Plasma ApoE elevations are associated with NAFLD: The PREVEND Study.

Autor: Eline H van den Berg, James P Corsetti, Stephan J L Bakker, Robin P F Dullaart

Publikováno v: PLoS ONE, Vol 14, Iss 8, p e0220659 (2019)

Non-alcoholic fatty liver disease (NAFLD) is featured by increased plasma very low density lipoproteins (VLDL). The extent to which plasma apolipoprotein E (ApoE) levels are elevated in NAFLD is unclear. We determined whether plasma ApoE is elevated

Externí odkaz: https://doaj.org/article/7f7725494fe440d7aab890240e9bb479

Branched Chain Amino Acids Are Associated with Physical Performance in Patients with End-Stage Liver Disease

Autor: Maria Camila Trillos-Almanza, Hanna Wessel, Magnolia Martínez-Aguilar, Eline H. van den Berg, Rianne M. Douwes, Han Moshage, Margery A. Connelly, Stephan J. L. Bakker, Vincent E. de Meijer, Robin P. F. Dullaart, Hans Blokzijl

Publikováno v: Biomolecules, Vol 13, Iss 5, p 824 (2023)

Decreased circulating branched chain amino acids (BCAA) represent a prominent change in amino acid profiles in patients with end-stage liver disease (ESLD). These alterations are considered to contribute to sarcopenia and hepatic encephalopathy and m

Externí odkaz: https://doaj.org/article/52adda2308304a418651fd6ac5bacbda

Plasma Calprotectin Levels Associate with Suspected Metabolic-Associated Fatty Liver Disease and All-Cause Mortality in the General Population

Autor: Arno R. Bourgonje, Eline H. van den Berg, Lyanne M. Kieneker, Tom Nilsen, Clara Hidden, Stephan J. L. Bakker, Hans Blokzijl, Robin P. F. Dullaart, Harry van Goor, Amaal E. Abdulle

Publikováno v: International Journal of Molecular Sciences, 23(24):15708. MDPI AG
International Journal of Molecular Sciences; Volume 23; Issue 24; Pages: 15708

Metabolic-associated fatty liver disease (MAFLD) is characterized by hepatic steatosis, metabolic dysregulation, and neutrophilic inflammation. In this study, we hypothesized that systemic levels of plasma calprotectin, as a biomarker of neutrophilic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1c303d46006caff6f3a6438f1f151a3
https://doi.org/10.3390/ijms232415708

High plasma levels of betaine, a trimethylamine N-Oxide-related metabolite, are associated with the severity of cirrhosis

Autor: Eline H, van den Berg, Jose L, Flores-Guerrero, Erwin, Garcia, Margery A, Connelly, Vincent E, de Meijer, Stephan J L, Bakker, Hans, Blokzijl, Robin P F, Dullaart

Publikováno v: Liver International, 43(2), 424-433. Wiley

BACKGROUND AND AIMS: The gut microbiome-related metabolites betaine and trimethylamine N-oxide (TMAO) affect major health issues. In cirrhosis, betaine metabolism may be diminished due to impaired hepatic betaine homocysteine methyltransferase activi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f606ea8c4493ba729e750e2bd5b0ce9
https://pubmed.ncbi.nlm.nih.gov/35585781

Metabolic Associated Fatty Liver Disease: prevalence and determinants

Autor: Eline H. Van den Berg

In this thesis, we examined the epidemiology of MAFLD, its concomitant comorbidities and mediators, environmental and metabolic determinants, genetic factors and outcomes. This thesis describes that MAFLD is highly frequent in the general population,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::342800e6c5ea364a99d10d6ecd7b9d00
https://research.rug.nl/en/publications/37b4f7bb-7682-4923-901c-5b7059e5cf26