Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Elio Madan"'
Publikováno v:
Journal of Applied Toxicology. 13:1-7
Studies were conducted to examine acute hepatic and renal toxicity of dichlorobenzene (DCB) structural isomers. Male Fischer 344 (F344) rats were injected with 2, 3 or 4 mmol kg-1 of 1,2-DCB, 1,3-DCB or 1,4-DCB (o-, m-, p-). Pair-fed control (PFC) an
Publikováno v:
The Journal of Trauma: Injury, Infection, and Critical Care. 30:457-462
Localized bacterial colonization of a 30% total body surface burn (TBSB) wound raises the resting metabolic rate of rats. To determine whether endotoxin (LPS) released in the burn wound contributes to this response, the metabolic rates and colonic te
Publikováno v:
Toxicology. 79(3)
This study examined the contribution of biotransformation by the mixed function oxidase system on hepatic and renal toxicity of 1,2-dichlorobenzene (1,2-DCB). Male Fischer 344 (F344) rats (190-250 g) were pretreated with phenobarbital (PB), beta-naph
Autor:
Dianne K. Anestis, John G. Ball, Elio Madan, Monica A. Valentovic, Gary O. Rankin, Kelly W. Beers, John L. Hubbard
Publikováno v:
Toxicology. 75(2)
Aniline and its halogenated derivatives are widely used as chemical intermediates. The purpose of this study was to determine the hepatotoxic and nephrotoxic potential of the 2-haloanilines. Male Fischer 344 rats (n > or = 4) were injected (i.p.) wit
Publikováno v:
Toxicology. 70(2)
Previous work has demonstrated that cisplatin nephrotoxicity was attenuated in streptozotocin (STZ)-induced diabetic rats. The following studies investigated the hypothesis that renal cisplatin accumulation was reduced in diabetic rats. Male Fischer
Publikováno v:
Toxicology. 60(1-2)
The following studies examined the impact of the diabetic state on cisplatin nephrotoxicity. This study also investigated the potential mechanisms for diabetes mediated reduction of cisplatin toxicity. A diabetic state was induced in male Fischer 344
Publikováno v:
American Journal of Clinical Pathology. 90:450-453
Campylobacter pylori has been implicated in the pathogenesis of peptide ulcer disease. The rapid identification of this organism may depend upon histologic diagnosis, because culture methods are complex and require a minimum of seven days in order to
Publikováno v:
Toxicological Sciences. 12:530-539
Publikováno v:
Fundamental and Applied Toxicology. 12:530-539
The therapeutic use of cisplatin is associated with acute renal failure. The purpose of this study was to determine (a) if streptozotocin (STZ) was toxic to renal proximal tubules and (b) the nephrotoxicity of cisplatin in STZ-diabetic rats. Male Spr
Autor:
Malcolm Slifkin, Elio Madan
Publikováno v:
American journal of clinical pathology. 89(4)
Clostridium difficile is the prime etiologic agent in the production of pseudomembranous colitis by its powerful cytotoxin. The most common test for the toxin is a tissue culture method with neutralization of cytopathic effect by a C. difficile antis