Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Elijah Genetzakis"'
Autor:
Weiqian E. Lee, Marie Besnier, Elijah Genetzakis, Owen Tang, Katharine A. Kott, Stephen T. Vernon, Michael P. Gray, Stuart M. Grieve, Michael Kassiou, Gemma A. Figtree
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 22 (2023)
Improved human-relevant preclinical models of coronary artery disease (CAD) are needed to improve translational research and drug discovery. Mitochondrial dysfunction and associated oxidative stress contribute to endothelial dysfunction and are a sig
Externí odkaz:
https://doaj.org/article/6c38c99fec4345bbb0d31db51d4056fb
Autor:
Katharine A. Kott, Elijah Genetzakis, Michael P. Gray, Peter Hansen, Helen M. McGuire, Jean Y. Yang, Stuart M. Grieve, Stephen T. Vernon, Gemma A. Figtree
Publikováno v:
Biomolecules, Vol 13, Iss 8, p 1187 (2023)
Risk-factor-based scoring systems for atherosclerotic coronary artery disease (CAD) remain concerningly inaccurate at the level of the individual and would benefit from the addition of biomarkers that correlate with atherosclerosis burden directly. W
Externí odkaz:
https://doaj.org/article/e41e7fd4fd31493d8967924070904f7f
Publikováno v:
Antioxidants, Vol 12, Iss 7, p 1359 (2023)
Although elevated cholesterol and other recognised cardiovascular risk factors are important in the development of coronary artery disease (CAD) and heart attack, the susceptibility of humans to this fatal process is distinct from other animals. Mito
Externí odkaz:
https://doaj.org/article/10cc690adc754a48968dc2896a6bc67e
Autor:
Marie Besnier, Meghan Finemore, Christine Yu, Katharine A. Kott, Stephen T. Vernon, Nicole A. Seebacher, Elijah Genetzakis, Anamarija Furman, Owen Tang, Ryan L. Davis, Thomas Hansen, Peter J. Psaltis, Kristen J. Bubb, Steven G. Wise, Stuart M. Grieve, Belinda A. Di Bartolo, Gemma A. Figtree
Publikováno v:
Antioxidants, Vol 10, Iss 10, p 1547 (2021)
Mechanisms involved in the individual susceptibility to atherosclerotic coronary artery disease (CAD) beyond traditional risk factors are poorly understood. Here, we describe the utility of cultured patient-derived endothelial colony-forming cells (E
Externí odkaz:
https://doaj.org/article/219ff944593b4fc89e0f82d1c15aff5a
Publikováno v:
Pharmacologytherapeutics. 237
The purinoceptor 7 receptor (P2X
Publikováno v:
SSRN Electronic Journal.
Autor:
Gemma A. Figtree, Steven G. Wise, Christine Yu, Stephen T Vernon, Belinda A. Di Bartolo, Stuart M. Grieve, Meghan Finemore, Katharine A Kott, Anamarija Furman, Owen Tang, Kristen J. Bubb, Peter J. Psaltis, Elijah Genetzakis, Ryan L. Davis, Thomas Hansen, Marie Besnier, Nicole A. Seebacher
Publikováno v:
Antioxidants
Volume 10
Issue 10
Antioxidants, Vol 10, Iss 1547, p 1547 (2021)
Volume 10
Issue 10
Antioxidants, Vol 10, Iss 1547, p 1547 (2021)
Mechanisms involved in the individual susceptibility to atherosclerotic coronary artery disease (CAD) beyond traditional risk factors are poorly understood. Here, we describe the utility of cultured patient-derived endothelial colony-forming cells (E
Autor:
Belinda A. Di Bartolo, Meghan Finemore, Gemma A. Figtree, Elijah Genetzakis, Marie Besnier, Owen Tang
Publikováno v:
Circulation. 142
Micro-RNAs (miRs) are small non-coding RNAs that alter the expression of multiple mRNA targets. Although they participate in physiological processes, dysregulation of their expression is implicated in various diseases. We investigated whether miRs co
Autor:
Marie Besnier, Thomas Hansen, Gemma A. Figtree, Michael Tsang, Meghan Finemore, Keyvan Karimi Galougahi, James O'Brien-Brown, Elijah Genetzakis, Kristen J. Bubb, Michael Kassiou, Belinda A. Di Bartolo
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 319(1)
This study demonstrates the therapeutic potential for right-sided heart failure of a novel inhibitor of the P2X7 receptor (P2X7R). Inflammatory signaling and right ventricular function were improved in a mouse model of pulmonary fibrosis with seconda