Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Elina Hämäläinen"'
Autor:
Natallie Kajevu, Anssi Lipponen, Pedro Andrade, Ivette Bañuelos, Noora Puhakka, Elina Hämäläinen, Teemu Natunen, Mikko Hiltunen, Asla Pitkänen
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 14049 (2023)
We tested a hypothesis that in silico-discovered compounds targeting traumatic brain injury (TBI)-induced transcriptomics dysregulations will mitigate TBI-induced molecular pathology and augment the effect of co-administered antiseizure treatment, th
Externí odkaz:
https://doaj.org/article/1f3bc2149fe249bdb536c8bf79bb03a8
Autor:
Riccardo De Feo, Elina Hämäläinen, Eppu Manninen, Riikka Immonen, Juan Miguel Valverde, Xavier Ekolle Ndode-Ekane, Olli Gröhn, Asla Pitkänen, Jussi Tohka
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
Registration-based methods are commonly used in the automatic segmentation of magnetic resonance (MR) brain images. However, these methods are not robust to the presence of gross pathologies that can alter the brain anatomy and affect the alignment o
Externí odkaz:
https://doaj.org/article/c850e16bb8b54a38ab7a0292a30b4aec
Autor:
Eppu Manninen, Karthik Chary, Riccardo De Feo, Elina Hämäläinen, Pedro Andrade, Tomi Paananen, Alejandra Sierra, Jussi Tohka, Olli Gröhn, Asla Pitkänen
Publikováno v:
Biomedicines, Vol 10, Iss 11, p 2721 (2022)
It is necessary to develop reliable biomarkers for epileptogenesis and cognitive impairment after traumatic brain injury when searching for novel antiepileptogenic and cognition-enhancing treatments. We hypothesized that a multiparametric magnetic re
Externí odkaz:
https://doaj.org/article/c63f6e75523345e79282156b0003c5e6
Autor:
Xavier Ekolle Ndode-Ekane, Riikka Immonen, Elina Hämäläinen, Eppu Manninen, Pedro Andrade, Robert Ciszek, Tomi Paananen, Olli Gröhn, Asla Pitkänen
Publikováno v:
Biomedicines, Vol 10, Iss 9, p 2295 (2022)
Brain atrophy induced by traumatic brain injury (TBI) progresses in parallel with epileptogenesis over time, and thus accurate placement of intracerebral electrodes to monitor seizure initiation and spread at the chronic postinjury phase is challengi
Externí odkaz:
https://doaj.org/article/91d84f0b118949bdb0f83b57d7cff234
Autor:
Jenni Kyyriäinen, Natallie Kajevu, Ivette Bañuelos, Leonardo Lara, Anssi Lipponen, Silvia Balosso, Elina Hämäläinen, Shalini Das Gupta, Noora Puhakka, Teemu Natunen, Teresa Ravizza, Annamaria Vezzani, Mikko Hiltunen, Asla Pitkänen
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 19, p 10555 (2021)
We assessed the effect of antioxidant therapy using the Food and Drug Administration-approved respiratory drug N-acetylcysteine (NAC) or sulforaphane (SFN) as monotherapies or duotherapy in vitro in neuron-BV2 microglial co-cultures and validated the
Externí odkaz:
https://doaj.org/article/b998370c5ed947969d9f9c88922b1f47
Autor:
Anssi Lipponen, Teemu Natunen, Mika Hujo, Robert Ciszek, Elina Hämäläinen, Jussi Tohka, Mikko Hiltunen, Jussi Paananen, David Poulsen, Emilia Kansanen, Xavier Ekolle Ndode-Ekane, Anna-Liisa Levonen, Asla Pitkänen
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 21, p 5395 (2019)
We developed a pipeline for the discovery of transcriptomics-derived disease-modifying therapies and used it to validate treatments in vitro and in vivo that could be repurposed for TBI treatment. Desmethylclomipramine, ionomycin, sirolimus and trimi
Externí odkaz:
https://doaj.org/article/f6399f138e4643869ce0fdf7641b06bc
This study sought to understand pre-service teachers’ abilities to evaluate and justify the credibility of online texts on a common myth in education—learning styles. The participants were 169 pre-service teachers who completed a credibility eval
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ec49660039b39f6ddd3f6611944459e
https://doi.org/10.31219/osf.io/3zwk8
https://doi.org/10.31219/osf.io/3zwk8
Autor:
Pitkänen, Eppu Manninen, Karthik Chary, Riccardo De Feo, Elina Hämäläinen, Pedro Andrade, Tomi Paananen, Alejandra Sierra, Jussi Tohka, Olli Gröhn, Asla
Publikováno v:
Biomedicines; Volume 10; Issue 11; Pages: 2721
It is necessary to develop reliable biomarkers for epileptogenesis and cognitive impairment after traumatic brain injury when searching for novel antiepileptogenic and cognition-enhancing treatments. We hypothesized that a multiparametric magnetic re
Publikováno v:
Journal of Computer Assisted Learning. 37:1409-1422
Previous evaluation studies have rarely used authentic online texts and investigated upper secondary school students' use of evaluation criteria and deep reasoning. The associations between internet-specific epistemic justifications for knowing and c
Autor:
Eppu, Manninen, Karthik, Chary, Riccardo, De Feo, Elina, Hämäläinen, Pedro, Andrade, Tomi, Paananen, Alejandra, Sierra, Jussi, Tohka, Olli, Gröhn, Asla, Pitkänen
It is necessary to develop reliable biomarkers for epileptogenesis and cognitive impairment after traumatic brain injury when searching for novel antiepileptogenic and cognition-enhancing treatments. We hypothesized that a multiparametric magnetic re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::259273eb07d3bd71dbbe4f7d6b318e06
https://hdl.handle.net/11573/1670674
https://hdl.handle.net/11573/1670674