Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Elin Lõhmussaar"'
Genetic Diversity in German and European Populations: Looking for Substructures and Genetic Patterns
Autor:
Elin Lõhmussaar, Jakob C. Mueller, Thomas Meitinger, Heinz Erich Wichmann, Michael Steffens, Claudia Lamina
Publikováno v:
Das Gesundheitswesen. 67:127-131
A classical case-control study is a powerful and cost-efficient approach to detect association of genetic markers with complex disease phenotypes. However, only a small fraction of significant association results has been replicated by other studies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffaf26f9e3cb462b7f1ed0832287291d
https://doi.org/10.1055/s-2005-858254
https://doi.org/10.1055/s-2005-858254
Autor:
Thomas Bettecken, Jakob C. Mueller, Anthony Gaddi, Stefan Schreiber, Peter Lichtner, Peter P. Pramstaller, Reedik Mägi, Alessandra Testa, Heinz-Erich Wichmann, Thomas Meitinger, Saskia Biskup, Elin Lõhmussaar, Thomas Illig, Arne Pfeufer, Irene Pichler, Jan Luedemann, Maido Remm, Andres Metspalu, Giovanni Romeo
Publikováno v:
Am. J. Hum. Genet. 76, 387-398 (2005)
The pattern of linkage disequilibrium (LD) is critical for association studies, in which disease-causing variants are identified by allelic association with adjacent markers. The aim of this study is to compare the LD patterns in several distinct Eur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4379580155830105df1665e57eb6adad
https://doi.org/10.1086/427925
https://doi.org/10.1086/427925
Autor:
Jakob C. Mueller, Gerhard F. Hamann, Erich Wichmann, Thomas Meitinger, Martin Dichgans, Elin Lõhmussaar, Tõnis Org, Andreas Gschwendtner
Publikováno v:
Stroke. 36(4)
Background and Purpose— Recent evidence has implicated the genes for 5-lipoxygenase activating protein ( ALOX5AP ) and phosphodiesterase 4D ( PDE4D ) as susceptibility genes for stroke in the Icelandic population. The aim of the present study was t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73f6c73f656a1bfb689374b4355675bb
https://pubmed.ncbi.nlm.nih.gov/15731479
https://pubmed.ncbi.nlm.nih.gov/15731479
Autor:
S. R. Seaman, N. Kern, Bertram Müller-Myhsok, Tim M. Strom, Brigitta Bondy, Florian Holsboer, Thomas C. Baghai, Peter Zill, Manfred Uhr, Peter Lichtner, Thomas Meitinger, Tanja Brückl, Heike E. Künzel, Susanne Lucae, Daria Salyakina, Thomas Messer, Benno Pütz, Roselind Lieb, Sieglinde Modell, Andrea Pfennig, G. M. Wochnik, Oliver Köhnlein, Jakob C. Mueller, J. Brunner, Hildegard Pfister, Sergi Papiol, B. Fuchs, M. Majer, Theo Rein, N. Müller, Elin Lõhmussaar, Thomas Bettecken, Rainer Rupprecht, Elisabeth B. Binder, Thomas Nickel, Martin A. Kohli, Heike Dabitz, Tobias Deiml, Marcus Ising
Publikováno v:
Nature genetics. 36(12)
The stress hormone-regulating hypothalamic-pituitary-adrenal (HPA) axis has been implicated in the causality as well as the treatment of depression. To investigate a possible association between genes regulating the HPA axis and response to antidepre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4baf2c0249fbf4b42dec5f83b629c243
https://pubmed.ncbi.nlm.nih.gov/15565110
https://pubmed.ncbi.nlm.nih.gov/15565110
Autor:
Lon R. Cardon, Susan F. Kirby, Tarmo Puurand, Jagjit Pabial, Sarah E. Hunt, Maido Remm, David Beare, Richard Mott, Ian Dunham, Rocky Ganske, Reedik Mägi, Elisabeth Dawson, Elin Lõhmussaar, Kate Rice, Emma Tinsley, Jaak Vilo, Yuan Chen, Panos Deloukas, Simon Livingstone, Gonçalo R. Abecasis, Ants Kurg, Andres Metspalu, Jana Zernant, Thomas Dibling, Neeme Tõnisson, Marianna Papaspyridonos, Suzannah Bumpstead, David R. F. Carter, David R. Bentley
Publikováno v:
Nature. 418(6897)
DNA sequence variants in specific genes or regions of the human genome are responsible for a variety of phenotypes such as disease risk or variable drug response. These variants can be investigated directly, or through their non-random associations w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96288ced3a97c417f0f36d08b0abbfb0
http://ora.ox.ac.uk/objects/uuid:ca9c0ceb-c3bf-4892-ac59-9c5896981ec9
http://ora.ox.ac.uk/objects/uuid:ca9c0ceb-c3bf-4892-ac59-9c5896981ec9
Publikováno v:
Scopus-Elsevier
We have developed a method for arrayed primer extension (APEX) on an oligonucleotide microchip together with the 4-color fluoresence imaging equipment and supporting software, that allows analysis of the DNA sequence and changes in it. Mutation analy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c193e11c5cabfe03620936d295b9bc99
https://pubmed.ncbi.nlm.nih.gov/10834405
https://pubmed.ncbi.nlm.nih.gov/10834405
Publikováno v:
Nature Genetics. 23:62-63
We describe an integrated genetic testing system consisting of DNA oligonucleotide array production, template preparation, multiplex primer extension on the array, fluorescence imaging equipment and data analysis. DNA oligonucleotide (ON) arrays are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::add8c43d79f4b987665765c35ea8d0d9
https://doi.org/10.1038/14366
https://doi.org/10.1038/14366