Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Elio A. Abbondanzieri"'
Autor:
Elio A. Abbondanzieri, Anne S. Meyer
Publikováno v:
Current Genetics. 65:691-694
The bacterial cytoplasm, once thought to be a relatively undifferentiated reaction medium, has now been recognized to have extensive microstructure. This microstructure includes bacterial microcompartments, inclusion bodies, granules, and even some m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ee85e738eb6c874380a0955744f1c19
https://doi.org/10.1007/s00294-018-00927-x
https://doi.org/10.1007/s00294-018-00927-x
Publikováno v:
Nucleic acids research, 44(17)
Nucleic Acids Research
Nucleic Acids Research
Finding the target site and associating in a specific orientation are essential tasks for DNA-binding proteins. In order to make the target search process as efficient as possible, proteins should not only rapidly diffuse to the target site but also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89413a155c7af7893010b2c5b5801bae
https://doi.org/10.1093/nar/gkw666
https://doi.org/10.1093/nar/gkw666
Autor:
Nynke H. Dekker, Anne S. Meyer, Elio A. Abbondanzieri, David Dulin, M.W. Docter, Natalia N. Vtyurina
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 113(18)
In all organisms, DNA molecules are tightly compacted into a dynamic 3D nucleoprotein complex. In bacteria, this compaction is governed by the family of nucleoid-associated proteins (NAPs). Under conditions of stress and starvation, an NAP called Dps
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::246751069095e1035291969289efb404
https://doi.org/10.1073/pnas.1521241113
https://doi.org/10.1073/pnas.1521241113
Autor:
Cees Dekker, Eugene Kim, Elio A. Abbondanzieri, Mahipal Ganji, Jaco van der Torre, Sung Hyun Kim
Publikováno v:
eLife
eLife, 7
eLife, Vol 7 (2018)
eLife, 7
eLife, Vol 7 (2018)
The three-dimensional organization of DNA is increasingly understood to play a decisive role in vital cellular processes. Many studies focus on the role of DNA-packaging proteins, crowding, and confinement in arranging chromatin, but structural infor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef4ea98bcf4b2b2c6724f0f5821f56e1
Autor:
Anne S. Meyer, Natalia N. Vtyurina, Richard Janissen, Nynke H. Dekker, Dick de Ridder, Zaïda Rivai, Mathia M.A. Arens, Behrouz Eslami-Mossallam, Alexey A. Gritsenko, Liedewij Laan, Irina Artsimovitch, Nicholas D. Sunday, Elio A. Abbondanzieri
Publikováno v:
Cell, 174(5), 1188-1199.e14
Cell 174 (2018) 5
Cell 174 (2018) 5
In stationary-phase Escherichia coli, Dps (DNA-binding protein from starved cells) is the most abundant protein component of the nucleoid. Dps compacts DNA into a dense complex and protects it from damage. Dps has also been proposed to act as a globa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4686d9b716d53b3ad9c3bf248d70c47b
https://doi.org/10.1016/j.cell.2018.06.049
https://doi.org/10.1016/j.cell.2018.06.049
Publikováno v:
Science. 322:1092-1097
The reverse transcriptase (RT) of human immunodeficiency virus (HIV) catalyzes a series of reactions to convert single-stranded viral RNA into double-stranded DNA for host cell integration. This process requires a variety of enzymatic activities, inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1a45af6d4c0ec100a3b0afdba416dd4
https://doi.org/10.1126/science.1163108
https://doi.org/10.1126/science.1163108
Publikováno v:
Nature. 426:684-687
Escherichia coli RNA polymerase (RNAP) synthesizes RNA with remarkable fidelity in vivo. Its low error rate may be achieved by means of a 'proofreading' mechanism comprised of two sequential events. The first event (backtracking) involves a transcrip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eebfb8b6a7047149c72a7f264d816921
https://doi.org/10.1038/nature02191
https://doi.org/10.1038/nature02191
Publikováno v:
Cell. 115:437-447
RNA polymerase (RNAP) transcribes DNA discontinuously, with periods of rapid nucleotide addition punctuated by frequent pauses. We investigated the mechanism of transcription by measuring the effect of both hindering and assisting forces on the trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0ea3464174ff1eb5417ea59f211ea92
https://doi.org/10.1016/s0092-8674(03)00845-6
https://doi.org/10.1016/s0092-8674(03)00845-6
Publikováno v:
Biophysical Journal. 112:214a
While DNA obviously functions as the carrier of genetic information, it may also encode the three-dimensional spatial structure of DNA in cells. Here we study the relationship between structure and sequence in supercoiled DNA, which involves a reorga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc56a8e5d0e2e5bb5356f9991da29f33
https://doi.org/10.1016/j.bpj.2016.11.1182
https://doi.org/10.1016/j.bpj.2016.11.1182