Zobrazeno 1 - 10 of 24 pro vyhledávání: '"Elina Zorde-Khvalevsky"'
1
Akademický článek
Fibroblast growth factors induce hepatic tumorigenesis post radiofrequency ablation
Autor: Aurelia Markezana, Mor Paldor, Haixing Liao, Muneeb Ahmed, Elina Zorde-Khvalevsky, Nir Rozenblum, Matthias Stechele, Lukas Salvermoser, Flinn Laville, Salome Goldmann, Nofar Rosenberg, Tomas Andrasina, Jens Ricke, Eithan Galun, Shraga Nahum Goldberg
Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Image-guided radiofrequency ablation (RFA) is used to treat focal tumors in the liver and other organs. Despite potential advantages over surgery, hepatic RFA can promote local and distant tumor growth by activating pro-tumorigenic growth fa
Externí odkaz: https://doaj.org/article/03595b935ef7476ea759175acb308d21
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2
Akademický článek
DSP107 combines inhibition of CD47/SIRPα axis with activation of 4-1BB to trigger anticancer immunity
Autor: Ewa Cendrowicz, Lisa Jacob, Shirley Greenwald, Ami Tamir, Iris Pecker, Rinat Tabakman, Lucy Ghantous, Liat Tamir, Roy Kahn, Jasmine Avichzer, Alexandra Aronin, Shira Amsili, Elina Zorde-Khvalevsky, Yosi Gozlan, Martijn Vlaming, Gerwin Huls, Tom van Meerten, Michal Elhalel Dranitzki, Adam Foley-Comer, Yaron Pereg, Amnon Peled, Ayelet Chajut, Edwin Bremer
Publikováno v: Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-16 (2022)
Abstract Background Treatment of Diffuse Large B Cell Lymphoma (DLBCL) patients with rituximab and the CHOP treatment regimen is associated with frequent intrinsic and acquired resistance. However, treatment with a CD47 monoclonal antibody in combina
Externí odkaz: https://doaj.org/article/88f427a2882642b7b2f32986f378f0e2
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3
Akademický článek
Incomplete thermal ablation of tumors promotes increased tumorigenesis
Autor: Aurelia Markezana, S. Nahum Goldberg, Gaurav Kumar, Elina Zorde-Khvalevsky, Svetlana Gourevtich, Nir Rozenblum, Eithan Galun, Muneeb Ahmed
Publikováno v: International Journal of Hyperthermia, Vol 38, Iss 1, Pp 263-272 (2021)
Purpose While systemic tumor-stimulating effects can occur following ablation of normal liver linked to the IL-6/HGF/VEGF cytokinetic pathway, the potential for tumor cells themselves to produce these unwanted effects is currently unknown. Here, we s
Externí odkaz: https://doaj.org/article/2496828e71df4daaafb9f46fdc38b738
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4
Akademický článek
Moderate hyperthermic heating encountered during thermal ablation increases tumor cell activity
Autor: Aurelia Markezana, Muneeb Ahmed, Gaurav Kumar, Elina Zorde-Khvalevsky, Nir Rozenblum, Eithan Galun, S. Nahum Goldberg
Publikováno v: International Journal of Hyperthermia, Vol 37, Iss 1, Pp 119-129 (2020)
Purpose The aim of this study was to determine whether moderate hyperthermic doses, routinely encountered in the periablational zone during thermal ablation, activate tumor cells sufficiently to secrete pro-tumorigenic factors that can induce increas
Externí odkaz: https://doaj.org/article/42fda19c01854a878a3eed40c7e2f4cc
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6
Incomplete thermal ablation of tumors promotes increased tumorigenesis
Autor: Nir Rozenblum, Muneeb Ahmed, S. Nahum Goldberg, Eithan Galun, Svetlana Gourevtich, Elina Zorde-Khvalevsky, Aurelia Markezana, Gaurav Kumar
Publikováno v: International Journal of Hyperthermia, Vol 38, Iss 1, Pp 263-272 (2021)
Purpose While systemic tumor-stimulating effects can occur following ablation of normal liver linked to the IL-6/HGF/VEGF cytokinetic pathway, the potential for tumor cells themselves to produce these unwanted effects is currently unknown. Here, we s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4009329f06388ebbb3c631017ecfa31e
