Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Elias Iturrospe"'
Autor:
Rani Robeyns, Angela Sisto, Elias Iturrospe, Katyeny Manuela da Silva, Maria van de Lavoir, Vincent Timmerman, Adrian Covaci, Sigrid Stroobants, Alexander L. N. van Nuijs
Publikováno v:
Metabolites, Vol 14, Iss 5, p 248 (2024)
Torin1, a selective kinase inhibitor targeting the mammalian target of rapamycin (mTOR), remains widely used in autophagy research due to its potent autophagy-inducing abilities, regardless of its unspecific properties. Recognizing the impact of mTOR
Externí odkaz:
https://doaj.org/article/739793a46fab4b7c926ef1fe9f523065
Publikováno v:
BMC Health Services Research, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background A longstanding debate exists about including a ‘reason for use’ on prescriptions for medication. Little is known, however, about patients’ opinions on this subject. Methods An internet-based questionnaire, consisting mainly
Externí odkaz:
https://doaj.org/article/ca5ecc0508fa497cb28ec0d7fcbe9f76
Autor:
Katyeny Manuela da Silva, Elias Iturrospe, Chloe Bars, Dries Knapen, Steven Van Cruchten, Adrian Covaci, Alexander L. N. van Nuijs
Publikováno v:
Metabolites, Vol 11, Iss 9, p 635 (2021)
Metabolomics has achieved great progress over the last 20 years, and it is currently considered a mature research field. As a result, the number of applications in toxicology, biomarker, and drug discovery has also increased. Toxicometabolomics has e
Externí odkaz:
https://doaj.org/article/e1208cc4edb948aa8980abb96d76fc69
Chlorogenic Acid as a Model Compound for Optimization of an In Vitro Gut Microbiome-Metabolism Model
Autor:
Olivier Mortelé, Elias Iturrospe, Annelies Breynaert, Christine Lammens, Xavier Basil Britto, Surbhi Malhotra-Kumar, Philippe Jorens, Luc Pieters, Alexander L. N. van Nuijs, Nina Hermans
Publikováno v:
Proceedings, Vol 11, Iss 1, p 31 (2019)
It has been believed that the metabolism of xenobiotics occurred mainly by the cytochrome P450 enzyme system in the liver. However, recent data clearly suggest a significant role for the gut microbiota in the metabolism of xenobiotic compounds. This
Externí odkaz:
https://doaj.org/article/b5dd254c9fcb4c05bc397f56cae48688
Autor:
Elias Iturrospe, Rani Robeyns, Katyeny Manuela da Silva, Maria van de Lavoir, Joost Boeckmans, Tamara Vanhaecke, Alexander L. N. van Nuijs, Adrian Covaci
Publikováno v:
Archives of toxicology
Despite the high prevalence of alcoholic liver disease, its identification and characterization remain poor, especially in early stages such as alcoholic fatty liver disease and alcoholic steatohepatitis. This latter implies diagnostic difficulties,
Autor:
Katyeny Manuela da Silva, Elias Iturrospe, Rik van den Boom, Maria van de Lavoir, Rani Robeyns, Lucia Vergauwen, Dries Knapen, Matthias Cuykx, Adrian Covaci, Alexander L. N. van Nuijs
Publikováno v:
Journal of separation science
Lipidomics analysis of zebrafish tissues has shown promising results to understand disease-related outcomes of exposure to toxic substances at molecular level. However, knowledge about their lipidome is limited, as most untargeted studies only identi
Autor:
Giulia Poma, Matthias Cuykx, Katyeny Manuela Da Silva, Elias Iturrospe, Alexander L.N. van Nuijs, Arnold van Huis, Adrian Covaci
Publikováno v:
Trends in Food Science and Technology 119 (2022)
Trends in Food Science and Technology, 119, 371-377
Trends in food science and technology
Trends in Food Science and Technology, 119, 371-377
Trends in food science and technology
Background Edible insects are a nutritious and sustainable alternative source of animal proteins, and consequently are nowadays promoted as human food and animal feed worldwide. Ensuring the quality, safety, and traceability of insect foods is thus c
Autor:
Elias, Iturrospe, Katyeny Manuela, da Silva, Maria, van de Lavoir, Rani, Robeyns, Matthias, Cuykx, Tamara, Vanhaecke, Alexander L N, van Nuijs, Adrian, Covaci
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2571
Metabolites represent the most downstream level of the cellular organization. Hence, an in vitro untargeted metabolomics approach is extremely valuable to deepen the understanding of how endogenous metabolites in cells are altered under a given biolo
Autor:
Katyeny Manuela Da Silva, Alexander Van Nuijs, Elias Iturrospe, Tamara Vanhaecke, Joost Boeckmans, Rani Robeyns, Adrian Covaci, Maria Van de Lavoir
Publikováno v:
Journal of proteome research
Alcoholic liver disease is highly prevalent but poorly identified and characterized, leading to knowledge gaps, which impairs early diagnosis. Excessive alcohol consumption is known to alter lipid metabolism, followed by progressive intracellular lip
Autor:
Yunsun Jeong, Katyeny Manuela Da Silva, Elias Iturrospe, Yukiko Fuiji, Tim Boogaerts, Alexander L.N. van Nuijs, Jeremy Koelmel, Adrian Covaci
Publikováno v:
Journal of hazardous materials
With the growing concern regarding the health risks of per- and polyfluoroalkyl substances (PFAS), there is an increasing demand for the identification of emerging PFAS. This study provides a comprehensive investigation of legacy and emerging PFAS in