Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Elina Kuokkanen"'
Autor:
Marika Runsala, Elina Kuokkanen, Eveliina Uski, Vid Šuštar, Meryem Özge Balci, Johanna Rajala, Vilma Paavola, Pieta K. Mattila
Publikováno v:
Cells, Vol 12, Iss 21, p 2566 (2023)
In B cells, antigen processing and peptide-antigen (pAg) presentation is essential to ignite high-affinity antibody responses with the help of cognate T cells. B cells efficiently internalize and direct specific antigens for processing and loading on
Externí odkaz:
https://doaj.org/article/2d5d8a69c76c44dab7582fde1a410b66
Autor:
Alexey V. Sarapulov, Petar Petrov, Sara Hernández-Pérez, Vid Šuštar, Elina Kuokkanen, Lena Cords, Rufus V. M. Samuel, Marika Vainio, Marco Fritzsche, Yolanda R. Carrasco, Pieta K. Mattila
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Efficient generation of antibodies by B cells is one of the prerequisites of protective immunity. B cell activation by cognate antigens via B cell receptors (BCRs), or pathogen-associated molecules through pattern-recognition receptors, such as Toll-
Externí odkaz:
https://doaj.org/article/3400b152011249b4b78cfb6d5632f6cc
Autor:
Pieta K. Mattila, Alexey V. Sarapulov, Luqman O Awoniyi, Marika Vainio, J Rajala, V Paavola, Elina Kuokkanen, Eija Jokitalo, S Fórsten, Vid Šuštar, Andreas Bruckbauer, Helena Vihinen, Petar Petrov, Sara Hernández-Pérez
Publikováno v:
Journal of Cell Science. 133
In order to mount high-affinity antibody responses, B cells internalise specific antigens and process them into peptides loaded onto MHCII for presentation to T helper cells (TH cells). While the biochemical principles of antigen processing and MHCII
Autor:
Vid Šuštar, Petar Petrov, Yolanda R. Carrasco, Marco Fritzsche, Rufus V. M. Samuel, Elina Kuokkanen, Marika Vainio, Lena Cords, Alexey V. Sarapulov, Sara Hernández-Pérez, Pieta K. Mattila
Publikováno v:
Frontiers in Immunology
Digital.CSIC. Repositorio Institucional del CSIC
instname
Frontiers in Immunology, Vol 11 (2020)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Frontiers in Immunology, Vol 11 (2020)
Efficient generation of antibodies by B cells is one of the prerequisites of protective immunity. B cell activation by cognate antigens via B cell receptors (BCRs), or pathogen-associated molecules through pattern-recognition receptors, such as Toll-
Autor:
Alexey V Sarapulov, Petar Petrov, Sara Hernández-Pérez, Vid Šuštar, Elina Kuokkanen, Rufus Vinod, Marika Vainio, Lena Cords, Marco Fritzsche, Yolanda R Carrasco, Pieta K Mattila
Efficient generation of antibodies by B cells is one of the prerequisites of protective immunity. B cells, activated by cognate antigens via B cell receptors (BCR) or pathogen-associated molecules through pattern-recognition receptors, such as TLRs,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff97f995e14e6c3f86b21def63dbe85d
Publikováno v:
Traffic. 16:311-326
B cells form an essential part of the adaptive immune system by producing specific antibodies that can neutralize toxins and target infected or malignant cells for destruction. During B cell activation, a fundamental role is played by a specialized i
Autor:
Pirkko Heikinheimo, Elina Kuokkanen, Øivind Nilssen, Helle Bagterp Klenow, Elisabeth Kjeldsen Buvang, Hilde Monica Frostad Riise Stensland, Dag Malm, Gabrio Frantzen
Publikováno v:
Human Mutation. 36(6):581-586
α-Mannosidosis is an autosomal recessive lysosomal storage disorder caused by mutations in the MAN2B1 gene, encoding lysosomal α-mannosidase. The disorder is characterized by a range of clinical phenotypes of which the major manifestations are ment
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 82:300-311
The main function of lysosomal proteins is to degrade cellular macromolecules. We purified a novel lysosomal protein to homogeneity from bovine kidneys. By gene annotation, this protein is defined as a bovine phospholipase B-like protein 1 (bPLBD1) a
Publikováno v:
ChemMedChem. 7:1943-1953
Acid α-glucosidase (GAA) is a lysosomal enzyme and a pharmacological target for Pompe disease, an inherited lysosomal storage disorder (LSD). An emerging treatment for LSDs is the use of pharmacological chaperones, small molecules that enhance total