Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Eliezer Jager"'
Autor:
Maria Camilla Operti, Alexander Bernhardt, Jeanette Pots, Vladimir Sincari, Eliezer Jager, Silko Grimm, Andrea Engel, Anne Benedikt, Martin Hrubý, Ingrid Jolanda M. De Vries, Carl G. Figdor, Oya Tagit
Publikováno v:
Pharmaceutics, Vol 14, Iss 8, p 1690 (2022)
Poly(lactic-co-glycolic acid) (PLGA) nanoparticle-based drug delivery systems are known to offer a plethora of potential therapeutic benefits. However, challenges related to large-scale manufacturing, such as the difficulty of reproducing complex for
Externí odkaz:
https://doaj.org/article/5ada7c51945c412bbfb6796f958649f0
Autor:
Maria Camilla Operti, Alexander Bernhardt, Vladimir Sincari, Eliezer Jager, Silko Grimm, Andrea Engel, Martin Hruby, Carl Gustav Figdor, Oya Tagit
Publikováno v:
Pharmaceutics, Vol 14, Iss 2, p 276 (2022)
Despite the efficacy and potential therapeutic benefits that poly(lactic-co-glycolic acid) (PLGA) nanomedicine formulations can offer, challenges related to large-scale processing hamper their clinical and commercial development. Major hurdles for th
Externí odkaz:
https://doaj.org/article/520ea29edb634f44a4939dd9f2d92bf8
Autor:
Fernando A. de Oliveira, Carin C. S. Batista, Lindomar J. C. Albuquerque, Peter Černoch, Miloš Steinhart, Vladimir Sincari, Alessandro Jager, Eliezer Jager, Fernando C. Giacomelli
Publikováno v:
Journal of Colloid and Interface Science
The ability to tune size and morphology of self-assemblies is particularly relevant in the development of delivery systems. By tailoring such structural parameters, one can provide larger cargo spaces or produce nanocarriers that can be loaded by hyd
Publikováno v:
Colloid and Polymer Science. 294:1717-1726
1H NMR spectroscopy was used for the first time to investigate temperature behaviour of aqueous solutions of nanoparticles (NPs) prepared from linear and Y-shape terpolymers containing blocks of poly(ethylene oxide) (PEO), poly(2-ethyl-2-oxazoline) (
Autor:
Svetlana Lukáš Petrova, Martina Vragović, Ewa Pavlova, Zulfiya Černochová, Alessandro Jäger, Eliézer Jäger, Rafał Konefał
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1191 (2023)
This paper introduces a new class of amphiphilic block copolymers created by combining two polymers: polylactic acid (PLA), a biocompatible and biodegradable hydrophobic polyester used for cargo encapsulation, and a hydrophilic polymer composed of ol
Externí odkaz:
https://doaj.org/article/ab1ae1eed5b44f088388ebbc4139a8ca
Autor:
Klara Pecankova, Pavla Pecherkova, Zdenka Gasova, Zofie Sovova, Tomas Riedel, Eliézer Jäger, Jaroslav Cermak, Pavel Majek
Publikováno v:
PLoS ONE, Vol 17, Iss 1 (2022)
Background Extracellular vesicles are released into body fluids from the majority of, if not all, cell types. Because their secretion and specific cargo (e.g., proteins) varies according to pathology, extracellular vesicles may prove a rich source of
Externí odkaz:
https://doaj.org/article/11b90946a2fa49f9a3b238428ed6da86
Autor:
Yusuf Dölen, Uzi Gileadi, Ji-Li Chen, Michael Valente, Jeroen H. A. Creemers, Eric A. W. Van Dinther, N. Koen van Riessen, Eliezer Jäger, Martin Hruby, Vincenzo Cerundolo, Mustafa Diken, Carl G. Figdor, I. Jolanda M. de Vries
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Tumor-specific neoantigens can be highly immunogenic, but their identification for each patient and the production of personalized cancer vaccines can be time-consuming and prohibitively expensive. In contrast, tumor-associated antigens are widely ex
Externí odkaz:
https://doaj.org/article/0cd7f0771f6d416b8ca65394e4472b9d
Autor:
Yusuf Dölen, Michael Valente, Oya Tagit, Eliezer Jäger, Eric A. W. Van Dinther, N. Koen van Riessen, Martin Hruby, Uzi Gileadi, Vincenzo Cerundolo, Carl G. Figdor
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
Nanovaccines, co-delivering antigen and invariant natural killer T (iNKT) cell agonists, proved to be very effective in inducing anti-tumor T cell responses due to their exceptional helper function. However, it is known that iNKT cells are not equall
Externí odkaz:
https://doaj.org/article/c812d3d1313e4b30b8812dcd99efb274
Autor:
Eliana B. Souto, Eliézer Jäger, Alessandro Jäger, Petr Štěpánek, Amanda Cano, Cesar Viseras, Raquel de Melo Barbosa, Marlus Chorilli, Aleksandra Zielińska, Patricia Severino, Beatriz C. Naveros
Publikováno v:
Nanomaterials, Vol 12, Iss 3, p 377 (2022)
Despite the health benefits of the sun, overexposure to solar radiation without proper precautions can cause irreversible damage to exposed skin. In the search for balance between the risks and benefits of exposure to solar radiation in human health,
Externí odkaz:
https://doaj.org/article/04ebb126b0b64bf29be334529ad18606
Autor:
Svetlana Lukáš Petrova, Eliézer Jäger, Alessandro Jäger, Anita Höcherl, Rafał Konefał, Alexander Zhigunov, Ewa Pavlova, Olga Janoušková, Martin Hrubý
Publikováno v:
Polymers, Vol 13, Iss 9, p 1465 (2021)
Here, we report on the construction of biodegradable poly(ethylene oxide monomethyl ether) (MPEO)-b-poly(ε-caprolactone) (PCL) nanoparticles (NPs) having acid-labile (acyclic ketal group) linkage at the block junction. In the presence of acidic pH,
Externí odkaz:
https://doaj.org/article/3c3a5d1f5fbb4f7393a326fd97d28eda