Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Elias R. Gerrick"'
Autor:
Elias R. Gerrick, Leila B. DeSchepper, Claire M. Mechler, Lydia-Marie Joubert, Freeland Dunker, Timothy J. Colston, Michael R. Howitt
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
ABSTRACTThe eukaryome of mammals contains parabasalid protists that dramatically affect host immune function and health. However, the prevalence and diversity of parabasalids in wild reptiles and the consequences of captivity on these symbiotic proti
Externí odkaz:
https://doaj.org/article/2ce0771662e842ff93714e3f3e9475c2
Autor:
Michael A. DeJesus, Elias R. Gerrick, Weizhen Xu, Sae Woong Park, Jarukit E. Long, Cara C. Boutte, Eric J. Rubin, Dirk Schnappinger, Sabine Ehrt, Sarah M. Fortune, Christopher M. Sassetti, Thomas R. Ioerger
Publikováno v:
mBio, Vol 8, Iss 1 (2017)
ABSTRACT For decades, identifying the regions of a bacterial chromosome that are necessary for viability has relied on mapping integration sites in libraries of random transposon mutants to find loci that are unable to sustain insertion. To date, the
Externí odkaz:
https://doaj.org/article/a77bd7f0cb4b428b9bb78ab3fcebcc71
Autor:
Elias R Gerrick, Leila B DeSchepper, Claire M Mechler, Lydia-Marie Joubert, Freeland Dunker, Timothy J Colston, Michael R Howitt
Publikováno v:
bioRxiv
Parabasalid protists recently emerged as keystone members of the mammalian microbiota with important effects on their host's health. However, the prevalence and diversity of parabasalids in wild reptiles and the consequences of captivity and other en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bc002087a1386b6963e0e376b18e6c4
https://europepmc.org/articles/PMC10245904/
https://europepmc.org/articles/PMC10245904/
Autor:
Kimberline Y Gerrick, Elias R Gerrick, Anuj Gupta, Sarah J Wheelan, Srinivasan Yegnasubramanian, Elizabeth M Jaffee
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0208602 (2018)
Macrophages are key inflammatory immune cells that display dynamic phenotypes and functions in response to their local microenvironment. Major advances have occurred in understanding the transcriptional, epigenetic, and functional differences in vari
Externí odkaz:
https://doaj.org/article/9fa4135bf2d9403484c5728d477ff71c
Autor:
Connie Fung, Lisa M. Fraser, Gabriel M. Barrón, Matthew B. Gologorsky, Samantha N. Atkinson, Elias R. Gerrick, Michael Hayward, Jennifer Ziegelbauer, Jessica A. Li, Katherine F. Nico, Miles D.W. Tyner, Leila B. DeSchepper, Amy Pan, Nita H. Salzman, Michael R. Howitt
Succinate produced by the commensal protistTritrichomonas musculis(T. mu) stimulates chemosensory tuft cells, resulting in intestinal type 2 immunity. Tuft cells express the succinate receptor SUCNR1, yet this receptor does not mediate anti-helminth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f41a3cf4809fc819e4d611fc69229773
https://doi.org/10.1101/2022.10.24.512770
https://doi.org/10.1101/2022.10.24.512770
Autor:
Elias R. Gerrick, Soumaya Zlitni, Patrick T. West, Claire M. Mechler, Jessica A. Li, Steven K. Higginbottom, Christopher J. Severyn, Frauke Kracke, Alfred M. Spormann, Justin L. Sonnenburg, Ami S. Bhatt, Michael R. Howitt
SummaryProtists in the gut microbiota influence intestinal immunity and epithelial composition, yet the mechanisms used by these protists to shape the gut environment remain poorly understood. Here, we identify a new protist species, Tritrichomonas c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6181c78d1e3bdbd65342cafd3e3bfbbe
https://doi.org/10.1101/2022.08.26.505490
https://doi.org/10.1101/2022.08.26.505490
Autor:
Michael R. Chase, Rushdy Ahmad, Vincent H Lin, Thibault Barbier, Jonathan Livny, Matthew J. Szucs, Brian Tjaden, Sarah M. Fortune, Raylin Xu, Jeremy M. Rock, Josie François, Elias R. Gerrick
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance This work describes the most extensive discovery and functional characterization of small regulatory RNAs (sRNAs) in Mycobacterium tuberculosis to date. We comprehensively define the sRNAs expressed in M. tuberculosis under five host-lik
Autor:
Frank L. Acosta, S. Samuel Bederman, Ronald Sahyouni, Yu-Po Lee, Saif Aldeen Farhan, Elias R. Gerrick, Nitin N. Bhatia, Arif Pendi
Publikováno v:
Journal of spine surgery (Hong Kong). 4(2)
Background: Supplemental intrathecal morphine (ITM) represents an option to manage postoperative pain after spine surgery due to ease of administration and ability to confer effective short-term analgesia at low dosages. However, whether ITM increase
Autor:
Ulla F. Lang, Mireia Coscolla, Richa Gawande, Sarah M. Fortune, Michael R. Chase, Sebastien Gagneux, Christopher B. Ford, Jeremy M. Rock, Elias R. Gerrick, Meindert H. Lamers
Publikováno v:
Nature genetics
The DNA replication machinery is an important target for antibiotic development in increasingly drug-resistant bacteria, including Mycobacterium tuberculosis. Although blocking DNA replication leads to cell death, disrupting the processes used to ens
Autor:
Dirk Schnappinger, Eric J. Rubin, Thomas R. Ioerger, Sae Woong Park, Elias R. Gerrick, Jarukit E. Long, Sarah M. Fortune, Cara C. Boutte, Christopher M. Sassetti, Sabine Ehrt, Michael A. DeJesus, Weizhen Xu
Publikováno v:
mBio, Vol 8, Iss 1 (2017)
mBio
mBio, Vol 8, Iss 1, p e02133-16 (2017)
mBio
mBio, Vol 8, Iss 1, p e02133-16 (2017)
For decades, identifying the regions of a bacterial chromosome that are necessary for viability has relied on mapping integration sites in libraries of random transposon mutants to find loci that are unable to sustain insertion. To date, these studie