eva Jover Garcia, Iker Rodriguez-Arabaolaza, Valeria Alvino, Elisa Avolio, Giuseppe Mangialardi, Andrea Cordaro, Simon Satchell, Carlo Zebele, Andrea Caporali, Gianni Angelini, Paolo Madeddu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/fcf57dc341834ec4aa633d47c0e9019b
Autor:
Elisa Avolio, Rajesh Katare, Anita C. Thomas, Andrea Caporali, Daryl Schwenke, Michele Carrabba, Marco Meloni, Massimo Caputo, Paolo Madeddu
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 10 (2022)
Pericytes (PCs) are abundant yet remain the most enigmatic and ill-defined cell population in the heart. Here, we investigated whether PCs can be reprogrammed to aid neovascularization. Primary PCs from human and mouse hearts acquired cytoskeletal pr
Externí odkaz:
https://doaj.org/article/1f8a22258c194244bc80d7e1ca46b0fd
Autor:
Valeria Vincenza Alvino, Anita C. Thomas, Mohamed T. Ghorbel, Filippo Rapetto, Srinivas A. Narayan, Michael Kilcooley, Dominga Iacobazzi, Michele Carrabba, Marco Fagnano, William Cathery, Elisa Avolio, Massimo Caputo, Paolo Madeddu
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
The neonatal heart represents an attractive source of regenerative cells. Here, we report the results of a randomized, controlled, investigator-blinded preclinical study, which assessed the safety and effectiveness of a matrix graft cellularized with
Externí odkaz:
https://doaj.org/article/2389eec8c4f148f888db784ea00ac5a8
Autor:
William Cathery, Ashton Faulkner, Eva Jover, Iker Rodriguez-Arabaolaza, Anita C. Thomas, Elisa Avolio, Massimo Caputo, Paolo Madeddu
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 7 (2021)
Reconstructive surgery of congenital heart disease (CHD) remains inadequate due to the inability of prosthetic grafts to match the somatic growth of pediatric patients. Functionalization of grafts with mesenchymal stem cells (MSCs) may provide a solu
Externí odkaz:
https://doaj.org/article/980fd564c2bf4aceb07a45cfb0803724
Autor:
Michele Carrabba, Eva Jover, Marco Fagnano, Anita C. Thomas, Elisa Avolio, Thomas Richardson, Ben Carter, Giovanni Vozzi, Adam W. Perriman, Paolo Madeddu
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 7 (2020)
Cell therapies are emerging as a new therapeutic frontier for the treatment of ischemic disease. However, femoral occlusions can be challenging environments for effective therapeutic cell delivery. In this study, cell-engineered hybrid scaffolds are
Externí odkaz:
https://doaj.org/article/bc9aff55a077404a86b875b7a92278ec
Autor:
Valeria Vincenza Alvino, Michael Kilcooley, Anita C. Thomas, Michele Carrabba, Marco Fagnano, William Cathery, Elisa Avolio, Dominga Iacobazzi, Mohamed Ghorbel, Massimo Caputo, Paolo Madeddu
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 4 (2020)
Background We have previously reported the possibility of using pericytes from leftovers of palliative surgery of congenital heart disease to engineer clinically certified prosthetic grafts. Methods and Results Here, we assessed the feasibility of us
Externí odkaz:
https://doaj.org/article/061936df9811481ba567e5290313ed83