Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Elimelech Nesher"'
Autor:
Hadas Fulman-Levy, Raichel Cohen-Harazi, Bar Levi, Lital Argaev-Frenkel, Ifat Abramovich, Eyal Gottlieb, Sarah Hofmann, Igor Koman, Elimelech Nesher
Publikováno v:
Cancer & Metabolism, Vol 12, Iss 1, Pp 1-15 (2024)
Abstract Background The ketogenic diet (KD), based on high fat (over 70% of daily calories), low carbohydrate, and adequate protein intake, has become popular due to its potential therapeutic benefits for several diseases including cancer. Under KD a
Externí odkaz:
https://doaj.org/article/41cfb44736a84ddfb0cdc90807d349c3
Autor:
Katerina V. Gurova, Jianmin Wang, Igor Koman, Eunice S. Wang, Scott Portwood, Ieman Aljahdali, Alfiya Safina, Elimelech Nesher
Precisely how DNA-targeting chemotherapeutic drugs trigger cancer cell death remains unclear, as it is difficult to separate direct DNA damage from other effects in cells. Recent work on curaxins, a class of small-molecule drugs with broad anticancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f7a904f82ce3e12092940ee1993cfdb
https://doi.org/10.1158/0008-5472.c.6510777
https://doi.org/10.1158/0008-5472.c.6510777
Autor:
Katerina V. Gurova, Jianmin Wang, Igor Koman, Eunice S. Wang, Scott Portwood, Ieman Aljahdali, Alfiya Safina, Elimelech Nesher
File contains the list of all chemicals, reagents, antibodies and cells used with sources and catalogue numbers, as well as detailed description of all methods, mentioned in the in the main text, including cytotoxicity assays, imaging, cell-free expe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7c10c5084098c1c11dc545adedfd379
https://doi.org/10.1158/0008-5472.22420875.v1
https://doi.org/10.1158/0008-5472.22420875.v1
Autor:
Tzachy Morad, Roni Mina Hendler, Eyal Canji, Orly Eva Weiss, Guy Sion, Refael Minnes, Ania Hava Grushchenko Polaq, Ido Merfeld, Zvy Dubinsky, Elimelech Nesher, Danny Baranes
Publikováno v:
Polymers, Vol 12, Iss 12, p 2850 (2020)
Biomaterials, especially when coated with adhesive polymers, are a key tool for restorative medicine, being biocompatible and supportive for cell adherence, growth, and function. Aragonite skeletons of corals are biomaterials that support survival an
Externí odkaz:
https://doaj.org/article/3a3cde0399a84a58877c5bd43dfd5150
Publikováno v:
Cancer Research. 83:6044-6044
Tumors are heterogeneous, consisting of different cell subpopulations to allow tumor survival in variable conditions. We observed the survival of a small percentage of HCT116 cells under glucose starvation. We hypothesized that these cells represent
Autor:
Katerina Leonova, Alfiya Safina, Elimelech Nesher, Poorva Sandlesh, Rachel Pratt, Catherine Burkhart, Brittany Lipchick, Ilya Gitlin, Costakis Frangou, Igor Koman, Jianmin Wang, Kirill Kirsanov, Marianna G Yakubovskaya, Andrei V Gudkov, Katerina Gurova
Publikováno v:
eLife, Vol 7 (2018)
Cellular responses to the loss of genomic stability are well-established, while how mammalian cells respond to chromatin destabilization is largely unknown. We previously found that DNA demethylation on p53-deficient background leads to transcription
Externí odkaz:
https://doaj.org/article/88616e07b80f41b895f651a4e32753ab
Autor:
Debpali Sur, Katerina Leonova, Bar Levi, Shany Ivon Markowitz, Raichel Cohen-Harazi, Ilya Gitlin, Katerina Gurova, Andrei Gudkov, Albert Pinhasov, Igor Koman, Elimelech Nesher
Publikováno v:
International journal of molecular sciences. 23(13)
Interferon (IFN) signaling resulting from external or internal inflammatory processes initiates the rapid release of cytokines and chemokines to target viral or bacterial invasion, as well as cancer and other diseases. Prolonged exposure to IFNs, or
Publikováno v:
Cancer Research. 82:3016-3016
The ketogenic diet, based on high fat (over 70% of daily calories), low carbohydrate, and adequate protein intake, has become popular due to its potential therapeutic benefits for several diseases including cancer. Recent evidence suggests ketogenic
Autor:
Gulshara Abildinova, Zhanara Abdrakhmanova, Helena Tuchinsky, Elimelech Nesher, Albert Pinhasov, Leon Raskin
Publikováno v:
Genetics and Molecular Biology, Iss 0 (2016)
Abstract The routine detection of large and medium copy number variants (CNVs) is well established. Hemizygotic deletions or duplications in the large Duchenne muscular dystrophy DMD gene responsible for Duchenne and Becker muscular dystrophies are r
Externí odkaz:
https://doaj.org/article/5b97f7a7a9d14d72b1900235d7b93209
Autor:
Elimelech Nesher, Bar Levi, Michael Kirby, Maria Becker, Albert Pinhasov, Igor Koman, Shiri Yacobovich, Boris Redko, Gary Gellerman, Oryan Agranyoni
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 17
International Journal of Molecular Sciences, Vol 22, Iss 9579, p 9579 (2021)
Volume 22
Issue 17
International Journal of Molecular Sciences, Vol 22, Iss 9579, p 9579 (2021)
We examined the effects of ALOS4, a cyclic peptide discovered previously by phage library selection against integrin αvβ3, on a human melanoma (A375) xenograft model to determine its abilities as a potential anti-cancer agent. We found that ALOS4 p