Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Elin Holmedal"'
Autor:
Nigel Davies, Daniel Hovdal, Nicholas Edmunds, Peter Nordberg, Anders Dahlén, Aleksandra Dabkowska, Marianna Yanez Arteta, Aurel Radulescu, Tomas Kjellman, Andreas Höijer, Frank Seeliger, Elin Holmedal, Elisabeth Andihn, Nils Bergenhem, Ann-Sofie Sandinge, Camilla Johansson, Leif Hultin, Marie Johansson, Johnny Lindqvist, Liselotte Björsson, Yujia Jing, Stefano Bartesaghi, Lennart Lindfors, Shalini Andersson
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 24, Iss , Pp 369-384 (2021)
Lipid nanoparticles (LNPs) are the most clinically advanced delivery system for RNA-based drugs but have predominantly been investigated for intravenous and intramuscular administration. Subcutaneous administration opens the possibility of patient se
Externí odkaz:
https://doaj.org/article/0ab815ddadcf443ab6a9364825393a93
Autor:
Camilla Johansson, Johnny Lindqvist, Lennart Lindfors, Peter Nordberg, Andreas Höijer, Elin Holmedal, Ann-Sofie Sandinge, Marianna Yanez Arteta, Anders Dahlén, Yujia Jing, Elisabeth Andihn, Aurel Radulescu, Leif Hultin, Nicholas Edmunds, Shalini Andersson, Frank Seeliger, Daniel Hovdal, Nils Bergenhem, Nigel Davies, Aleksandra P. Dabkowska, Liselotte Björsson, Stefano Bartesaghi, Tomas Kjellman, Marie Johansson
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 24, Iss, Pp 369-384 (2021)
Molecular Therapy. Nucleic Acids
Molecular Therapy / Nucleic Acids 24, 369-384 (2021). doi:10.1016/j.omtn.2021.03.008
Molecular Therapy. Nucleic Acids
Molecular Therapy / Nucleic Acids 24, 369-384 (2021). doi:10.1016/j.omtn.2021.03.008
Lipid nanoparticles (LNPs) are the most clinically advanced delivery system for RNA-based drugs but have predominantly been investigated for intravenous and intramuscular administration. Subcutaneous administration opens the possibility of patient se
Autor:
Paul R. Hansen, Bernard D Hummel, Elin Holmedal, Jeffrey L. Watts, Johan Svenson, Håvard Jenssen, Natalia Molchanova, Joakim Håkansson, Ines Greco
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Greco, I, Molchanova, N, Holmedal, E, Jenssen, H, Hummel, B D, Watts, J L, Håkansson, J, Hansen, P R & Svenson, J 2020, ' Correlation between hemolytic activity, cytotoxicity and systemic in vivo toxicity of synthetic antimicrobial peptides ', Scientific Reports, vol. 10, 13206 . https://doi.org/10.1038/s41598-020-69995-9
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Greco, I, Molchanova, N, Holmedal, E, Jenssen, H, Hummel, B D, Watts, J L, Håkansson, J, Hansen, P R & Svenson, J 2020, ' Correlation between hemolytic activity, cytotoxicity and systemic in vivo toxicity of synthetic antimicrobial peptides ', Scientific Reports, vol. 10, 13206 . https://doi.org/10.1038/s41598-020-69995-9
The use of non-standard toxicity models is a hurdle in the early development of antimicrobial peptides towards clinical applications. Herein we report an extensive in vitro and in vivo toxicity study of a library of 24 peptide-based antimicrobials wi