Zobrazeno 1 - 10
of 165
pro vyhledávání: '"Eline T, Luning Prak"'
Autor:
Jianing Fu, Thomas Hsiao, Elizabeth Waffarn, Wenzhao Meng, Katherine D. Long, Kristjana Frangaj, Rebecca Jones, Alaka Gorur, Areen Shtewe, Muyang Li, Constanza Bay Muntnich, Kortney Rogers, Wenyu Jiao, Monica Velasco, Rei Matsumoto, Masaru Kubota, Steven Wells, Nichole Danzl, Shilpa Ravella, Alina Iuga, Elena-Rodica Vasilescu, Adam Griesemer, Joshua Weiner, Donna L. Farber, Eline T. Luning Prak, Mercedes Martinez, Tomoaki Kato, Uri Hershberg, Megan Sykes
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionIt is unknown how intestinal B cell populations and B cell receptor (BCR) repertoires are established and maintained over time in humans. Following intestinal transplantation (ITx), surveillance ileal mucosal biopsies provide a unique opp
Externí odkaz:
https://doaj.org/article/7e3051c91097401d960297af79b254ee
Autor:
Teluguakula Narasaraju, Indira Neeli, Sheila L. Criswell, Amita Krishnappa, Wenzhao Meng, Vasuki Silva, Galyna Bila, Volodymyr Vovk, Zolotukhin Serhiy, Gary L. Bowlin, Nuala Meyer, Eline T. Luning Prak, Marko Radic, Rostyslav Bilyy
Publikováno v:
Biomolecules, Vol 14, Iss 2, p 236 (2024)
Pulmonary fibrosis, severe alveolitis, and the inability to restore alveolar epithelial architecture are primary causes of respiratory failure in fatal COVID-19 cases. However, the factors contributing to abnormal fibrosis in critically ill COVID-19
Externí odkaz:
https://doaj.org/article/c9040d885672481f9ee578e80e3c7ca7
Autor:
Adam J. Fike, Sathi Babu Chodisetti, Nathaniel E. Wright, Kristen N. Bricker, Phillip P. Domeier, Mark Maienschein-Cline, Aaron M. Rosenfeld, Sara A. Luckenbill, Julia L. Weber, Nicholas M. Choi, Eline T. Luning Prak, Malay Mandal, Marcus R. Clark, Ziaur S.M. Rahman
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112512- (2023)
Summary: Germinal centers (GCs), sites of antibody affinity maturation, are organized into dark (DZ) and light (LZ) zones. Here, we show a B cell-intrinsic role for signal transducer and activator of transcription 3 (STAT3) in GC DZ and LZ organizati
Externí odkaz:
https://doaj.org/article/90bb71ba5bd34d068395ef2779c48824
Autor:
Eline T. Luning Prak, Thomas Brooks, Walid Makhoul, Joanne C. Beer, Ling Zhao, Tommaso Girelli, Carsten Skarke, Yvette I. Sheline
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Depression is a common and debilitating disorder in the elderly. Late-life depression (LLD) has been associated with inflammation and elevated levels of proinflammatory cytokines including interleukin (IL)-1β, tumor necrosis factor-alpha, a
Externí odkaz:
https://doaj.org/article/1915818526ab4fcdaeb431e5fe419372
Autor:
Allan Feng, Emily Y. Yang, Andrew Reese Moore, Shaurya Dhingra, Sarah Esther Chang, Xihui Yin, Ruoxi Pi, Elisabeth K.M. Mack, Sara Völkel, Reinhard Geßner, Margrit Gündisch, Andreas Neubauer, Harald Renz, Sotirios Tsiodras, Paraskevi C. Fragkou, Adijat A. Asuni, Joseph E. Levitt, Jennifer G. Wilson, Michelle Leong, Jennifer H. Lumb, Rong Mao, Kassandra Pinedo, Jonasel Roque, Christopher M. Richards, Mikayla Stabile, Gayathri Swaminathan, Maria L. Salagianni, Vasiliki Triantafyllia, Wilhelm Bertrams, Catherine A. Blish, Jan E. Carette, Jennifer Frankovich, Eric Meffre, Kari Christine Nadeau, Upinder Singh, Taia T. Wang, Eline T. Luning Prak, Susanne Herold, Evangelos Andreakos, Bernd Schmeck, Chrysanthi Skevaki, Angela J. Rogers, Paul J. Utz
Publikováno v:
JCI Insight, Vol 8, Iss 3 (2023)
The widespread presence of autoantibodies in acute infection with SARS-CoV-2 is increasingly recognized, but the prevalence of autoantibodies in non–SARS-CoV-2 infections and critical illness has not yet been reported. We profiled IgG autoantibodie
