Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Eline A. J. Willemse"'
Autor:
Katharina Bolsewig, Hester Blok, Eline A. J. Willemse, Rob B. M. Groot Zwaaftink, Minke Kooistra, Ellen M. A. Smets, Charlotte E. Teunissen, Leonie N. C. Visser
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 16, Iss 1, Pp n/a-n/a (2024)
Abstract INTRODUCTION We aimed to evaluate informal caregivers’ attitudes toward undergoing and future implementation of blood‐based biomarkers (BBBM) testing for Alzheimer's disease (AD). METHODS We explored caregivers’ perspectives, by combin
Externí odkaz:
https://doaj.org/article/cc70125f107b401a810c29b05b85b323
Autor:
Katharina Waury, Eline A. J. Willemse, Eugeen Vanmechelen, Henrik Zetterberg, Charlotte E. Teunissen, Sanne Abeln
Publikováno v:
Biomarker Research, Vol 10, Iss 1, Pp 1-21 (2022)
Abstract Fluid protein biomarkers are important tools in clinical research and health care to support diagnosis and to monitor patients. Especially within the field of dementia, novel biomarkers could address the current challenges of providing an ea
Externí odkaz:
https://doaj.org/article/602f444ab3904b1fa9427a2369a5a662
Autor:
Lisa Vermunt, Marco Otte, Inge M. W. Verberk, Joep Killestein, Afina W. Lemstra, Wiesje M. van derFlier, Yolande A. L. Pijnenburg, Everard G. B. Vijverberg, Femke H. Bouwman, Gido Gravesteijn, Wilma D. J. van deBerg, Philip Scheltens, Argonde C. vanHarten, Eline A. J. Willemse, Charlotte E. Teunissen
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 9, Iss 11, Pp 1832-1837 (2022)
Abstract Interpretation of axonal damage biomarker Neurofilament Light chain (NfL) concentrations is difficult due to the lack of age‐specific and disease‐specific reference values. We here developed an interactive interface to support interpreta
Externí odkaz:
https://doaj.org/article/bb2c5e3e1a0f400bab820db7e4aec1eb
Autor:
Nicole Rübsamen, Eline A. J. Willemse, David Leppert, Heinz Wiendl, Matthias Nauck, André Karch, Jens Kuhle, Klaus Berger
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
IntroductionNeurofilament light (NfL) can be detected in blood of healthy individuals and at elevated levels in those with different neurological diseases. We investigated if the choice of biological matrix can affect results when using NfL as biomar
Externí odkaz:
https://doaj.org/article/d8bbfef6c53546cf9d5d32514aab8833
Autor:
Flora H. Duits, Kirsten E. J. Wesenhagen, Laura Ekblad, Emma Wolters, Eline A. J. Willemse, ADNI, Philip Scheltens, Wiesje M. van der Flier, Charlotte E. Teunissen, Pieter Jelle Visser, Betty M. Tijms
Publikováno v:
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-25 (2021)
Abstract Background As Alzheimer’s disease (AD) pathology presents decades before dementia manifests, unbiased biomarker cut-points may more closely reflect presence of pathology than clinically defined cut-points. Currently, unbiased cerebrospinal
Externí odkaz:
https://doaj.org/article/efd993577f5d47908e8a57e1a7f456c8
Autor:
Wouter J. C. vanBallegoij, Stephanie I.W. van deStadt, Irene C. Huffnagel, Stephan Kemp, Eline A. J. Willemse, Charlotte E. Teunissen, Marc Engelen
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 7, Iss 11, Pp 2127-2136 (2020)
Abstract Objective To explore the potential of neurofilament light (NfL) and glial fibrillary acidic protein (GFAP) as biomarkers of spinal cord degeneration in adrenoleukodystrophy, as objective treatment‐outcome parameters are needed. Methods Pla
Externí odkaz:
