Výsledky vyhledávání - "Elin S. Agoston"

Akademický článek

Gene expression signature of normal cell-of-origin predicts ovarian tumor outcomes.

Autor: Melissa A Merritt, Stefan Bentink, Matthew Schwede, Marcin P Iwanicki, John Quackenbush, Terri Woo, Elin S Agoston, Ferenc Reinhardt, Christopher P Crum, Ross S Berkowitz, Samuel C Mok, Abigail E Witt, Michelle A Jones, Bin Wang, Tan A Ince

Publikováno v: PLoS ONE, Vol 8, Iss 11, p e80314 (2013)

The potential role of the cell-of-origin in determining the tumor phenotype has been raised, but not adequately examined. We hypothesized that distinct cells-of-origin may play a role in determining ovarian tumor phenotype and outcome. Here we descri

Externí odkaz: https://doaj.org/article/72352486e23d439e8ed96457071ba73e

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Akademický článek

Taurolidine antiadhesive properties on interaction with E. coli; its transformation in biological environment and interaction with bacteria cell wall.

Autor: Francesco Caruso, James W Darnowski, Cristian Opazo, Alexander Goldberg, Nina Kishore, Elin S Agoston, Miriam Rossi

Publikováno v: PLoS ONE, Vol 5, Iss 1, p e8927 (2010)

The taurine amino-acid derivative, taurolidine, bis-(1,1-dioxoperhydro-1,2,4-thiabiazinyl-4)methane, shows broad antibacterial action against gram-positive and gram-negative bacteria, mycobacteria and some clinically relevant fungi. It inhibits, in v

Externí odkaz: https://doaj.org/article/a22ca908fce543519b12ea468f0a21d9

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Abstract 337: A metastatic phenotype is reproduced in spheroids containing patient-specific cancer cells and mesenchymal stem cells

Autor: Amit Shahar, David Deems, Dmitry Shvartsman, Elin S. Agoston, Amy Pepicelli, Liam Deems

Publikováno v: Cancer Research. 80:337-337

Reproducible, scalable, and patient-specific 3D models of the tumor microenvironment are required to study tumor growth, metastasis and dormancy. In this study, patient-derived cancer cells, mesenchymal stem cells (MSCs), and optimization of the oxyg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a7eb3de9825c9b40e8772761f0829922
https://doi.org/10.1158/1538-7445.am2020-337

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Abstract 1054: Genomic representation of metastatic breast cancer patients by commercially available cell lines

Autor: Elin S. Agoston, Pamela Shaw, Agoston T. Agoston, Naghmeh Salimi, Rick Nicoletti

Publikováno v: Cancer Research. 78:1054-1054

We probed the clinicopathologic context of commercially available cell lines using sequencing data from the recently released Metastatic Breast Cancer (MBC) Project. Additionally, we identified cohorts in the MBC with similar profiles to the Wood cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d676bab103800a0bb80a024e677bca41
https://doi.org/10.1158/1538-7445.am2018-1054

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P16 Immunostaining Patterns in Microglandular Hyperplasia of the Cervix and Their Significance

Autor: Christopher P. Crum, Chandler Birch, Michael H. Roh, Elin S. Agoston

Publikováno v: International Journal of Gynecological Pathology. 28:107-113

P16 immunostaining is an important adjunct in the differential diagnosis of difficult squamous and glandular intraepithelial lesions of the cervix. However, unexpected staining of epithelium other than the target lesion can pose a problem in the inte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64d3e7eb9cc8dc313440859a8c458e14
https://doi.org/10.1097/pgp.0b013e3181877a73

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Low-Calcemic, Highly Antiproliferative, 1-Difluoromethyl Hybrid Analogs of the Natural Hormone 1α,25-Dihydroxyvitamin D3: Design, Synthesis, and Preliminary Biological Evaluation

Autor: Byung Chul Suh, Thomas W. Kensler, Elin S. Agoston, Sara Peleg, Patrick M. Dolan, Gary H. Posner, Kimberly S. Petersen

Publikováno v: Journal of Medicinal Chemistry. 49:7513-7517

Replacing the 1alpha-OH group of the natural hormone 1alpha,25-dihydroxyvitamin D(3) (calcitriol) by a 1alpha-CHF(2) group and incorporating a potentiating side chain produced two new hybrid analogs 6 and 7. Both of these two hybrid analogs are as tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eb65e8e37af663745bd3a30f14b69c2
https://doi.org/10.1021/jm0609925

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Vitamin D Analogs as Anti-Carcinogenic Agents

Autor: Mark A. Hatcher, Gary H. Posner, Thomas W. Kensler, Elin S. Agoston

Publikováno v: Anti-Cancer Agents in Medicinal Chemistry. 6:53-71

Deltanoids are the class of compounds comprising all natural and synthetic vitamin D molecules. The anti-proliferative, pro-differentiation, and pro-apoptotic properties of deltanoids have garnered interest in the fields of cancer chemoprevention and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10aa69cf99d731e84f604344431f7802
https://doi.org/10.2174/187152006784111369

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