Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Elina I. Zuniga"'
Autor:
James A. Harker, Trever T. Greene, Burton E. Barnett, Phuc Bao, Aleksandr Dolgoter, Elina I. Zuniga
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The IL-6 cytokine family signals through the common signal transduction molecule gp130 combined with a cytokine-specific receptor. Gp130 signaling on CD4 T cells is vital in controlling chronic infection of mice with lymphocytic choriomeningitis viru
Externí odkaz:
https://doaj.org/article/50f2afff8074497a9c4c07c1865892ed
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Survival from influenza A virus (IAV) infection largely depends on an intricate balance between pathogen clearance and immunomodulation in the lung. We demonstrate that genetic alteration of the glycan heparan sulfate (HS) in CD11c + cells v
Externí odkaz:
https://doaj.org/article/09c5b7c89e264bfeaa9477debe1c08cb
Autor:
Lauren K. Quezada, Wenhao Jin, Yi Chia Liu, Eleanor S. Kim, Zhaoren He, Cynthia S. Indralingam, Tiffani Tysl, Lara Labarta-Bajo, Ellen J. Wehrens, Yeara Jo, Katelynn R. Kazane, Christopher Hattori, Elina I. Zuniga, Gene W. Yeo, John T. Chang
Publikováno v:
PLoS Biology, Vol 21, Iss 1 (2023)
During a microbial infection, responding CD8+ T cells give rise to effector cells that provide acute host defense and memory cells that provide sustained protection. An alternative outcome is exhaustion, a state of T cell dysfunction that occurs in t
Externí odkaz:
https://doaj.org/article/bbb5610089ad4f7d9b1da7b31f9b0300
Autor:
Melisa Gorosito Serrán, Facundo Fiocca Vernengo, Laura Almada, Cristian G. Beccaria, Yamila Gazzoni, Pablo F. Canete, Jonathan A. Roco, Jimena Tosello Boari, Maria Cecilia Ramello, Ellen Wehrens, Yeping Cai, Elina I. Zuniga, Carolina L. Montes, Ian A. Cockburn, Eva V. Acosta Rodriguez, Carola G. Vinuesa, Adriana Gruppi
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
During infections with protozoan parasites or some viruses, T cell immunosuppression is generated simultaneously with a high B cell activation. It has been described that, as well as producing antibodies, plasmablasts, the differentiation product of
Externí odkaz:
https://doaj.org/article/e2cf7f337a5340039ee73c984b6bf218
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 2, Pp 86-97 (2020)
While recent research points to the importance of glycans in cancer immunity, knowledge on functional mechanisms is lacking. In lung carcinoma among other tumors, anti-tumor immunity is suppressed; and while some recent therapies boost T-cell mediate
Externí odkaz:
https://doaj.org/article/72aa0b090708413fb068436f35021a19
Autor:
Alexandra Tsitsiklis, Derek J. Bangs, Lydia K. Lutes, Shiao W. Chan, Kristina M. Geiger, Andrew J. Modzelewski, Lara Labarta-Bajo, Yang Wang, Elina I. Zuniga, Shaodong Dai, Ellen A. Robey
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The CD8+ T cell response to the intracellular parasite Toxoplasma gondii varies dramatically between mouse strains, resulting in stark differences in control of the parasite. Protection in BALB/c mice can be attributed to an unusually strong and prot
Externí odkaz:
https://doaj.org/article/4aa56ee319d5430d9240f09b8b10ac7c
Autor:
Trever T. Greene, Elina I. Zuniga
Publikováno v:
Viruses, Vol 13, Iss 9, p 1839 (2021)
Type I Interferons (IFN-I) are a family of potent antiviral cytokines that act through the direct restriction of viral replication and by enhancing antiviral immunity. However, these powerful cytokines are a caged lion, as excessive and sustained IFN
Externí odkaz:
https://doaj.org/article/776da3ba45bb471798728668d86e081d
Autor:
Roland El Ghazal, Xin Yin, Scott C. Johns, Lee Swanson, Monica Macal, Pradipta Ghosh, Elina I. Zuniga, Mark M. Fuster
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 18, Iss 5, Pp 294-306 (2016)
In cancer, proteoglycans have been found to play roles in facilitating the actions of growth factors, and effecting matrix invasion and remodeling. However, little is known regarding the genetic and functional importance of glycan chains displayed by
Externí odkaz:
https://doaj.org/article/1c9a0b4e11d24672b536bd3b90602dca
Publikováno v:
Immunological reviews. 309(1)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), has caused millions of deaths in the past two years. Although initially little was understood about this virus, recent research
Publikováno v:
Trends Immunol
Trends in immunology, vol 43, iss 7
Trends in immunology, vol 43, iss 7
Emerging immunotherapies offer a new hope for cancer patients but are not always effective even when a tumor is recognized by the immune system. Baldominos and colleagues address this challenge by characterizing a resilient niche of metabolically uni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::702d24cf9ff9e0c7a3de4699f0d84241
https://europepmc.org/articles/PMC9674368/
https://europepmc.org/articles/PMC9674368/