Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Elijus Undzys"'
Autor:
Eno Hysi, Lauren A. Wirtzfeld, Jonathan P. May, Elijus Undzys, Shyh-Dar Li, Michael C. Kolios
Publikováno v:
Photoacoustics, Vol 5, Iss C, Pp 25-35 (2017)
Frequency analysis of the photoacoustic radiofrequency signals and oxygen saturation estimates were used to monitor the in-vivo response of a novel, thermosensitive liposome treatment. The liposome encapsulated doxorubicin (HaT-DOX) releasing it rapi
Externí odkaz:
https://doaj.org/article/d3b205d7ba404d2781161da256caf2b9
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0174076 (2017)
[This corrects the article DOI: 10.1371/journal.pone.0165345.].
Externí odkaz:
https://doaj.org/article/16324c259e5148a09832bfc9fe2206c1
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0165345 (2016)
Imaging methods capable of indicating the potential for success of an individualized treatment course, during or immediately following the treatment, could improve therapeutic outcomes. Temperature Sensitive Liposomes (TSLs) provide an effective way
Externí odkaz:
https://doaj.org/article/9eb35ff97d794b20b06d65c40701c7aa
Autor:
Ahmed Mamai, Anh M. Chau, Brian J. Wilson, Iain D. Watson, Babu B. Joseph, Pandiaraju R. Subramanian, Monzur M. Morshed, Justin A. Morin, Michael A. Prakesch, Tianbao Lu, Pete Connolly, Douglas A. Kuntz, Neil C. Pomroy, Gennady Poda, Kong Nguyen, Richard Marcellus, Graig Strathdee, Brigitte Theriault, Ratheesh Subramaniam, Mohammed Mohammed, Ayome Abibi, Manuel Chan, Jeffrey Winston, Taira Kiyota, Elijus Undzys, Ahmed Aman, Nigel Austin, Marc Du Jardin, Kathryn Packman, Ulrike Phillippar, Riccardo Attar, James Edwards, Jeff O’Meara, David E. Uehling, Rima Al-awar, Gilbert G. Privé, Methvin B. Isaac
Publikováno v:
ACS Medicinal Chemistry Letters. 14:199-210
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7baafefe694004e06c601f99ee7e496
https://doi.org/10.1021/acsmedchemlett.2c00502
https://doi.org/10.1021/acsmedchemlett.2c00502
Autor:
Shugang Yao, Hiba Zahreddine, Amit Subedi, Liying Gong, Amogh Nair, Alex Zhou, Tiffany Cheng, Elijus Undzys, Dominic Hou, Lucy Lai, Luis A. Da Cruz, David Young
Publikováno v:
Cancer Research. 83:2931-2931
Trophoblast cell surface antigen-2 (TROP2) is a membrane-bound protein expressed during development and at lower levels in normal adult tissues. In many solid tumors TROP2 upregulation is associated with increased tumor aggressiveness, metastasis, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f16d7dde14bb4b16d9b526c11d7377e
https://doi.org/10.1158/1538-7445.am2023-2931
https://doi.org/10.1158/1538-7445.am2023-2931
Autor:
Israel Matos, Yahya Ashraf, Hiba Zahreddine, Liying Gong, Amanda Baumholtz, Alex Zhou, Claire Bonfils, Aniel Moya-Torres, Yun Cui, Xiaowei Wang, Richard Wargachuk, Tiffany Cheng, Elijus Undzys, Shugang Yao, Jacynthe Linda Tolouse, Dominic Hou, Gordon Ngan, Luis daCruz, David Young
Publikováno v:
Cancer Research. 82:324-324
Trophoblast cell surface antigen-2 (TROP2) is a membrane-bound protein expressed during development and at lower levels in normal adult tissues. TROP2 has pleiotropic functions including formation of cell-cell junctions by mediating interactions with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f5cb492f0d64b0c09d23275a1282dca
https://doi.org/10.1158/1538-7445.am2022-324
https://doi.org/10.1158/1538-7445.am2022-324
Autor:
Shugang Yao, Yun Cui, Anna Kazanats, Liying Gong, Claire Bonfils, Dominic Hou, Emily Chen, Elijus Undzys, Jacynthe Toulouse, Milica Krstic, Hiba Zahreddine, Israel Matos, Alex Zhou, Aniel Moya-Torres, Richard Wargachuk, Carl Gay, Lauren Byers, Gordon Ngan, Luis da Cruz, David Young
Publikováno v:
Molecular Cancer Therapeutics. 20:P200-P200
We developed a single domain VHH multi-specific antibody format. Multispecific antibodies have multiple mechanisms of action which may work independently or together, to achieve better clinical outcomes in cancers with high unmet medical need such as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d83789dabf462ca192cf11db27ed02dc
https://doi.org/10.1158/1535-7163.targ-21-p200
https://doi.org/10.1158/1535-7163.targ-21-p200
Autor:
Milica Krstic, Morin Nicolas, Jacynthe L. Toulouse, Shugang Yao, Dominic Hou, David Young, Claire Bonfils, Yun Cui, Luis A. G. Dacruz, Donald Gagné, Elijus Undzys, Ashwani K. Gupta, Emily I. Chen, Alex Zhou, Richard Wargachuk
Publikováno v:
Cancer Research. 81:LB094-LB094
Monoclonal antibody therapy has revolutionized cancer treatment by addressing a variety of mechanisms from interfering with signaling to checkpoint inhibition. Bispecific antibodies double the number of therapeutic mechanisms addressed by each antibo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::386713aba29efc679bbf49f695cb289c
https://doi.org/10.1158/1538-7445.am2021-lb094
https://doi.org/10.1158/1538-7445.am2021-lb094
Publikováno v:
Bioconjugate Chemistry. 28:1505-1518
Polymer conjugation is an attractive approach for delivering insoluble and highly toxic drugs to tumors. However, most reports in the literature only disclose the optimal composition without emphasizing rational design or composition optimization to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d74e0fda952616ffe6fca2958bec55a2
https://doi.org/10.1021/acs.bioconjchem.7b00165
https://doi.org/10.1021/acs.bioconjchem.7b00165
Publikováno v:
Pharmaceutical Research. 33:1104-1114
This study was aimed at developing a new active loading method to stably encapsulate staurosporine (STS), a water insoluble drug, into lipid-based nanoparticles (LNPs) for drug targeting to tumors. A limited amount of DMSO was included during the act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::318d31b74f6deec2d568630e68229abc
https://doi.org/10.1007/s11095-015-1854-4
https://doi.org/10.1007/s11095-015-1854-4