Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Eliezer Rapaport"'
Autor:
Guido Guidotti, Eliezer Rapaport, Edward H Abraham, Ellen D Waitzkin, Andrew Donnelly, Kent Robinson, Robert J. Griffin, Kenon Qamar, David Bower, Jack Brown, Sukumar Ethirajan, Mark A Thompson
Publikováno v:
Purinergic Signalling
Systemic pools of ATP are elevated in individuals homozygous for cystic fibrosis (CF) as evidenced by elevated blood and plasma ATP levels. This elevated ATP level seems to provide benefit in the presence of advanced solid tumors (Abraham et al., Nat
The pharmacokinetics of adenosine 5′-triphosphate (ATP) was investigated in a clinical trial that included 15 patients with advanced malignancies (solid tumors). ATP was administered by continuous intravenous infusions of 8 h once weekly for 8 week
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6601c229cfbc1ca64af7b793747b1a79
https://europepmc.org/articles/PMC4425716/
https://europepmc.org/articles/PMC4425716/
Autor:
Eliezer Rapaport
Publikováno v:
Expert Opinion on Investigational Drugs. 3:379-389
Preclinical animal studies as well as recent clinical Phase I studies have demonstrated that organ, total blood (red blood cells) and blood plasma compartment pools (steady state levels) of adenosine 5'-triphosphate can be readily increased by admini
Autor:
Eliezer Rapaport
Publikováno v:
Drug Development Research. 28:428-431
The utilization of adenosine 5'-triphosphate (ATP) infusions against solid refractory cancers is based on the preclinical findings that low levels of extracellular ATP significantly inhibit the growth of a variety of human and murine tumor cells. The
Publisher Summary This chapter discusses the three properties of intravenously administered adenosine triphosphate (ATP) that contribute to its efficacy and are expected to significantly affect the outcomes of patients with advanced cancer. The three
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04f4d2a6c62978dfc674760770b29cf8
https://doi.org/10.1016/s1063-5823(03)01013-5
https://doi.org/10.1016/s1063-5823(03)01013-5
Autor:
John W. Babich, David R. Elmaleh, Artiom Petrov, Paul C. Zamecnik, Alan J. Fischman, Ban-An Khaw, Jagat Narula, Eliezer Rapaport
The development of a noninvasive imaging procedure for identifying atherosclerotic lesions is extremely important for the clinical management of patients with coronary artery and peripheral vascular disease. Although numerous radiopharmaceuticals hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d58ab41de35f4469b0db657aeb974df
https://europepmc.org/articles/PMC18482/
https://europepmc.org/articles/PMC18482/
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 93(2)
Strains of Mycobacterium smegmatis, a mycobacterium which shares genetic sequences, grows more rapidly, and is nonpathogenic in man as compared with Mycobacterium tuberculosis, were utilized for the initial development of new antimycobacterial therap
Autor:
Eliezer Rapaport
Publikováno v:
American journal of therapeutics. 2(4)
Non-insulin-dependent diabetes mellitus (NIDDM) is a heterogeneous disease resulting primarily from a variety of pancreatic beta-cell disorders and insulin resistance. Whereas insulin resistance, which constitutes a defect in insulin action, increase
The possible involvement of protein phosphorylation in the clostridial stress response was investigated by radioactively labeling growing cells of Clostridium acetobutylicum with {sup 32}P{sub i} or cell extracts with ({gamma}-{sup 32}P)ATP. Several
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::329d45c497ade4faf922b067548322b0
https://europepmc.org/articles/PMC184578/
https://europepmc.org/articles/PMC184578/
Publikováno v:
Proceedings of the National Academy of Sciences. 78:838-842
The purified high molecular weight form of HeLa cell DNA polymerase alpha (deoxynucleosidetriphosphate: DNA deoxynucleotidyltransferase, EC 2.7.7.7) was shown to associate tightly with several aminoacyl-tRNA synthetase activities. Fractionation of th