Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Elijahu Berkovich"'
Autor:
Bendix Labeit, Elijahu Berkovich, Inga Claus, Malte Roderigo, Anna-Lena Schwake, Dvora Izgelov, Dorit Mimrod, Sigrid Ahring, Stephan Oelenberg, Paul Muhle, Verena Zentsch, Fiona Wenninger, Sonja Suntrup-Krueger, Rainer Dziewas, Tobias Warnecke
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-8 (2022)
Abstract Dysphagia is common in Parkinson’s disease (PD) and is assumed to complicate medication intake. This study comprehensively investigates dysphagia for medication and its association with motor complications in PD. Based on a retrospective a
Externí odkaz:
https://doaj.org/article/2a4daef685964af188120033d84f9e05
Autor:
Géraldine H Petit, Elijahu Berkovich, Mark Hickery, Pekka Kallunki, Karina Fog, Cheryl Fitzer-Attas, Patrik Brundin
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60691 (2013)
Impaired olfaction is an early pre-motor symptom of Parkinson's disease. The neuropathology underlying olfactory dysfunction in Parkinson's disease is unknown, however α-synuclein accumulation/aggregation and altered neurogenesis might play a role.
Externí odkaz:
https://doaj.org/article/e8efaf418dac492aae7ce80a13b31c39
Autor:
Adagio investigators, Rom E. Eliaz, Arun K. Tiwari, Elijahu Berkovich, James L. Kennedy, Shannon Collinson, Iris Grossman, Maria Tampakeras, Cheryl Fitzer-Attas, Amir Tchelet, Jo Knight, Mario Masellis, Natalie Freeman, Anthony E. Lang, Victor Abler, Joseph Levy, Eli Eyal, Michael R. Hayden
Publikováno v:
Brain. 139:2050-2062
The treatment of early Parkinson's disease with dopaminergic agents remains the mainstay of symptomatic therapy for this incurable neurodegenerative disorder. However, clinical responses to dopaminergic drugs vary substantially from person to person
Autor:
Michael B. Kastan, Elijahu Berkovich
Publikováno v:
Nature Cell Biology. 9:489-491
p53 is usually referred to as a commonly altered tumour suppressor gene. A new study supports a decade of accumulating evidence that mutated p53 protein can gain new functions and also behave as an oncogene. This study specifically suggests that cert
Publikováno v:
Parkinsonismrelated disorders. 20(6)
Background The ADAGIO study included a large cohort of patients with early PD (baseline total-UPDRS = 20) who were initially randomized to rasagiline and placebo, thereby allowing analyses of symptomatic efficacy. Methods Post-hoc analyses comparing
Publikováno v:
Nature protocols. 3(5)
The formation of protein aggregates (foci) at sites of DNA double-strand breaks (DSBs) is mainly studied by immunostaining and is hence limited by the low resolution of light microscopy and the availability of appropriate and selective antibodies. He
Publikováno v:
Journal of virology. 82(14)
Genomic instability, a hallmark of leukemic cells, is associated with malfunctioning cellular responses to DNA damage caused by defective cell cycle checkpoints and/or DNA repair. Adult T-cell leukemia, which can result from infection with human T-ce
Publikováno v:
Nature cell biology. 9(6)
We developed a novel system to create DNA double-strand breaks (DSBs) at defined endogenous sites in the human genome, and used this system to detect protein recruitment and loss at and around these breaks by chromatin immunoprecipitation (ChIP). The