Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Elias Leiva-Salcedo"'
Publikováno v:
Molecular Brain, Vol 17, Iss 1, Pp 1-4 (2024)
Abstract TRPM4 is a non-selective cation channel activated by intracellular Ca2+ but only permeable to monovalent cations, its activation regulates membrane potential and intracellular calcium. This channel participates in the migration and adhesion
Externí odkaz:
https://doaj.org/article/3f2c6afdef1e48a6999d4bdc957a0b60
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
TRPM4 is a calcium activated non-selective cation channel, impermeable to Ca2+, in neurons it has been implicated in the regulation of the excitability and in the persistent firing. Cholinergic stimulation is also implicated in changes in excitabilit
Externí odkaz:
https://doaj.org/article/b97ebc942cb74cf08aa2d9eebde9c12d
Autor:
Alejandro Escobar, Felipe E. Reyes-López, Mónica L. Acevedo, Luis Alonso-Palomares, Fernando Valiente-Echeverría, Ricardo Soto-Rifo, Hugo Portillo, Jimena Gatica, Ivan Flores, Estefanía Nova-Lamperti, Carlos Barrera-Avalos, María Rosa Bono, Leonardo Vargas, Valeska Simon, Elias Leiva-Salcedo, Cecilia Vial, Juan Hormazabal, Lina Jimena Cortes, Daniel Valdés, Ana M. Sandino, Mónica Imarai, Claudio Acuña-Castillo
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
CoronaVac vaccine from Sinovac Life Science is currently being used in several countries. In Chile, the effectiveness of preventing hospitalization is higher than 80% with a vaccination schedule. However, to date, there are no data about immune respo
Externí odkaz:
https://doaj.org/article/567bda70ec194d8aa689dad8556c9e4f
Publikováno v:
Frontiers in Neuroanatomy, Vol 15 (2021)
TRPM4 is a non-selective cation channel activated by intracellular calcium and permeable to monovalent cations. This channel participates in the control of neuronal firing, neuronal plasticity, and neuronal death. TRPM4 depolarizes dendritic spines a
Externí odkaz:
https://doaj.org/article/133702131508400a9ab5f52bcbd09004
Autor:
Denise Riquelme, Francisco A. Peralta, Franco D. Navarro, Claudio Moreno, Elias Leiva-Salcedo
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 10, p 5268 (2021)
Pyramidal neurons in the medial prefrontal cortical layer 2/3 are an essential contributor to the cellular basis of working memory; thus, changes in their intrinsic excitability critically affect medial prefrontal cortex (mPFC) functional properties.
Externí odkaz:
https://doaj.org/article/0400d11f31944b298f589da6a83f9fcf
Autor:
Denise Riquelme, Ian Silva, Ashleigh M. Philp, Juan P. Huidobro-Toro, Oscar Cerda, James S. Trimmer, Elias Leiva-Salcedo
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
TRPM4 is a Ca2+-activated non-selective cationic channel that conducts monovalent cations. TRPM4 has been proposed to contribute to burst firing and sustained activity in several brain regions, however, the cellular and subcellular pattern of TRPM4 e
Externí odkaz:
https://doaj.org/article/91fb8267fd3849118bbe1e529cde222b
Autor:
Jonathan Morales, Carlos Barrera-Avalos, Carlos Castro, Stephanie Castillo, Claudio Barrientos, Claudia Robles-Planells, Ximena López, Ernesto Torres, Margarita Montoya, Marcelo Cortez-San Martín, Denise Riquelme, Alejandro Escobar, Ricardo Fernández, Mónica Imarai, Daniela Sauma, Leonel E. Rojo, Elias Leiva-Salcedo, Claudio Acuña-Castillo
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Antigen cross-presentation is a crucial step in the assembly of an antitumor immune response leading to activation of naïve CD8 T cells. This process has been extensively used in clinical trials, in which dendritic cells generated in vitro are loade
Externí odkaz:
https://doaj.org/article/51ff5d8be73c4a808e35262395de0beb
Autor:
Milos B. Rokic, Patricio Castro, Elias Leiva-Salcedo, Melanija Tomic, Stanko S. Stojilkovic, Claudio Coddou
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 4, p 1161 (2018)
P2X2 receptors (P2X2R) exhibit a slow desensitization during the initial ATP application and a progressive, calcium-dependent increase in rates of desensitization during repetitive stimulation. This pattern is observed in whole-cell recordings from c
Externí odkaz:
https://doaj.org/article/09389b232e4344eb843140547e30e44b
Publikováno v:
Biological Research, Vol 35, Iss 2, Pp 287-294 (2002)
Serum levels of T-kininogen increase dramatically as rats approach the end of their lifespan. Stable expression of the protein in Balb/c 3T3 fibroblasts leads to a dramatic inhibition of cell proliferation, as well as inhibition of the ERK signaling
Externí odkaz:
https://doaj.org/article/aa0949ea6ed845c5aba93bd838affef5
Autor:
Elias Leiva-Salcedo, Claudio Coddou, Felipe E. Rodríguez, Antonello Penna, Ximena Lopez, Tanya Neira, Ricardo Fernández, Mónica Imarai, Miguel Rios, Jorge Escobar, Margarita Montoya, J. Pablo Huidobro-Toro, Alejandro Escobar, Claudio Acuña-Castillo
Publikováno v:
Mediators of Inflammation, Vol 2011 (2011)
The purinergic P2X7 receptor (P2X7R) plays an important role during the immune response, participating in several events such as cytokine release, apoptosis, and necrosis. The bacterial endotoxin lipopolysaccharide (LPS) is one of the strongest stimu
Externí odkaz:
https://doaj.org/article/70ed529568aa4b4d9626a6b70ddc95c5