Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Eliezer Ortiz"'
Autor:
Michael J. Krische, Eliezer Ortiz, Connor Saludares, Jessica Wu, Yoon Cho, Catherine G. Santana
Publikováno v:
Synthesis. 55:1487-1496
The evolution of methods for carbonyl allylation and crotylation of alcohol proelectrophiles culminating in the design of iodide-bound ruthenium-JOSIPHOS catalysts is prefaced by a brief historical perspective on asymmetric carbonyl allylation and it
Publikováno v:
ACS Catalysis. 13:1662-1668
Publikováno v:
ACS Catalysis. 12:8164-8174
Publikováno v:
J Am Chem Soc
The first enantioselective ruthenium-catalyzed carbonyl vinylations via hydrogen auto-transfer are described. Using a ruthenium-JOSIPHOS catalyst, primary alcohols 2a-2m and 2-butyne 1a are converted to chiral allylic alcohols 3a-3m with excellent le
Publikováno v:
Angewandte Chemie International Edition. 62
Publikováno v:
Chemical Science. 13:12625-12633
Ruthenium-catalyzed hydrogen auto-transfer reactions for the direct enantioselective conversion of lower alcohols to higher alcohols are surveyed. These processes enable completely atom-efficient carbonyl addition from alcohol proelectrophiles in the
Publikováno v:
Organic letters.
The site-selective functionalization of unactivated allylic C-H bonds via direct deprotonation using KTMP is described. The conversion of amorphadiene to artemisinic alcohol via a simple, highly regioselective deprotonation over 4 other possible ally
Publikováno v:
Angewandte Chemie. 134
Iodide-bound ruthenium-JOSIPHOS complexes catalyze the redox-neutral C-C coupling of primary alcohols with methylallene (1,2-butadiene) or 1,3-butadiene to form products of anti-crotylation with good to excellent levels of diastereo- and enantioselec
Autor:
Eliezer Ortiz, Jonathan Z Shezaf, Yu-Hsiang Chang, Michael J. Krische, Kuo-Wei Huang, Théo P. Gonçalves
Publikováno v:
J Am Chem Soc
Crystallographic characterization of RuX(CO)(η(3)-C(3)H(5))(JOSIPHOS), where X = Cl, Br, I, reveals a halide-dependent diastereomeric preference that defines metal-centered stereogenicity and, therefrom, the enantioselectivity of C-C coupling in rut
Publikováno v:
Chem Rev
Catalytic reductive coupling of enone, acrylate or vinyl heteroaromatic pronucleophiles with carbonyl or imine partners offers an alternative to base-mediated enolization in aldol and Mannich type reactions. In this monograph, direct catalytic reduct