Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Eliott Le Du"'
Autor:
Eliott Le Du, Jerome Waser
Publikováno v:
Chemical Communications. 59:1589-1604
Although alkynes are one of the smallest functional groups, they are among the most versatile building blocks for organic chemistry, with applications ranging from biochemistry to material sciences. Alkynylation reactions have traditionally relied on
Publikováno v:
Organic Letters. 24:6614-6618
We report a copper-catalyzed alkynylation of azadipeptides using ethynylbenziodoxolone (EBX) reagents. Non-symmetrical ynehydrazides could be obtained in 25-97% yield using azaglycine derivatives as nucleophiles. The transfor-mation is compatible wit
Autor:
Eliott Le Du, Nieves P. Ramirez, Stefano Nicolai, Rosario Scopelliti, Farzaneh Fadaei‐Tirani, Matthew D. Wodrich, Durga Prasad Hari, Jerome Waser
Publikováno v:
Helvetica Chimica Acta. 106
Synthesis of polycyclic aminal heterocycles via decarboxylative cyclisation of dipeptide derivatives
Publikováno v:
Chemical Communications. 58:3473-3476
A convenient synthesis of structurally diverse N-fused aminal heterocycles from easily accessed dipeptides using the hypervalent iodine reagent PIDA in combination with BF3·OEt2 is described.
Autor:
Jerome Waser, Rosario Scopelliti, Eliott Le Du, Elsa Anselmi, Matthew D. Wodrich, Thibaut Duhail, Emmanuel Magnier, Farzaneh Fadaei-Tirani
Publikováno v:
Chemistry (Weinheim an Der Bergstrasse, Germany)
Chemistry-A European Journal
Chemistry-A European Journal, Wiley-VCH Verlag, In press, ⟨10.1002/chem.202101475⟩
Chemistry-A European Journal
Chemistry-A European Journal, Wiley-VCH Verlag, In press, ⟨10.1002/chem.202101475⟩
Ethynylbenziodoxol(on)e (EBX) cyclic hypervalent iodine reagents have become popular reagents for the alkynylation of radicals and nucleophiles, but only offer limited possibilities for further structure and reactivity fine‐tuning. Herein, the synt
Publikováno v:
Chemical communications (Cambridge, England). 58(21)
An oxidative-decarboxylative intramolecular cyclisation of dipeptide derivatives is reported. This transformation is promoted by phenyl iodine(III) diacetate (PIDA) in combination with BF
Autor:
Farzaneh Fadaei-Tirani, Zhaowen Dong, Kay Severin, Rosario Scopelliti, Eliott Le Du, Jerome Waser, Bastian Muriel, Abdusalom A. Suleymanov
Publikováno v:
Organic letters. 22(11)
Donor–acceptor cyclopropanes substituted with 3,3-dialkyltriazenyl groups are described herein. The strong electron-donating character of the triazene renders the cyclopropanes highly reactive, allowing for catalyst-free ring-opening reactions with
Publikováno v:
Chemical Science
A photoredox-catalyzed oxidative decarboxylative coupling of small peptides is reported, giving access to a variety of N,O-acetals. They were used as intermediates for the addition of phenols and indoles, leading to novel peptide scaffolds and biocon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f3adb16c9149eb8bcbdf3d975ec422a
https://infoscience.epfl.ch/record/283954
https://infoscience.epfl.ch/record/283954
Autor:
Yangyang Cheng, Takehiro Kato, Jerome Waser, Bumhee Lim, Naomi Sakai, Abhaya Kumar Mishra, Eliott Le Du, Elija Grinhagena, Dimitri Moreau, Stefan Matile, Anh Tuan Pham
Publikováno v:
Helvetica Chimica Acta, Vol. 104, No e2100085 (2021) pp. 1-9
Helvetica Chimica Acta
Helvetica Chimica Acta
Thiol-mediated uptake is emerging as method of choice to penetrate cells. This study focuses on irreversible covalent inhibitors of thiol-mediated uptake. High-content high-throughput screening of the so far largest collection of hypervalent iodine r