Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Elif Nihal Korkmaz"'
Publikováno v:
PLoS Computational Biology, Vol 8, Iss 3, p e1002420 (2012)
The KIX domain of CBP is a transcriptional coactivator. Concomitant binding to the activation domain of proto-oncogene protein c-Myb and the transactivation domain of the trithorax group protein mixed lineage leukemia (MLL) transcription factor lead
Externí odkaz:
https://doaj.org/article/1fb6dc56d9d04f95aa7387e28e2c1974
Autor:
Susana Vázquez Torres, Philip J. Y. Leung, Isaac D. Lutz, Preetham Venkatesh, Joseph L. Watson, Fabian Hink, Huu-Hien Huynh, Andy Hsien-Wei Yeh, David Juergens, Nathaniel R. Bennett, Andrew N. Hoofnagle, Eric Huang, Michael J MacCoss, Marc Expòsit, Gyu Rie Lee, Paul M. Levine, Xinting Li, Mila Lamb, Elif Nihal Korkmaz, Jeff Nivala, Lance Stewart, Joseph M. Rogers, David Baker
Many peptide hormones form an alpha-helix upon binding their receptors1–4, and sensitive detection methods for them could contribute to better clinical management.De novoprotein design can now generate binders with high affinity and specificity to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1f71e8af52449b591ee281d1a65d41b
https://doi.org/10.1101/2022.12.10.519862
https://doi.org/10.1101/2022.12.10.519862
Autor:
Devesh Bhimsaria, Qiang Cui, Parameswaran Ramanathan, José A. Rodríguez-Martínez, Aseem Z. Ansari, Junkun Pan, Elif Nihal Korkmaz, Daniel Roston
Publikováno v:
Proceedings of the National Academy of Sciences. 115
We have developed Differential Specificity and Energy Landscape (DiSEL) analysis to comprehensively compare DNA-protein interactomes (DPIs) obtained by high-throughput experimental platforms and cutting edge computational methods. While high-affinity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9582ab51f4aa683b33fd68322b48061
https://doi.org/10.1073/pnas.1811431115
https://doi.org/10.1073/pnas.1811431115
Autor:
Gregory D. Kennedy, Qiang Cui, Manabu Nukaya, Lisa Burdette, Vitali Stanevich, Yongna Xing, Elif Nihal Korkmaz, Kenneth A. Satyshur, Christopher A. Bradfield, Li Jiang
Publikováno v:
Toxicological Sciences. 129:86-97
The aryl hydrocarbon receptor (AHR) is a transcription factor that responds to diverse ligands and plays a critical role in toxicology, immune function, and cardiovascular physiology. The structural basis of the AHR for ligand promiscuity and prefere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66b93db32e60f6d52cf66d6c9922de6b
https://doi.org/10.1093/toxsci/kfs194
https://doi.org/10.1093/toxsci/kfs194
Skip residues modulate the structural properties of the myosin rod and guide thick filament assembly
Autor:
Leslie A. Leinwand, Ada Buvoli, Ivan Rayment, Keenan C. Taylor, Massimo Buvoli, Yuqing Zheng, Nathan T. Heinze, Qiang Cui, Elif Nihal Korkmaz
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 112(29)
The rod of sarcomeric myosins directs thick filament assembly and is characterized by the insertion of four skip residues that introduce discontinuities in the coiled-coil heptad repeats. We report here that the regions surrounding the first three sk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63f30127ff722562c2efdeee61a79bcb
https://pubmed.ncbi.nlm.nih.gov/26150528
https://pubmed.ncbi.nlm.nih.gov/26150528
Publikováno v:
The journal of physical chemistry. B. 119(30)
The human lymphotactin (hLtn) is a protein that features two native states both of which are physiologically relevant: it is a monomer (hLtn10) at 10 °C with 200 mM salt and a dimer (hLtn40) at 40 °C and without salt. Here we focus on the networks
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::504f74dd241265e75a5d110138b8cda9
https://pubmed.ncbi.nlm.nih.gov/26134347
https://pubmed.ncbi.nlm.nih.gov/26134347
Publikováno v:
PLoS Computational Biology, Vol 8, Iss 3, p e1002420 (2012)
PLoS Computational Biology
PLoS Computational Biology
The KIX domain of CBP is a transcriptional coactivator. Concomitant binding to the activation domain of proto-oncogene protein c-Myb and the transactivation domain of the trithorax group protein mixed lineage leukemia (MLL) transcription factor lead
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6227077fca00f769dcecf79d2b5bc201
http://europepmc.org/articles/PMC3305381?pdf=render
http://europepmc.org/articles/PMC3305381?pdf=render
Publikováno v:
Journal of Physical Chemistry B; Jul2015, Vol. 119 Issue 30, p9547-9558, 12p