Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Eliezer Shochat"'
Autor:
David Johnson, Anthony J. Connor, Steve McKeever, Zhihui Wang, Thomas S. Deisboeck, Tom Quaiser, Eliezer Shochat
Publikováno v:
Cancer Informatics, Vol 2014, Iss Suppl. 1, Pp 133-143 (2014)
Externí odkaz:
https://doaj.org/article/3c17407ffae6410dbbc1e8b2815f88f9
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10010 (2010)
Bacterial infections occur when the natural host defenses are overwhelmed by invading bacteria. The main component of the host defense is impaired when neutrophil count or function is too low, putting the host at great risk of developing an acute inf
Externí odkaz:
https://doaj.org/article/e90dc04d5bc6444db6e72d6c47521cca
Autor:
Wilfried Ernst Erich Eberhardt, Jan H.M. Schellens, Valerie Meresse Naegelen, Steve Blotner, Eliezer Shochat, Jean J.L. Tessier, Ruediger Rueger, Zhi-Xin Xu, Vanesa Lopez-Valverde, Avinash Gupta, Max E. Scheulen, Veronique Dieras, Françoise Kraeber-Bodéré, Patricia Tresca, Mark R. Middleton, Suzanne Leijen
PDF file, 1001K, Methods; Supplementary Table 1 - Temporary dose interruptions due to adverse events; Supplementary Table 2 - Changes in biomarker levels between baseline and Day 15; Supplementary Figure 1: Schematic showing dosing cohorts, DLTs and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d7be86e7d7ff6abbb2f08c3c8e17ccc
https://doi.org/10.1158/1078-0432.22452476.v1
https://doi.org/10.1158/1078-0432.22452476.v1
Autor:
Jean-Charles Soria, Valerie Meresse Naegelen, Steve Blotner, Eliezer Shochat, Jean J. L. Tessier, Ruediger Rueger, Zhi-Xin Xu, Ernesto Guarin, Emilie Routier, Federico Rojo, Françoise Kraeber-Bodéré, Saoirse Dolly, Rastilav Bahleda, Joan Albanell, Udai Banerji, Maria Martinez-Garcia
PDF file, 130K.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::006b8947be1db4b35cb0c1be9eb3d2ac
https://doi.org/10.1158/1078-0432.22451105.v1
https://doi.org/10.1158/1078-0432.22451105.v1
Autor:
Vered Rom-Kedar, Eliezer Shochat
Supplementary Data from Novel Strategies for Granulocyte Colony-Stimulating Factor Treatment of Severe Prolonged Neutropenia Suggested by Mathematical Modeling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab924c157bbf2e082784a762f792494d
https://doi.org/10.1158/1078-0432.22439701.v1
https://doi.org/10.1158/1078-0432.22439701.v1
Autor:
Jean-Charles Soria, Valerie Meresse Naegelen, Steve Blotner, Eliezer Shochat, Jean J. L. Tessier, Ruediger Rueger, Zhi-Xin Xu, Ernesto Guarin, Emilie Routier, Federico Rojo, Françoise Kraeber-Bodéré, Saoirse Dolly, Rastilav Bahleda, Joan Albanell, Udai Banerji, Maria Martinez-Garcia
Purpose: This phase I study assessed the maximum tolerated dose (MTD), dose-limiting toxicities (DLT), safety, pharmacokinetics, pharmacodynamics, and clinical activity of the first-in-class dual MEK/RAF inhibitor, RO5126766.Experimental Design: Init
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbca345e19eeb5455a74ad1913cfe943
https://doi.org/10.1158/1078-0432.c.6522101
https://doi.org/10.1158/1078-0432.c.6522101
Autor:
Jean-Charles Soria, Valerie Meresse Naegelen, Steve Blotner, Eliezer Shochat, Jean J. L. Tessier, Ruediger Rueger, Zhi-Xin Xu, Ernesto Guarin, Emilie Routier, Federico Rojo, Françoise Kraeber-Bodéré, Saoirse Dolly, Rastilav Bahleda, Joan Albanell, Udai Banerji, Maria Martinez-Garcia
PDF file, 18K, Schematic showing cohort doses evaluated, dose-limiting-toxicities observed and maximum-tolerated-doses per dosing regimen.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b59472046794d1c2b3578f6cc4e14ad1
https://doi.org/10.1158/1078-0432.22451108.v1
https://doi.org/10.1158/1078-0432.22451108.v1
Autor:
Jean-Charles Soria, Valerie Meresse Naegelen, Steve Blotner, Eliezer Shochat, Jean J. L. Tessier, Ruediger Rueger, Zhi-Xin Xu, Ernesto Guarin, Emilie Routier, Federico Rojo, Françoise Kraeber-Bodéré, Saoirse Dolly, Rastilav Bahleda, Joan Albanell, Udai Banerji, Maria Martinez-Garcia
PDF file, 9K, Summary of pharmacokinetics of RO4987655 in patients following oral administration.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::088e1989b219d8b25cb6ff3d615e9d0d
https://doi.org/10.1158/1078-0432.22451102.v1
https://doi.org/10.1158/1078-0432.22451102.v1
Autor:
Vered Rom-Kedar, Eliezer Shochat
Purpose: To improve the effectiveness of granulocyte colony-stimulating factor (G-CSF) treatment in high-risk neutropenic patients.Experimental Design: We study G-CSF effects on chemotherapy-induced neutropenia by expanding a simple mathematical mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03562fe997b29331e8bac05c58552be6
https://doi.org/10.1158/1078-0432.c.6517132
https://doi.org/10.1158/1078-0432.c.6517132
Autor:
Wilfried Ernst Erich Eberhardt, Jan H.M. Schellens, Valerie Meresse Naegelen, Steve Blotner, Eliezer Shochat, Jean J.L. Tessier, Ruediger Rueger, Zhi-Xin Xu, Vanesa Lopez-Valverde, Avinash Gupta, Max E. Scheulen, Veronique Dieras, Françoise Kraeber-Bodéré, Patricia Tresca, Mark R. Middleton, Suzanne Leijen
Purpose: This phase I study of the mitogen-activated protein/extracellular signal–regulated kinase inhibitor RO4987655 (CH4987655) assessed its maximum tolerated dose (MTD), dose-limiting toxicities (DLT), safety, pharmacokinetic/pharmacodynamic pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ff974d06dbf6f4cb720dc587268b045
https://doi.org/10.1158/1078-0432.c.6522491
https://doi.org/10.1158/1078-0432.c.6522491