The genomic ancestry of individuals from different geographical regions of Brazil is more uniform than expected.

Autor: Sérgio D J Pena, Giuliano Di Pietro, Mateus Fuchshuber-Moraes, Julia Pasqualini Genro, Mara H Hutz, Fernanda de Souza Gomes Kehdy, Fabiana Kohlrausch, Luiz Alexandre Viana Magno, Raquel Carvalho Montenegro, Manoel Odorico Moraes, Maria Elisabete Amaral de Moraes, Milene Raiol de Moraes, Elida B Ojopi, Jamila A Perini, Clarice Racciopi, Andrea Kely Campos Ribeiro-Dos-Santos, Fabrício Rios-Santos, Marco A Romano-Silva, Vinicius A Sortica, Guilherme Suarez-Kurtz

Publikováno v: PLoS ONE, Vol 6, Iss 2, p e17063 (2011)

Based on pre-DNA racial/color methodology, clinical and pharmacological trials have traditionally considered the different geographical regions of Brazil as being very heterogeneous. We wished to ascertain how such diversity of regional color categor

Externí odkaz: https://doaj.org/article/47d5071fbd074d108b6a70080571e9a6

Clinical and biological predictors of Alzheimer's disease in patients with amnestic mild cognitive impairment Preditores clínicos e biológicos da evolução para doença de Alzheimer em pacientes com comprometimento cognitivo leve amnéstico

Autor: Orestes V. Forlenza, Breno S. Diniz, Leda L. Talib, Marcia Radanovic, Monica S. Yassuda, Elida B. Ojopi, Wagner F. Gattaz

Publikováno v: Brazilian Journal of Psychiatry, Vol 32, Iss 3, Pp 216-222 (2010)

OBJECTIVE: To identify predictors of the progression from pre-dementia stages of cognitive impairment in Alzheimer's disease is relevant to clinical management and to substantiate the decision of prescribing antidementia drugs. METHOD: Longitudinal s

Externí odkaz: https://doaj.org/article/1975bdb3526f469591ea657e66ae906a

Single-nucleotide polymorphisms of GSK3B, GAB2 and SORL1 in late-onset Alzheimer's disease: interactions with the APOE genotype

Autor: Daniel S. Kerr, Orestes Vicente Forlenza, Bernardo dos Santos, Wagner F. Gattaz, Elida B. Ojopi, Giselle Izzo, Paulo Henrique Ferreira Bertolucci

Publikováno v: Clinics, Vol 68, Iss 2, Pp 277-280 (2013)
Clinics, Volume: 68, Issue: 2, Pages: 277-280, Published: 2013
Clinics; v. 68 n. 2 (2013); 277-280
Clinics; Vol. 68 Núm. 2 (2013); 277-280
Clinics; Vol. 68 No. 2 (2013); 277-280
Clinics
Universidade de São Paulo (USP)
instacron:USP

In this study, we investigated the associations between single-nucleotide polymorphisms in GAB2 (rs2373115), GSK3B (rs6438552) and SORL1 (rs641120) and Alzheimer's disease (AD), both alone and in combination with the APOE*4 allele.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::946405ca0e221b669121dc532ea05605
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322013000200025

Epidermal growth factor receptor and KRAS mutations in Brazilian lung cancer patients

Autor: Heloisa Ciol, Luciana H. Silva, Elida B. Ojopi, Eduardo M. Queiroga, Carlos E. Bacchi, Lucimara C. Benine

Publikováno v: Clinics
Clinics; v. 67 n. 5 (2012); 419-424
Clinics; Vol. 67 Núm. 5 (2012); 419-424
Clinics; Vol. 67 No. 5 (2012); 419-424
Universidade de São Paulo (USP)
instacron:USP
Clinics, Vol 67, Iss 5, Pp 419-424 (2012)
Clinics, Volume: 67, Issue: 5, Pages: 419-424, Published: 2012

OBJECTIVE: Epidermal growth factor receptor is involved in the pathogenesis of non-small cell lung cancer and has recently emerged as an important target for molecular therapeutics. The KRAS oncogene also plays an important role in the development of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c52cbc4a48896fba85a529f0e14e450f
https://doi.org/10.6061/clinics/2012(05)03

SHORT COMMUNICATION: Apolipoprotein E genotype and Cognition in Bipolar Disorder

Autor: Elida B. Ojopi, Luis Felipe de Oliveira Costa, Doris Hupfeld Moreno, Ricardo Alberto Moreno, Vasco Videira Dias, Carolina Martins do Prado, Wagner F. Gattaz, Rodolfo Nunes Campos, Danielle Soares Bio, Márcio Gerhardt Soeiro de Souza

Publikováno v: CNS Neuroscience & Therapeutics. 16:316-321

Apolipoprotein E (APOE) has been extensively studied as a risk factor for sporadic and late onset Alzheimer's Disease (AD). APOE allele (∗)3, the most frequent variant, is not associated to cognitive dysfunction (CD) or to increased AD risk. Differ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::19a663ff2c22e196492bfc0ebe91e29e
https://doi.org/10.1111/j.1755-5949.2010.00153.x