Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Elie Maksoud"'
Publikováno v:
Cell Reports, Vol 26, Iss 7, Pp 1774-1786.e4 (2019)
Summary: Pathogenic mutations in leucine-rich repeat kinase 2 (LRRK2) induce an age-dependent loss of dopaminergic (DA) neurons. We have identified Furin 1, a pro-protein convertase, as a translational target of LRRK2 in DA neurons. Transgenic knockd
Externí odkaz:
https://doaj.org/article/151996a4837f4ca9b1958407794bafa2
Autor:
Tina A. Solvik, Alexandra M. Schnoes, Thi A. Nguyen, Shannon Behrman, Elie Maksoud, Sarah S. Goodwin, Ethan J. Weiss, Arun Padmanabhan, David N. Cornfield
ImportanceDespite the importance of clinician-scientists in propelling biomedical advances, the proportion of physicians engaged in both hypothesis-driven research and clinical care continues to decline. Recently, multiple institutions have developed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6635efa5576297a78563b12c1990bf8d
https://doi.org/10.1101/2022.12.19.22283532
https://doi.org/10.1101/2022.12.19.22283532
Autor:
Xiaoyu Tracy Cai, Stephen R. Quake, Yuxin Liang, Jovencio Borneo, Martin Borch Jensen, Pejmun Haghighi, Hongjie Li, Elie Maksoud, Liqun Luo, Heinrich Jasper
Publikováno v:
Nature
Infection-induced aversion against enteropathogens is a conserved sickness behaviour that can promote host survival1,2. The aetiology of this behaviour remains poorly understood, but studies in Drosophila have linked olfactory and gustatory perceptio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db7de570b8db33d4093ff1fecd4f87c4
https://doi.org/10.1038/s41586-021-03756-0
https://doi.org/10.1038/s41586-021-03756-0
Autor:
Mario R. Calderon, Megumi Mori, Grant Kauwe, Jill Farnsworth, Suzana Ulian-Benitez, Elie Maksoud, Jordan Shore, A. Pejmun Haghighi
Publikováno v:
Proceedings of the National Academy of Sciences. 119
While the role of barrier function in establishing a protective, nutrient-rich, and ionically balanced environment for neurons has been appreciated for some time, little is known about how signaling cues originating in barrier-forming cells participa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5602193c3183eaf77b682b654a0ca80c
https://doi.org/10.1073/pnas.2110097119
https://doi.org/10.1073/pnas.2110097119
Autor:
Mauricio Ortega, Ayano Harata, Amit Sharma, Kazutaka Akagi, Blaine Pattavina, Mark A. Watson, Kenneth A. Wilson, Elie Maksoud, Rachel B. Brem, Christopher S. Nelson, Pankaj Kapahi
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Exposure to genotoxic stress by environmental agents or treatments, such as radiation therapy, can diminish healthspan and accelerate aging. We have developed a Drosophila melanogaster model to study the molecular effects of radiation-induced damage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c018e20a68ca4f6ffc61c6baf2f71ed2
https://pubmed.ncbi.nlm.nih.gov/33154387
https://pubmed.ncbi.nlm.nih.gov/33154387
Autor:
Elie Maksoud, Amit Sharma, Pankaj Kapahi, Rachel B. Brem, Kazutaka Akagi, Mark A. Watson, Christopher S. Nelson, Mauricio Ortega, Kenneth A. Wilson, Blaine Pattavina
Exposure to genotoxic stress by environmental agents or treatments, such as radiation therapy, can diminish health span and accelerate aging. We have developed aDrosophila melanogastermodel to study the molecular effects of radiation-induced damage a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e26eccd653be6bcb4abc206df867535
https://doi.org/10.1101/540377
https://doi.org/10.1101/540377
Publikováno v:
Cell reports
Cell Reports, Vol 26, Iss 7, Pp 1774-1786.e4 (2019)
Cell Reports, Vol 26, Iss 7, Pp 1774-1786.e4 (2019)
SUMMARY Pathogenic mutations in leucine-rich repeat kinase 2 (LRRK2) induce an age-dependent loss of dopaminergic (DA) neurons. We have identified Furin 1, a pro-protein convertase, as a translational target of LRRK2 in DA neurons. Transgenic knockdo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1acaabd22937290f1ad1fedea514f93f
http://europepmc.org/articles/PMC6474846
http://europepmc.org/articles/PMC6474846
Autor:
Iman Haddad, Victoria Shilova, Trey Ideker, Yongsheng Guan, Joëlle Vinh, Kenichiro Ono, Yann Verdier, Elie Maksoud, Chieko Makino-Okamura, Michael Boutros, Charles Hetru, Jules A. Hoffmann, Xi Liu, Jun Matsubayashi, Jean Rossier, Kerstin Spirohn, Hidehiro Fukuyama
Publikováno v:
HAL
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2013
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2013, 110 (26), pp.10717-22. ⟨10.1073/pnas.1304380110⟩
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2013
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2013, 110 (26), pp.10717-22. ⟨10.1073/pnas.1304380110⟩
The Drosophila defense against pathogens largely relies on the activation of two signaling pathways: immune deficiency (IMD) and Toll. The IMD pathway is triggered mainly by Gram-negative bacteria, whereas the Toll pathway responds predominantly to G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe5cd87bd6dc64ef5dc12acb0a20535d
https://hal.archives-ouvertes.fr/hal-01659451
https://hal.archives-ouvertes.fr/hal-01659451