Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Eliete S. Rodrigues"'
Autor:
Nara Sobreira, Kimberly F. Doheny, Shalini N. Jhangiani, Zeynep Coban-Akdemir, James R. Lupski, David Valle, Sean Griffith, Elizabeth Wohler, Eliete S. Rodrigues, Jennifer E. Posey, Corina Antonescu, Renan Paulo Martin, Ada Hamosh
Publikováno v:
Orphanet Journal of Rare Diseases
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-10 (2021)
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-10 (2021)
Background With the advent of whole exome (ES) and genome sequencing (GS) as tools for disease gene discovery, rare variant filtering, prioritization and data sharing have become essential components of the search for disease genes and variants poten
Autor:
Eliete S. Rodrigues, Laerte Oliveira, Suma I. Shimuta, Renan Paulo Martin, João Bosco Pesquero, Clovis R. Nakaie, Rafael Filippelli-Silva
Publikováno v:
Biological Chemistry. 397:305-314
Bradykinin (BK) is a nonapeptide important for several physiological processes such as vasodilatation, increase in vascular permeability and release of inflammatory mediators. BK performs its actions by coupling to and activating the B2 receptor, a f
Autor:
Eliete S. Rodrigues, Clovis R. Nakaie, Silvana Aparecida Alves Correa, Suzana M. Oliveira, Suma I. Shimuta, Renan Paulo Martin, Laerte Oliveira, Nelson A.S. Pacheco
Publikováno v:
Regulatory Peptides. 158:14-18
Previous studies on angiotensin II (AngII) AT(1) receptor function have revealed that the N-terminal residues of AngII may modulate receptor activation by binding at the receptor extracellular site. A remarkable feature of this site is an insertion o
Autor:
Renan Paulo Martin, Eliete S. Rodrigues, Clovis R. Nakaie, Suma I. Shimuta, Rafael Filippelli-Silva
Publikováno v:
Journal of pharmacological and toxicological methods. 79
Angiotensin II (AngII) and kinins (bradykinin (BK) and des-Arg9-bradykinin (DBK)), are potent agents involved in the maintenance of blood pressure and several biological activities, and their better understanding is important to produce new drugs aim
Autor:
Suma I. Shimuta, Laerte Oliveira, Clovis R. Nakaie, Eliete S. Rodrigues, Renan Paulo Martin, Rafael Filippelli da Silva
Publikováno v:
Regulatory peptides. 181
Mutant forms of kinin B(1) receptor (B(1)R) and analogs of the full agonist des-Arg(9)-bradykinin (DABK) were investigated aiming to verify the importance of selected receptor residues and of each agonist-peptide residue in the specific binding and a
Autor:
Michael Bader, Suma I. Shimuta, Rafael Filippelli da Silva, Clovis R. Nakaie, Regiane A. Sabatini, Renan Paulo Martin, Eliete S. Rodrigues, Vanessa F. Merino, João Bosco Pesquero, Suzana M. Oliveira
Publikováno v:
Peptides. 42
Bradykinin (BK) and des-Arg 9 -bradykinin (DBK) of kallikrein-kinin system exert its effects mediated by the B 2 (B 2 R) and B 1 (B 1 R) receptors, respectively. It was already shown that the deletion of kinin B 1 R or of B 2 R induces upregulation o
Autor:
Suma I. Shimuta, Clovis R. Nakaie, Silvana Aparecida Alves Correa, Eliete S. Rodrigues, Renato A. Mortara, Laerte Oliveira, Renan Paulo Martin, Suzana M. Oliveira
Publikováno v:
Biological Chemistry. 391
Previous research showed that disruption of the Cys18-Cys274bond in the angiotensin II (AngII) AT1receptor mutant (C18S), expressed in CHO cells, causes an increase in the basal activity and attenuation of the maximum response to AngII. In addition,
Autor:
Suzana M. Oliveira, Renan Paulo Martin, Michael Bader, Suma I. Shimuta, Eliete S. Rodrigues, Sandra A. Felipe
Publikováno v:
Biological chemistry. 390(9)
Bradykinin (BK) is a vasorelaxant, algesic and inflammatory agent. Angiotensin II (AngII) is known to control vascular tone and promote growth, inflammation and artherogenesis. There is evidence for cross talking between BK and AngII receptors. There