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pro vyhledávání: '"Elio Ciusani"'
Autor:
Marlyse Brawand-Amey, Murielle Brocard, Chin B. Eap, Elio Ciusani, Daniele Zullino, Pierre Baumann
Publikováno v:
Journal of psychopharmacology (Oxford, England). 18(4)
The chiral antidepressant venlafaxine (VEN) is both a serotonin and a norepinephrine uptake inhibitor. CYP2D6 and CYP3A4 contribute to its metabolism, which has been shown to be stereoselective. Ten CYP2D6 genotyped and depressive (F32x and F33x, ICD