Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Elias T. Gaillard"'
Autor:
Susan D. Hester, Elias T. Gaillard, Tanya Moore, Michael H. George, Charles E. Wood, William O. Ward, Carlin Okerberg, Anthony B. DeAngelo, Anna Fisher, Brian N. Chorley, April D. Lake, Hongzu Ren, Gleta Carswell, Beena Vallanat
Publikováno v:
Carcinogenesis. 36:782-791
Environmental exposures occurring early in life may have an important influence on cancer risk later in life. Here, we investigated carryover effects of dichloroacetic acid (DCA), a small molecule analog of pyruvate with metabolic programming propert
Autor:
Supriya Jayadev, Qihong Huang, Kerry T. Blanchard, Franklin D. Pack, Elias T. Gaillard, James H. Stoltz, Brian Knight, Xidong Jin
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 549:147-167
Microarray technology continues to gain increased acceptance in the drug development process, particularly at the stage of toxicology and safety assessment. In the current study, microarrays were used to investigate gene expression changes associated
Autor:
Jeff W. Chou, Elias T. Gaillard, Raymond E. Stoll, Kerry T. Blanchard, Pierre R. Bushel, Hisham K. Hamadeh, Charles J. Tucker, Qihong Huang, Jennifer B. Collins, Robert R. Maronpot, Supriya Jayadev, Cynthia A. Afshari
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 549:169-183
Molecular techniques, such as cDNA microarrays, are being used to aid in the elucidation of the mechanisms of toxicity of a variety of compounds. In this study, we evaluate the molecular effects of furan in the rat liver. Sprague-Dawley rats were exp
Publikováno v:
Journal of Investigative Surgery. 15:81-89
In the development of novel pharmaceutical compounds, pharmacokinetic parameters, such as the extent of biliary excretion, must be characterized. Pharmacokinetic studies in nonrodent species, typically dogs, are generally required for new drug approv
Autor:
Lynn Pantages, George Kukolj, Brian Knight, Mireille Cartier, Louiza Mahrouche, Martine Brault, Tim T. Chiu, Louise Pilote, Peter W. White, Michael G. Cordingley, Nathalie Uyttersprot, Frédéric H. Vaillancourt, Richard Bethell, Anne-Marie Faucher, James H. Stoltz, Steffen Breitfelder, Elias T. Gaillard, Mary McFarland, Huiping Jiang
Publikováno v:
Journal of Virology
Phosphatidylinositol-4-kinase IIIα (PI4KIIIα) is an essential host cell factor for hepatitis C virus (HCV) replication. An N-terminally truncated 130-kDa form was used to reconstitute an in vitro biochemical lipid kinase assay that was optimized fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb796c8b8a6dc63ee044eee1c9692ef5
https://europepmc.org/articles/PMC3486294/
https://europepmc.org/articles/PMC3486294/
Autor:
Michael H. George, Gregory S. Travlos, Anthony B. DeAngelo, Elias T. Gaillard, Douglas C. Wolf, Michelle J. Hooth, Gary A. Boorman
Publikováno v:
Toxicologic pathology. 29(2)
Chlorine dioxide (ClO 2) is an effective drinking water disinfectant, but sodium chlorate (NaClO3) has been identified as a potentially harmful disinfection by-product. Studies were performed to describe the development of thyroid lesions in animals
Autor:
Elias T Gaillard, Charles B Clifford
Publisher Summary Many pathogens have been reported to cause disease in the laboratory rat. This chapter concentrates on the pathology of the more common pathogens of the laboratory rat. Based on serologic surveys, parvo viruses are some of the most
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21f7e9644fd70828d8f784fbf3860abc
https://doi.org/10.1016/b978-012426400-7.50046-7
https://doi.org/10.1016/b978-012426400-7.50046-7
Publikováno v:
Clinicalexperimental metastasis. 6(1)
The lung colonizing potential of 6 xenografted human colorectal adenocarcinomas following tail vein inoculation of tumor cell suspensions into gnotobiotic 3-4-week-old congenitally athymic mice was investigated. One of the lines, CRCo2, was of partic