Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Elin M. Matsson"'
Autor:
Johan E. Palm, Lars Knutson, Anna Lundahl, Pernilla Bottner, Elin M. Matsson, Hans Lennernäs, Ulf Eriksson
Publikováno v:
Drug Metabolism and Disposition. 39:239-246
Ketoconazole has been shown in clinical trials to increase the plasma exposure of the oral anticoagulant prodrug AZD0837 [(2S)-N-{4- [(Z)-amino(methoxyimino)methyl]benzyl}-1-{(2R)-2-[3-chloro-5-(difluoromethoxy)phenyl]-2-hydroxyethanoyl}-azetidine-2-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::253c2f57e1cd658edfb198993b327f97
https://doi.org/10.1124/dmd.110.035022
https://doi.org/10.1124/dmd.110.035022
Publikováno v:
The Journal of Clinical Pharmacology. 50:1039-1049
The effect of a single intrajejunal dose of gemfibrozil (600 mg) on the plasma pharmacokinetics and biliary excretion of a single intrajejunal dose of rosuvastatin (20 mg) was investigated by using a multichannel catheter positioned in the distal duo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3199d3f4303aab408102756d60c2f8a6
https://doi.org/10.1177/0091270009357432
https://doi.org/10.1177/0091270009357432
Autor:
Lars Knutson, Per Artursson, Kajs-Marie Schützer, Marie Brännström, Hans Lennernäs, Maria Karlgren, Ulf Eriksson, Elin M. Matsson, Susanne Johansson, Kristina Dunér, Lucia Lazorova, Johan E. Palm, Anja Ekdahl
Publikováno v:
Molecular pharmaceutics. 10(11)
Two clinical trials and a large set of in vitro transporter experiments were performed to investigate if the hepatobiliary disposition of the direct thrombin inhibitor prodrug AZD0837 is the mechanism for the drug-drug interaction with ketoconazole o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed8a8f16d58cab5c285af97a6f670228
https://pubmed.ncbi.nlm.nih.gov/24079718
https://pubmed.ncbi.nlm.nih.gov/24079718
Autor:
Ulf Eriksson, Niclas Petri, Kurt-Jürgen Hoffmann, Elin M. Matsson, Lars Knutson, Hans Lennernäs, Patrik Fridblom, Ulrika Logren
Publikováno v:
Journal of clinical pharmacology. 51(5)
The biliary excretion of the oral thrombin inhibitor ximelagatran and its metabolites was investigated by using duodenal aspiration in healthy volunteers following intraintestinal dosing. In the first investigation, radiolabeled [(14)C]ximelagatran w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebb4f3050dd6be5f6b43022fa38496b9
https://pubmed.ncbi.nlm.nih.gov/20663994
https://pubmed.ncbi.nlm.nih.gov/20663994