Zobrazeno 1 - 10
of 1 141
pro vyhledávání: '"Eliezer Masliah"'
Autor:
Michiyo Iba, Somin Kwon, Changyoun Kim, Marcell Szabo, Liam Horan-Portelance, Maria Lopez-Ocasio, Pradeep Dagur, Cassia Overk, Robert A. Rissman, Eliezer Masliah
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-16 (2024)
Abstract The neuroinflammatory process in synucleinopathies of the aging population such as Parkinson’s disease (PD) and dementia with Lewy bodies (DLB) involves microglial activation as well as infiltration of the CNS by T cells and natural killer
Externí odkaz:
https://doaj.org/article/c8ac0709bc0142fc94ad06c7597d1500
Autor:
Natalia Cecilia Prymaczok, Pablo Nicolas De Francesco, Samanta Mazzetti, Marie Humbert-Claude, Liliane Tenenbaum, Graziella Cappelletti, Eliezer Masliah, Mario Perello, Roland Riek, Juan Atilio Gerez
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-18 (2024)
Abstract Parkinson’s disease is characterized by a progressive accumulation of alpha-Synuclein (αSyn) neuronal inclusions called Lewy bodies in the nervous system. Lewy bodies can arise from the cell-to-cell propagation of αSyn, which can occur v
Externí odkaz:
https://doaj.org/article/b475e19f60dc407d997399ffc8c7268c
Publikováno v:
Prion, Vol 17, Iss 1, Pp 29-34 (2023)
ABSTRACTAlthough multiple sclerosis (MS) and multiple system atrophy (MSA) are both characterized by impaired oligodendrocytes (OLs), the aetiological relevance remains obscure. Given inherent stressors affecting OLs, the objective of the present stu
Externí odkaz:
https://doaj.org/article/4831f26d22c4496f94908cedac05dd43
Autor:
Mathew Blurton-Jones, Brian Spencer, Sara Michael, Nicholas A. Castello, Andranik A. Agazaryan, Joy L. Davis, Franz-Josef Müller, Jeanne F. Loring, Eliezer Masliah, Frank M. LaFerla
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/a8f7f613f4364215aed3a6cbb63b15c4
Autor:
Brian Spencer, Ivy Trinh, Edward Rockenstein, Michael Mante, Jazmin Florio, Anthony Adame, Omar M.A. El-Agnaf, Changyoun Kim, Eliezer Masliah, Robert A. Rissman
Publikováno v:
Neurobiology of Disease, Vol 191, Iss , Pp 106397- (2024)
Externí odkaz:
https://doaj.org/article/73d77c89544648b3b03a844465b7f0f9
Autor:
André D.G. Leitão, Rijwan U. Ahammad, Brian Spencer, Chengbiao Wu, Eliezer Masliah, Robert A. Rissman
Publikováno v:
Neurobiology of Disease, Vol 186, Iss , Pp 106285- (2023)
Neurodegenerative disorders of aging are characterized by the progressive accumulation of proteins such as α-synuclein (α-syn) and amyloid beta (Aβ). Misfolded and aggregated α-syn has been implicated in neurological disorders such as Parkinson's
Externí odkaz:
https://doaj.org/article/94d42ccc67b4462b801ed0ceabf727e0
Autor:
Mohamed Bilal Fares, Omar Alijevic, Stephanie Johne, Cassia Overk, Makoto Hashimoto, Athanasios Kondylis, Anthony Adame, Remi Dulize, Dariusz Peric, Catherine Nury, James Battey, Emmanuel Guedj, Nicolas Sierro, Damian Mc Hugh, Edward Rockenstein, Changyoun Kim, Robert A. Rissman, Julia Hoeng, Manuel C. Peitsch, Eliezer Masliah, Carole Mathis
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
IntroductionAlpha-synuclein (α-Syn) aggregation, transmission, and contribution to neurotoxicity represent central mechanisms underlying Parkinson’s disease. The plant alkaloid “nicotine” was reported to attenuate α-Syn aggregation in differe
Externí odkaz:
https://doaj.org/article/eae8ebe4bbe94ac488d6544ea8c9efeb
Autor:
Michiyo Iba, Ross A. McDevitt, Changyoun Kim, Roshni Roy, Dimitra Sarantopoulou, Ella Tommer, Byron Siegars, Michelle Sallin, Somin Kwon, Jyoti Misra Sen, Ranjan Sen, Eliezer Masliah
Publikováno v:
Molecular Neurodegeneration, Vol 17, Iss 1, Pp 1-23 (2022)
Abstract Background Although ɑ-synuclein (ɑ-syn) spreading in age-related neurodegenerative diseases such as Parkinson’s disease (PD) and Dementia with Lewy bodies (DLB) has been extensively investigated, the role of aging in the manifestation of
Externí odkaz:
https://doaj.org/article/670f9acba7aa433e8bb59b55b6e0626d
Autor:
Namjoon Cho, Jaegeon Joo, Sunkyung Choi, Bu-Gyeong Kang, Andrew J. Lee, So-Yeon Youn, Su-Hyung Park, Eun-Mi Kim, Eliezer Masliah, Yuji Ko, Sun-Shin Cha, Inkyung Jung, Kee K. Kim
Publikováno v:
Heliyon, Vol 9, Iss 3, Pp e14039- (2023)
Several studies have identified mutations in neuroprotective genes in a few cases of Parkinson's disease (PD); however, the role of alternative splicing changes in PD remains unelucidated. Based on the transcriptome analysis of substantia nigra (SN)
Externí odkaz:
https://doaj.org/article/4b9006d5a8814af790553007ee3c8493
Autor:
Suzhen Lin, André D.G. Leitão, Savannah Fang, Yingli Gu, Sophia Barber, Rhiannon Gilliard-Telefoni, Alfredo Castro, Kijung Sung, Ruinan Shen, Jazmin B. Florio, Michael L. Mante, Jianqing Ding, Brian Spencer, Eliezer Masliah, Robert A. Rissman, Chengbiao Wu
Publikováno v:
Neurobiology of Disease, Vol 178, Iss , Pp 106010- (2023)
Mutations or triplication of the alpha synuclein (ASYN) gene contribute to synucleinopathies including Parkinson's disease (PD), Dementia with Lewy bodies (DLB) and multiple system atrophy (MSA). Recent evidence suggests that ASYN also plays an impor
Externí odkaz:
https://doaj.org/article/ce172def23994913ad183ff932d3046b