Výsledky vyhledávání - "Eliot P. Botosoa"

Evidence of 13C non-covalent isotope effects obtained by quantitative 13C nuclear magnetic resonance spectroscopy at natural abundance during normal phase liquid chromatography

Autor: Eliot P. Botosoa, Richard J. Robins, Virginie Silvestre, Gérald S. Remaud, Claude Guillou, Jose Manuel Moreno Rojas

Publikováno v: Journal of Chromatography A. 1216:7043-7048

Quantitative isotopic 13C NMR at natural abundance has been used to determine the site-by-site 13C/12C ratios in vanillin and a number of related compounds eluted from silica gel chromatography columns under similar conditions. Head-to-tail isotope f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1a3168b6963502510b71e9cbf6b4984
https://doi.org/10.1016/j.chroma.2009.08.066

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Analytical model for site-specific isotope fractionation in 13C during sorption: Determination by isotopic 13C NMR spectrometry with vanillin as model compound

Autor: Anaïs Lefrançois, Denis Loquet, Richard J. Robins, Gérald S. Remaud, Eliot P. Botosoa, Patrick Höhener, Virginie Silvestre

Publikováno v: Chemosphere
Chemosphere, Elsevier, 2012, 87, pp. 445-452. ⟨10.1016/j.chemosphere.2011.12.023⟩
Chemosphere, 2012, 87, pp.445-452. ⟨10.1016/j.chemosphere.2011.12.023⟩

The aim of this study was to conceive a reactive transport model capable of providing quantitative site-specific enrichment factors for fractionation in 13 C isotopic content during sorption. As test compound the model treats vanillin, for which the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::636a60c6c110bfe66958a6162dcd52a3
https://hal-amu.archives-ouvertes.fr/hal-01505304

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Antibody-Hapten Recognition at the Surface of Functionalized Liposomes Studied by SPR: Steric Hindrance of Pegylated Phospholipids in Stealth Liposomes Prepared for Targeted Radionuclide Delivery

Autor: Mike Maillasson, Marie Mougin-Degraef, Yannick Jacques, Jacques Barbet, Alain Faivre-Chauvet, Jean-François Gestin, Patricia Remaud-Le Saëc, Eliot P. Botosoa

Publikováno v: Journal of Drug Delivery
Journal of Drug Delivery, Hindawi Publishing Corporation, 2011, 2011, pp.368535. ⟨10.1155/2011/368535⟩
Journal of Drug Delivery, Vol 2011 (2011)
Journal of Drug Delivery, 2011, 2011, pp.368535. ⟨10.1155/2011/368535⟩

International audience; Targeted PEGylated liposomes could increase the amount of drugs or radionuclides delivered to tumor cells. They show favorable stability and pharmacokinetics, but steric hindrance of the PEG chains can block the binding of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12dc5bad728f570d6bb1dd7a352126eb
https://www.hal.inserm.fr/inserm-02417966/document

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In vivo 212Pb/212Bi generator using indium-DTPA-tagged liposomes

Autor: A. Le Du, Eliot P. Botosoa, Marie Mougin-Degraef, A. Rauscher, Jacques Barbet, A. Faivre Chauvet, Gilles Montavon

Publikováno v: Radiochimica Acta
Radiochimica Acta, 2011, 99, pp.743-749. ⟨10.1524/ract.2011.1871⟩
Radiochimica Acta, Oldenbourg Wissenschaftsverlag, 2011, 99, pp.743-749. ⟨10.1524/ract.2011.1871⟩

Indium-DTPA-tagged liposomes were studied in the present work as carriers of in vivo 212Pb/ 212Bi generator to be used in targeted alpha therapy. The liposomal uptake of 212Pb, into preformed liposomes, was investigated using different lipophilic che

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b66062772c3c0e7450567af15cb06e2
https://hal.in2p3.fr/in2p3-00617427/file/article-version_finale.pdf

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Quantitative isotopic 13C nuclear magnetic resonance at natural abundance to probe enzyme reaction mechanisms via site-specific isotope fractionation: the case of the chain-shortening reaction for the bioconversion of ferulic acid to vanillin

Autor: Gérald S. Remaud, Donald A. MacKenzie, Christine Blumenstein, Eliot P. Botosoa, Renata A. Kwiecień, Virginie Silvestre, Richard J. Robins

Publikováno v: Analytical biochemistry. 393(2)

Isotope fractionation is a powerful technique by which to probe the reaction mechanism of enzymes. The effect of a heavy isotope on the reaction energetics can be used to predict transition state architecture and reaction mechanism. In order to exami

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe3be1251df0be5fb6d1184470b21da7
https://pubmed.ncbi.nlm.nih.gov/19563771

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Unexpected fractionation in site-specific 13C isotopic distribution detected by quantitative 13C NMR at natural abundance

Autor: Eliot P. Botosoa, Richard J. Robins, Serge Akoka, Elsa Caytan, Virginie Silvestre, Gérald S. Remaud

Publikováno v: Journal of the American Chemical Society. 130(2)

The recent development of 13C NMR to measure absolute 13C/12C ratios at natural abundance has made it possible to examine site-by-site variation at natural abundance. This technique has been applied to two common physical processes: distillation and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::decc837d6f5ca03efbeeb05ca8a58e64
https://pubmed.ncbi.nlm.nih.gov/18092781

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Accurate quantitative 13C NMR spectroscopy: repeatability over time of site-specific 13C isotope ratio determination

Autor: Gérald S. Remaud, Richard J. Robins, Serge Akoka, Elsa Caytan, Eliot P. Botosoa, Virginie Silvestre

Publikováno v: Analytical chemistry. 79(21)

The stability over time (repeatability) for the determination of site-specific 13C/12C ratios at natural abundance by quantitative 13C NMR spectroscopy has been tested on three probes: enriched bilabeled [1,2-13C2]ethanol; ethanol at natural abundanc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d417e8b936e959f7c18be0c40e4b9f65
https://pubmed.ncbi.nlm.nih.gov/17900175

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