Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Elin M. V. Söderberg"'
Autor:
Henrik Jespersen, Mattias F. Lindberg, Marco Donia, Elin M. V. Söderberg, Rikke Andersen, Ulrich Keller, Lars Ny, Inge Marie Svane, Lisa M. Nilsson, Jonas A. Nilsson
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Combining different types of immune therapies might benefit certain patients. Here, the authors develop an autologous immune-humanized melanoma mouse model that allows the preclinical assessment of cancer cell–T cell interactions from each individu
Externí odkaz:
https://doaj.org/article/872053043156473e8e20cc09cdc48cb0
Autor:
Elin M. V. Söderberg, Claudia Mateoiu, Karin Sundfeldt, Per Karlsson, Elisabeth Werner Rönnerman, Toshima Z. Parris, Anikó Kovács, Jana Biermann, Hanna Engqvist, Khalil Helou
Publikováno v:
Oncotarget
Ovarian cancer is the most lethal gynecological malignancy in the western world. Despite recent efforts to characterize ovarian cancer using molecular profiling, few targeted treatment options are currently available. Here, we examined genetic varian
Autor:
Lars Ny, Elin M. V. Söderberg, Jonas Nilsson, Mattias F. Lindberg, Inge Marie Svane, Rikke Andersen, Henrik Jespersen, Lisa M. Nilsson, Marco Donia, Ulrich Keller
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Nature Communications
Jespersen, H, Lindberg, M F, Donia, M, Söderberg, E M V, Andersen, R, Keller, U, Ny, L, Svane, I M, Nilsson, L M & Nilsson, J A 2017, ' Clinical responses to adoptive T-cell transfer can be modeled in an autologous immune-humanized mouse model ', Nature Communications, vol. 8, 707 . https://doi.org/10.1038/s41467-017-00786-z
Nature Communications
Jespersen, H, Lindberg, M F, Donia, M, Söderberg, E M V, Andersen, R, Keller, U, Ny, L, Svane, I M, Nilsson, L M & Nilsson, J A 2017, ' Clinical responses to adoptive T-cell transfer can be modeled in an autologous immune-humanized mouse model ', Nature Communications, vol. 8, 707 . https://doi.org/10.1038/s41467-017-00786-z
Immune checkpoint inhibitors and adoptive cell transfer (ACT) of autologous tumor-infiltrating T cells have shown durable responses in patients with melanoma. To study ACT and immunotherapies in a humanized model, we have developed PDXv2.0 — a mela
Autor:
Göran Landberg, Paul A. Fitzpatrick, Elin M. V. Söderberg, Nina Akrap, G J Thomson, Hannah Harrison
Publikováno v:
SLAS Discovery. 22:827-836
In order to identify novel treatment principles specifically affecting cancer stem cells in triple-negative breast cancer, we have developed a high-throughput screening method based on the mammosphere and anoikis resistance assays allowing us to scre
Autor:
Mattias F. Lindberg, Thomas Helleday, Olof Wallner, Henrik Jespersen, Louise Carstam, Siggeir F. Brynjolfsson, Ulrika Stierner, Martin Scobie, Joakim Karlsson, Lars Ny, Elisa Funck-Brentano, Ulrika Warpman Berglund, Erik Larsson, Berglind Osk Einarsdottir, Elin M. V. Söderberg, Roger Olofsson Bagge, Jonas Nilsson, Tobias Koolmeister, Lisa M. Nilsson
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 9, Iss 8, Pp 1-12 (2018)
Cell Death and Disease, Vol 9, Iss 8, Pp 1-12 (2018)
Karonudib (TH1579) is a novel compound that exerts anti-tumor activities and has recently entered phase I clinical testing. The aim of this study was to conduct a pre-clinical trial in patient-derived xenografts to identify the possible biomarkers of