Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Eline Dekeyster"'
Autor:
Ramon Roozendaal, Jenny Hendriks, Thierry van Effelterre, Bart Spiessens, Liesbeth Dekking, Laura Solforosi, Dominika Czapska-Casey, Viki Bockstal, Jeroen Stoop, Daniel Splinter, Sarah Janssen, Ben van Baelen, Nadia Verbruggen, Jan Serroyen, Eline Dekeyster, Ariane Volkmann, Yvonne Wollmann, Ricardo Carrion, Luis D. Giavedoni, Cynthia Robinson, Maarten Leyssen, Macaya Douoguih, Kerstin Luhn, Maria Grazia Pau, Jerry Sadoff, An Vandebosch, Hanneke Schuitemaker, Roland Zahn, Benoit Callendret
Publikováno v:
npj Vaccines, Vol 5, Iss 1, Pp 1-11 (2020)
Abstract It has been proven challenging to conduct traditional efficacy trials for Ebola virus (EBOV) vaccines. In the absence of efficacy data, immunobridging is an approach to infer the likelihood of a vaccine protective effect, by translating vacc
Externí odkaz:
https://doaj.org/article/31753f8ec19c4f7ca129201ac99ccb00
Autor:
Eline Dekeyster, Emiel Geeraerts, Tom Buyens, Chris Van den Haute, Veerle Baekelandt, Lies De Groef, Manuel Salinas-Navarro, Lieve Moons
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142067 (2015)
According to the neurotrophin deprivation hypothesis, diminished retrograde delivery of neurotrophic support during an early stage of glaucoma pathogenesis is one of the main triggers that induce retinal ganglion cell (RGC) degeneration. Therefore, i
Externí odkaz:
https://doaj.org/article/7219bc4aa0e04947b0b3ed9a4f0cf6f3
Autor:
Bart Spiessens, Ramon Roozendaal, Liesbeth Dekking, Maria Grazia Pau, Cynthia Robinson, Dominika N. Czapska-Casey, Yvonne Wollmann, Thierry Van Effelterre, Viki Bockstal, Eline Dekeyster, Roland Zahn, Jeroen N Stoop, Kerstin Luhn, Jan Serroyen, Luis D. Giavedoni, Jenny Hendriks, Sarah Janssen, Maarten Leyssen, Ben Van Baelen, Hanneke Schuitemaker, Ricardo Carrion, Daniel Splinter, An Vandebosch, Jerry Sadoff, Ariane Volkmann, Nadia Verbruggen, Macaya Douoguih, Laura Solforosi, Benoit Callendret
Publikováno v:
NPJ VACCINES
npj Vaccines
NPJ Vaccines
npj Vaccines, Vol 5, Iss 1, Pp 1-11 (2020)
npj Vaccines
NPJ Vaccines
npj Vaccines, Vol 5, Iss 1, Pp 1-11 (2020)
It has been proven challenging to conduct traditional efficacy trials for Ebola virus (EBOV) vaccines. In the absence of efficacy data, immunobridging is an approach to infer the likelihood of a vaccine protective effect, by translating vaccine immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a435e1265a441954725ed3930a761f9
http://hdl.handle.net/1887/3562934
http://hdl.handle.net/1887/3562934
Publikováno v:
Neuroscience. 404
Intravenous and/or intrathecal administration of the anti-folate drug methotrexate is a common chemotherapeutic procedure in childhood leukemia. Therapeutic and prophylactic efficacy of these procedures notwithstanding, the occurrence of late adverse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58056c1776b17d00bc91b23ecb28b658
https://pubmed.ncbi.nlm.nih.gov/30703509
https://pubmed.ncbi.nlm.nih.gov/30703509
Autor:
Chris Van den Haute, Emiel Geeraerts, Eline Dekeyster, Lieve Moons, Veerle Baekelandt, Isabelle Scheyltjens, Lies De Groef, Manuel Salinas-Navarro, Marie Claes, Lutgarde Arckens
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 39(12)
Glaucoma is characterized by a progressive loss of retinal ganglion cells (RGCs) in the eye, which ultimately results in visual impairment or even blindness. Because current therapies often fail to halt disease progression, there is an unmet need for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::256c651b543ecba0a0c9d7d58b7af852
https://pubmed.ncbi.nlm.nih.gov/30655352
https://pubmed.ncbi.nlm.nih.gov/30655352
Publikováno v:
Ageing Research Reviews. 24:358-368
Considering the increasing number of elderly in the world's population today, developing effective treatments for age-related pathologies is one of the biggest challenges in modern medical research. Age-related neurodegeneration, in particular, signi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce28efd54f40324d1b33d3555c013884
https://doi.org/10.1016/j.arr.2015.10.004
https://doi.org/10.1016/j.arr.2015.10.004
Autor:
Samme Vreysen, Manuel Salinas-Navarro, Jeroen Aerts, Lieve Moons, Eline Dekeyster, Manuel Vidal-Sanz, Lutgarde Arckens, Francisco J. Valiente-Soriano, Lies De Groef
Publikováno v:
Current Eye Research. 40:1269-1283
Glaucoma is a group of optic neuropathies characterized by the loss of retinal ganglion cells (RGCs). Since ocular hypertension (OHT) is a main risk factor, current therapies are predominantly based on lowering eye pressure. However, a subset of trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53da7fc63b44f4cdf70961354fb7aed6
https://doi.org/10.3109/02713683.2014.990983
https://doi.org/10.3109/02713683.2014.990983
Autor:
Lieve Moons, Inge Van Hove, Mieke Verslegers, Eline Dekeyster, Lutgarde Arckens, Tjing-Tjing Hu, Ilse Gantois, Rudi D'Hooge
Publikováno v:
Brain Structure and Function. 220:1601-1617
Matrix metalloproteinase-2 (MMP-2) is a highly studied proteolytic enzyme, involved in many detrimental and beneficial functions throughout the body, and also active in the central nervous system (CNS). MMP-2 is profoundly expressed in the developing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7222406e9fce8428289680abc73f3f23
https://doi.org/10.1007/s00429-014-0747-3
https://doi.org/10.1007/s00429-014-0747-3
Publikováno v:
Molecular and Cellular Neuroscience. 57:63-72
During the first postnatal days in the mouse, granule cells (GCs) undergo massive proliferation, which then gradually decreases. Matrix metalloproteinase-2 (MMP-2), a Zn(2+)-dependent proteolytic enzyme, is involved in a wide variety of pathological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cc08018f0f48b60b3883b2e0b421e65
https://doi.org/10.1016/j.mcn.2013.10.001
https://doi.org/10.1016/j.mcn.2013.10.001
Autor:
Evy Lefevere, Lies De Groef, Lieve Moons, Eline Dekeyster, Ingeborg Stalmans, Manuel Salinas-Navarro, Emiel Geeraerts
Mouse disease models have proven indispensable in glaucoma research, yet the complexity of the vast number of models and mouse strains has also led to confusing findings. In this study, we evaluated baseline intraocular pressure, retinal histology, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae8ddb7bb7bfcb2300ac520896334289
https://lirias.kuleuven.be/handle/123456789/522432
https://lirias.kuleuven.be/handle/123456789/522432