Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Elice M. Brooks"'
Autor:
Bin Deng, Darcy E. Wagner, David M. Hoganson, Daniel J. Weiss, Joseph Platz, Takamaru Ashikaga, Zain Khalpey, Zachary D. Borg, Elice M. Brooks, Charles S. Parsons, Ying-Wai Lam, Nicholas R. Bonenfant, Michael J. DeSarno, Dino Sokocevic, Rachael A. Oldinski
Publikováno v:
Biomaterials. 35:2664-2679
Acellular scaffolds from complex whole organs such as lung are being increasingly studied for ex vivo organ generation and for in vitro studies of cell-extracellular matrix interactions. We have established effective methods for efficient de and rece
Autor:
Bin Deng, Amanda B. Daly, Takamaru Ashikaga, Zachary D. Borg, Daniel J. Weiss, Melissa J. Lathrop, Darcy E. Wagner, Charles S. Parsons, Nicholas R. Bonenfant, John D. Wallis, Michael J. DeSarno, Elice M. Brooks, Roberto Loi, Dino Sokocevic, Ying-Wai Lam
Publikováno v:
Biomaterials. 35:3281-3297
Acellular whole human lung scaffolds represent a unique opportunity for ex vivo tissue engineering. However, it remains unclear whether lungs from individuals with chronic lung diseases such as chronic obstructive pulmonary disease (COPD) can be appr
Publikováno v:
Gastroenterology. 139:249-258
In adults, irritable bowel syndrome (IBS) and functional dyspepsia (FD) are chronic conditions that often start during childhood. We investigated mucosal serotonin (5-HT) signaling in children with the idea that data from subjects with a shorter hist
Autor:
Peter L. Moses, Lisa M. Glass, Neil Hyman, Meagan Costedio, Elice M. Brooks, Hagen Blaszyk, Matthew Coates, Gary M. Mawe, Michael J. Wood, Doris B. Strader, Allison L Ciolino, Eric K. Ganguly
Publikováno v:
American Journal of Gastroenterology. 105:1173-1180
Changes in mucosal serotonin (5-HT) signaling have been detected in a number of functional and inflammatory disorders of the gastrointestinal (GI) tract. This study was undertaken to determine whether chronic constipation (CC) is associated with diso
Autor:
Janice A. Nicklas, Shelly Naud, J. Patrick O'Neill, Cheryl Powden, Elice M. Brooks, Richard F. Branda
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 615:12-17
Folic acid deficiency (FA-) augments DNA damage caused by alkylating agents. The role of DNA repair in modulating this damage was investigated in mice. Weanling wild-type or 3-methyladenine glycosylase (Aag) null mice were maintained on a FA- diet or
Autor:
Elice M. Brooks, Nicholas R. Bonenfant, Fernanda F. Cruz, Elizabeth K. Sage, Dino Sokocevic, Sam M. Janes, Sherrill L. Macura, Maximilian B. MacPherson, Arti Shukla, Daniel J. Weiss, Melissa J. Lathrop, Chad Steele, Brooke T. Mossman, Chad W. Dunaway, Stacie L. Beuschel
Publikováno v:
Cancer gene therapy. 22(1)
Malignant mesothelioma (MM) remains a highly deadly malignancy with poor treatment option. The MM cells further promote a highly inflammatory microenvironment, which contributes to tumor initiation, development, severity and propagation. We reasoned
Autor:
Dino Sokocevic, Fernanda F. Cruz, Chad W. Dunaway, Melissa J. Lathrop, Roberto Loi, Daniel J. Weiss, Elice M. Brooks, Chad Steele, Meagan Goodwin, Nick R. Bonenfant, Zachary D. Borg
Publikováno v:
Stem cells translational medicine. 3(2)
Systemic administration of mesenchymal stromal cells (MSCs) suppresses airway inflammation and methacholine-induced airway hyper-responsiveness (AHR) in mouse models of T helper cell (Th) type 2-mediated eosinophilic allergic airway inflammation (AAI
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 473:51-71
Folic acid deficiency acts synergistically with alkylating agents to increase genetic damage at the HPRT locus in Chinese hamster ovary cells in vitro and in rat splenocytes in vivo. The present studies extend these observations to human cells and, i
Publikováno v:
Clinical Chemistry. 38:507-511
We investigated the prevalence and characteristics of intestinal alkaline phosphatase (ALP; EC 3.1.3.1) identified in human serum by cellulose acetate electrophoresis in 8% of fasting serum samples from hospital patients (n = 500) and in 35% of fasti
Publikováno v:
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 21(5)
Selective serotonin-reuptake inhibitors are therapies for psychological and bowel disorders, but produce adverse effects in the non-targeted system. To determine whether human serotonin-selective reuptake transporter (SERT) transcripts in the intesti