Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Eliška Švastová"'
Autor:
Miriam Zatovicova, Ivana Kajanova, Monika Barathova, Martina Takacova, Martina Labudova, Lucia Csaderova, Lenka Jelenska, Eliska Svastova, Silvia Pastorekova, Adrian L. Harris, Jaromir Pastorek
Publikováno v:
Cancer & Metabolism, Vol 10, Iss 1, Pp 1-16 (2022)
Abstract Background Hypoxia in the tumor microenvironment (TME) is often the main factor in the cancer progression. Moreover, low levels of oxygen in tumor tissue may signal that the first- or second-line therapy will not be successful. This knowledg
Externí odkaz:
https://doaj.org/article/e6274b37750142d7bf1bd22aaf2132f5
Autor:
Maria Urbanova, Verona Buocikova, Lenka Trnkova, Sabina Strapcova, Viera Horvathova Kajabova, Emma Barreto Melian, Maria Novisedlakova, Miroslav Tomas, Peter Dubovan, Julie Earl, Jozef Bizik, Eliska Svastova, Sona Ciernikova, Bozena Smolkova
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 4, p 2117 (2022)
Due to abundant stroma and extracellular matrix, accompanied by lack of vascularization, pancreatic ductal adenocarcinoma (PDAC) is characterized by severe hypoxia. Epigenetic regulation is likely one of the mechanisms driving hypoxia-induced epithel
Externí odkaz:
https://doaj.org/article/e3b00744b0f14efcb916cefe3c9bfda6
Autor:
Martin Benej, Eliska Svastova, Radivojka Banova, Juraj Kopacek, Adriana Gibadulinova, Martin Kery, Simona Arena, Andrea Scaloni, Monica Vitale, Nicola Zambrano, Ioanna Papandreou, Nicholas C. Denko, Silvia Pastorekova
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Tumor hypoxia represents a severe microenvironmental stress that is frequently associated with acidosis. Cancer cells respond to these stresses with changes in gene expression that promote survival at least in part through pH regulation and metabolic
Externí odkaz:
https://doaj.org/article/9b8010c39ef64e049616ebd117f253ef
Autor:
Sabina Strapcova, Martina Takacova, Lucia Csaderova, Paola Martinelli, Lubomira Lukacikova, Viliam Gal, Juraj Kopacek, Eliska Svastova
Publikováno v:
Cancers, Vol 12, Iss 8, p 2005 (2020)
Hypoxia is a common phenomenon that occurs in most solid tumors. Regardless of tumor origin, the evolution of a hypoxia-adapted phenotype is critical for invasive cancer development. Pancreatic ductal adenocarcinoma is also characterized by hypoxia,
Externí odkaz:
https://doaj.org/article/5029af1ff4cb4257ba8f5e65298e8c1e
Autor:
Adriana Gibadulinova, Petra Bullova, Hynek Strnad, Kamil Pohlodek, Dana Jurkovicova, Martina Takacova, Silvia Pastorekova, Eliska Svastova
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 12, p 4299 (2020)
Solid tumors, including breast cancer, are characterized by the hypoxic microenvironment, extracellular acidosis, and chemoresistance. Hypoxia marker, carbonic anhydrase IX (CAIX), is a pH regulator providing a selective survival advantage to cancer
Externí odkaz:
https://doaj.org/article/7963375b329548c2953043e224afde4a
Autor:
Martina Takacova, Monika Barathova, Miriam Zatovicova, Tereza Golias, Ivana Kajanova, Lenka Jelenska, Olga Sedlakova, Eliska Svastova, Juraj Kopacek, Silvia Pastorekova
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 1, p 246 (2019)
In contrast to human carbonic anhydrase IX (hCA IX) that has been extensively studied with respect to its molecular and functional properties as well as regulation and expression, the mouse ortholog has been investigated primarily in relation to tiss
Externí odkaz:
https://doaj.org/article/419e31ead78c43c2be05eb19e8e76d36
Autor:
Michaela Debreova, Lucia Csaderova, Monika Burikova, Lubomira Lukacikova, Ivana Kajanova, Olga Sedlakova, Martin Kery, Juraj Kopacek, Miriam Zatovicova, Jozef Bizik, Silvia Pastorekova, Eliska Svastova
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 11, p 2745 (2019)
Tumor metastasis is tightly linked with invasive membrane protrusions, invadopodia, formed by actively invading tumor cells. Hypoxia and pH modulation play a role in the invadopodia formation and in their matrix degradation ability. Tumor-associated
Externí odkaz:
https://doaj.org/article/9f5a4d9de6754b9bb5ef577ef5eed845
Autor:
Adriana Annušová, Martina Labudová, Daniel Truchan, Veronika Hegedűšová, Helena Švajdlenková, Matej Mičušík, Mário Kotlár, Lenka Pribusová Slušná, Martin Hulman, Farnoush Salehtash, Anna Kálosi, Lucia Csáderová, Eliška Švastová, Peter Šiffalovič, Matej Jergel, Silvia Pastoreková, Eva Majková
Publikováno v:
ACS Omega, Vol 8, Iss 47, Pp 44497-44513 (2023)
Externí odkaz:
https://doaj.org/article/d1372fcc0f26408aba73dcdeae6d5ad1
Autor:
Martin Balog, Moara Marques de Castro, Jaroslav Čapek, Peter Švec Jr, Martina Takáčová, Lucia Csáderová, Eva Sedláčková, Eliška Švastová, Andrea Školáková, Drahomír Dvorský, Jan Pinc, Vojtěch Hybášek, Jiří Kubásek, Peter Krížik, Jacek Skiba, Oto Bajana, Ahmed Mohamed Hassan Ibrahim
Publikováno v:
Journal of Materials Research and Technology, Vol 25, Iss , Pp 4510-4527 (2023)
The issue of intrinsic microstructural and mechanical instability of Zn-based metals limits their expansion in potential applications of bioresorbable stents and orthopedic fixators. A new concept of stabilization of Zn microstructure by a small frac
Externí odkaz:
https://doaj.org/article/a735e3ada9714b8a97b5c485b360fb19