https://doaj.org/article/161dd86984fa48c7bece7abb894f59b8
Autor:
Ilham Y. Abdi, Nour K. Majbour, Eline A. J. Willemse, Wilma D. J. van de Berg, Brit Mollenhauer, Charlotte E. Teunissen, Omar M. El-Agnaf
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Background: The role of cerebrospinal fluid (CSF) alpha-synuclein as a potential biomarker has been challenged mainly due to variable preanalytical measures between laboratories. To evaluate the impact of the preanalytical factors contributing to suc
Externí odkaz:
https://doaj.org/article/3cc31443f7a74e0e8788d872e5a3f6b3
Autor:
Eline A. J. Willemse, Betty M. Tijms, Bart N. M. vanBerckel, Nathalie Le Bastard, Wiesje M. van derFlier, Philip Scheltens, Charlotte E. Teunissen
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 13, Iss 1, Pp n/a-n/a (2021)
Abstract Introduction We evaluated for two novel automated biomarker assays how cerebrospinal fluid (CSF) amyloid beta (Aβ)1– 42‐ratios improved the concordance with amyloid positron emission tomography (PET) positivity compared to Aβ1– 42 al
Externí odkaz:
https://doaj.org/article/2a6e8880b9de4e72b8c57fe0375b41c7
Autor:
Katharina Bolsewig, Yanaika S. Hok-A-Hin, Federica N. Sepe, Lynn Boonkamp, Dirk Jacobs, Giovanni Bellomo, Federico Paolini Paoletti, Eugeen Vanmechelen, Charlotte E. Teunissen, Lucilla Parnetti, Eline A. J. Willemse
Publikováno v:
Journal of Alzheimer's disease : JAD, 90(1), 363-380. IOS Press
Bolsewig, K, Hok-A-Hin, Y S, Sepe, F N, Boonkamp, L, Jacobs, D, Bellomo, G, Paoletti, F P, Vanmechelen, E, Teunissen, C E, Parnetti, L & Willemse, E A J 2022, ' A Combination of Neurofilament Light, Glial Fibrillary Acidic Protein, and Neuronal Pentraxin-2 Discriminates Between Frontotemporal Dementia and Other Dementias ', Journal of Alzheimer's disease : JAD, vol. 90, no. 1, pp. 363-380 . https://doi.org/10.3233/JAD-220318
Bolsewig, K, Hok-A-Hin, Y S, Sepe, F N, Boonkamp, L, Jacobs, D, Bellomo, G, Paoletti, F P, Vanmechelen, E, Teunissen, C E, Parnetti, L & Willemse, E A J 2022, ' A Combination of Neurofilament Light, Glial Fibrillary Acidic Protein, and Neuronal Pentraxin-2 Discriminates Between Frontotemporal Dementia and Other Dementias ', Journal of Alzheimer's disease : JAD, vol. 90, no. 1, pp. 363-380 . https://doi.org/10.3233/JAD-220318
Background: The differential diagnosis of frontotemporal dementia (FTD) is still a challenging task due to its symptomatic overlap with other neurological diseases and the lack of biofluid-based biomarkers. Objective: To investigate the diagnostic po
Autor:
Marie-Paule E van Engelen, Hans Heijst, Eline A J Willemse, Mardien L Oudega, Lisa Vermunt, Philip Scheltens, Everard G B Vijverberg, Yolande A L Pijnenburg, Charlotte E Teunissen
Publikováno v:
van Engelen, M-P E, Heijst, H, Willemse, E A J, Oudega, M L, Vermunt, L, Scheltens, P, Vijverberg, E G B, Pijnenburg, Y A L & Teunissen, C E 2023, ' Urine as matrix for analysis of neurofilament light chain is not suitable to distinguish frontotemporal dementia from psychiatric diseases ', Brain Communications, vol. 5, no. 2, fcad120 . https://doi.org/10.1093/braincomms/fcad120
Brain Communications, 5(2):fcad120. Oxford University Press
Brain Communications, 5(2):fcad120. Oxford University Press
The clinical overlap of frontotemporal dementia and primary psychiatric diseases hampers diagnostic distinction, leading to frequent misdiagnosis and diagnostic delay. Neurofilament light chain has shown great potential in CSF and blood for the disti