https://doi.org/10.1080/02656736.2021.1887942
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7
Moderate hyperthermic heating encountered during thermal ablation increases tumor cell activity
Autor: Nir Rozenblum, Muneeb Ahmed, Gaurav Kumar, Elina Zorde-Khvalevsky, Aurelia Markezana, Eithan Galun, S. Nahum Goldberg
Publikováno v: Int J Hyperthermia
International Journal of Hyperthermia, Vol 37, Iss 1, Pp 119-129 (2020)
Purpose The aim of this study was to determine whether moderate hyperthermic doses, routinely encountered in the periablational zone during thermal ablation, activate tumor cells sufficiently to secrete pro-tumorigenic factors that can induce increas
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd2558dad4a9f9fd551ca51143433bd9
https://doi.org/10.1080/02656736.2020.1714084
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8
790 DSP502 — A novel approach for targeting TIGIT and PD1 pathways for cancer immunotherapy
Autor: Matthew P. Weber, Elina Zorde-Khvalevsky, Amnon Peled, Adam Foley-Comer, Ami Tamir, Ayelet Chajut, Lucy Ganthous, Alexandra Aronin, Rinat Tabakman, Shirley Greenwald, Jasmine Avichzer, Roy Kahn, Mark L. Tykocinski, Iris Pecker, Liat Ben Gigi Tamir, Michal Michal Elhalel Dranitzki
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundTIGIT, an inhibitory immune checkpoint, is a target of interest for immuno-oncology combination therapies. TIGIT is part of a complex molecular network containing four receptors (DNAM1, TIGIT, PVRIG and CD96) and two ligands (PVR and PVRL2)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ace81f6d30f90242de6e37a20b6a0608
https://doaj.org/article/9d1d813fb3514e5b91af359675727c2a
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9
Short treatment of peripheral blood cells product with Fas ligand using closed automated cell processing system significantly reduces immune cell reactivity of the graft in vitro and in vivo
Autor: Galina Rodionov, Michal Rosenzwaig, Michal Schrift Tzadok, Moran Kvint, Elazar Gevir, Elina Zorde-Khvalevsky, Amnon Peled, Shai Yarkoni, Amos Ofer
Publikováno v: Bone marrow transplantation. 57(8)
Mobilized peripheral blood cells (MPBCs) graft and peripheral blood cells apheresis are used for bone marrow transplantation and for treatment of graft versus host disease (GvHD). We demonstrate that a short treatment of MPBCs with Fas ligand (FasL,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53e1115ac1eccc8dd8ff0645a15dc160
https://pubmed.ncbi.nlm.nih.gov/35538142
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10
The lncRNA H19-Derived MicroRNA-675 Promotes Liver Necroptosis by Targeting FADD
Autor: Daniel Goldenberg, Jessica Zucman-Rossi, Mélissa Léveillé, Alina Simerzin, Mila Rivkin, Maytal Gefen, Hilla Giladi, Eithan Galun, Zohar Bromberg, Rona Harari-Steinfeld, Stefano Caruso, Mordechay Gerlic, Ezra Ella, Tomer Friehmann, Elina Zorde-Khvalevsky, Jennifer L. Estall
Publikováno v: Cancers, Vol 13, Iss 411, p 411 (2021)
Cancers
Cancers, MDPI, 2021, 13 (3), pp.411. ⟨10.3390/cancers13030411⟩
Cancers, 2021, 13 (3), pp.411. ⟨10.3390/cancers13030411⟩
Volume 13
Issue 3
Simple Summary Liver cancer develops mostly in a chronically inflamed liver. The inflammation process can enhance or suppress the development of liver cancer. H19 is a noncoding RNA that is upregulated in inflamed livers. The role of H19 in liver can
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d5cab01a6c202c1f507b8a7c27c8e61
https://www.mdpi.com/2072-6694/13/3/411
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