Externí odkaz:
https://doaj.org/article/0af4f2fd58fe44f2af104cc8699674cb
Autor:
Sarah Esther Chang, Allan Feng, Wenzhao Meng, Sokratis A. Apostolidis, Elisabeth Mack, Maja Artandi, Linda Barman, Kate Bennett, Saborni Chakraborty, Iris Chang, Peggie Cheung, Sharon Chinthrajah, Shaurya Dhingra, Evan Do, Amanda Finck, Andrew Gaano, Reinhard Geßner, Heather M. Giannini, Joyce Gonzalez, Sarah Greib, Margrit Gündisch, Alex Ren Hsu, Alex Kuo, Monali Manohar, Rong Mao, Indira Neeli, Andreas Neubauer, Oluwatosin Oniyide, Abigail E. Powell, Rajan Puri, Harald Renz, Jeffrey Schapiro, Payton A. Weidenbacher, Richard Wittman, Neera Ahuja, Ho-Ryun Chung, Prasanna Jagannathan, Judith A. James, Peter S. Kim, Nuala J. Meyer, Kari C. Nadeau, Marko Radic, William H. Robinson, Upinder Singh, Taia T. Wang, E. John Wherry, Chrysanthi Skevaki, Eline T. Luning Prak, Paul J. Utz
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Infection with SARS-CoV2 and the development of Coronavirus disease 2019 (COVID-19) has been linked to induction of autoimmunity and autoantibody production. Here the authors characterise the new-onset IgG autoantibody response in hospitalised patien
Externí odkaz:
https://doaj.org/article/66cae071533b4d708afeb170397e48a7
Autor:
Edd Ricker, Michela Manni, Danny Flores-Castro, Daniel Jenkins, Sanjay Gupta, Juan Rivera-Correa, Wenzhao Meng, Aaron M. Rosenfeld, Tania Pannellini, Mahesh Bachu, Yurii Chinenov, Peter K. Sculco, Rolf Jessberger, Eline T. Luning Prak, Alessandra B. Pernis
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-21 (2021)
Autoimmunity mediated by age-associated B cells (ABC) can affect males and females differently. Here, using a lupus-like mouse model that affects females more severely, the authors observe an ABC mediated and guanine nucleotide exchange factor (GEF)
Externí odkaz:
https://doaj.org/article/908466dd2bb34f6fa842dde7cbf2d877
Autor:
Michelle Miron, Wenzhao Meng, Aaron M. Rosenfeld, Shirit Dvorkin, Maya Meimei Li Poon, Nora Lam, Brahma V. Kumar, Yoram Louzoun, Eline T. Luning Prak, Donna L. Farber
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-14 (2021)
Abstract Background Immune-mediated protection is mediated by T cells expressing pathogen-specific T cell antigen receptors (TCR) that are maintained at diverse sites of infection as tissue-resident memory T cells (TRM) or that disseminate as circula
Externí odkaz:
https://doaj.org/article/c9735e3dd8794a808679dc6e6b7b0c8f
Autor:
Stephanie C Pero, Aaron M Rosenfeld, Girja S Shukla, Linda Mei, Yujing Sun, Wenzhao Meng, David J Fournier, Seth P Harlow, Matthew K Robinson, David N Krag, Eline T Luning Prak, Benjamin C Harman
Publikováno v:
Clinical & Translational Immunology, Vol 11, Iss 8, Pp n/a-n/a (2022)
Abstract Objectives B cell‐mediated immunity can be associated with favorable clinical outcomes in cancer patients. However, the mechanism and features of anti‐tumor immune responses are not well understood. In particular, how B cells expressing
Externí odkaz:
https://doaj.org/article/619dc58a0a8b4fbd8b000d47149c560f
Autor:
Joel R. Wilmore, Brian T. Gaudette, Daniela Gómez Atria, Rebecca L. Rosenthal, Sarah Kim Reiser, Wenzhao Meng, Aaron M. Rosenfeld, Eline T. Luning Prak, David Allman
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Antibody secreting plasma cells are made in response to a variety of pathogenic and commensal microbes. While all plasma cells express a core gene transcription program that allows them to secrete large quantities of immunoglobulin, unique transcript
Externí odkaz:
https://doaj.org/article/0a55c809307e498e94818898c6e453b9