Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Elijah D. Johnston"'
Autor:
Andrew C Melton, Jennifer Melrose, Liisa Alajoki, Sylvie Privat, Hannah Cho, Naomi Brown, Ana Marija Plavec, Dat Nguyen, Elijah D Johnston, Jian Yang, Mark A Polokoff, Ivan Plavec, Ellen L Berg, Alison O'Mahony
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58966 (2013)
Improper regulation of B cell responses leads to excessive production of antibodies and contributes to the development of autoimmune disease. T helper 17 (Th17) cells also drive the development of autoimmune disease, but the role of B cells in shapin
Externí odkaz:
https://doaj.org/article/b2a1465f63034f5fb3cebec00bc94e27
Autor:
Christopher R. Burtner, Brian A. Kudlow, Brian K. Kennedy, Elijah D. Johnston, Monique N. Stanfel
Publikováno v:
Molecular Biology of the Cell. 19:5238-5248
Hutchinson-Gilford progeria syndrome (HGPS) is a rare, debilitating disease with early mortality and rapid onset of aging-associated pathologies. It is linked to mutations in LMNA, which encodes A-type nuclear lamins. The most frequent HGPS-associate
Autor:
Erica D. Smith, Mitsuhiro Tsuchiya, Nick Dang, Di Hu, Matt Kaeberlein, Diana N. Pak, James H. Thomas, Lindsay A. Fox, Daniel E. L. Promislow, Brian K. Kennedy, Emily O. Kerr, Elijah D. Johnston, K. Linnea Welton, Bie N. Tchao
Publikováno v:
Genome Research. 18:564-570
Studies in invertebrate model organisms have been a driving force in aging research, leading to the identification of many genes that influence life span. Few of these genes have been examined in the context of mammalian aging, however, and it remain
Autor:
Brady Olsen, Marc K. Ting, Simon C. Johnson, Annie Chou, Dennis Wang, Monika Jelic, Zhongjun Zhou, Dillon Pruett, Eric C. Liao, Sarani Goswami, Mitsuhiro Tsuchiya, Ariana A. Rodriguez, Arieanna C. Anies, Theodor K. Bammler, Elroy H. An, Sylvia Sim, Diana N. Pak, Kristan K. Steffen, Juniper K. Pennypacker, Kim M. Pham, Christopher F. Bennett, Helen Vander Wende, Richard M. Moller, Bopharoth Ros, Tom Pollard, Richard P. Beyer, Mark A. McCormick, Winston Lo, Joe R. Delaney, Jennifer Schleit, Shannon Klum, Diana Kim, Anthony S. Castanza, Rachel B. Brem, Ki Soo Jeong, Benjamin L. Spector, Daniel B. Carr, Brian M. Wasko, K. Linnea Welton, Eric A. Westman, Donna Prunkard, Scott Tsuchiyama, Katie Kirkland, Amrita Solanky, Dilreet Rai, Shiena Enerio, Christopher J. Murakami, Manpreet K. Singh, Marissa Fletcher, Anna Shemorry, George L. Sutphin, Elijah D. Johnston, Molly A. Holmberg, Zhao Jun Peng, Lindsay A. Fox, Sean Higgins, Yousin Suh, Michael Lim, Dan Lockshon, Jin Kim, Jessica Hui, Erica D. Smith, Eunice Choi, Brian Muller, Xinguang Liu, Soumya Kotireddy, Nick Dang, Hillary Miller, Prarthana Pradeep, Di Hu, Brett Robison, Brian K. Kennedy, Matt Kaeberlein, Katie Snead, Michael Sage, Emily O. Kerr, Michael S. Lin, Umema Ahmed, Bie N. Tchao, Jonathan A. Oakes, Adrienne M. Wang
Publikováno v:
Cell metabolism. 22(5)
SummaryMany genes that affect replicative lifespan (RLS) in the budding yeast Saccharomyces cerevisiae also affect aging in other organisms such as C. elegans and M. musculus. We performed a systematic analysis of yeast RLS in a set of 4,698 viable s
Autor:
Nick Dang, Brian K. Kennedy, Matt Kaeberlein, Lindsay A. Fox, Vivian L. MacKay, Jonathan A. Oakes, Emily O. Kerr, Stanley Fields, Diana N. Pak, Mitsuhiro Tsuchiya, Bie N. Tchao, Di Hu, Elijah D. Johnston, Kristan K. Steffen
Publikováno v:
Cell. (2):292-302
SummaryIn nearly every organism studied, reduced caloric intake extends life span. In yeast, span extension from dietary restriction is thought to be mediated by the highly conserved, nutrient-responsive target of rapamycin (TOR), protein kinase A (P