Lateralized Subthalamic Stimulation for Axial Dysfunction in Parkinson's Disease: Exploratory Outcomes and Open-Label Extension.

Autor: Lizarraga KJ; The Edmond J. Safra Program in Parkinson's Disease and the Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, University Hospital Network and Division of Neurology, Department of Medicine, University of Toronto, Toronto, ON, Canada.; Motor Physiology and Neuromodulation Program, Division of Movement Disorders, Department of Neurology, University of Rochester, Rochester, NY, USA., Gnanamanogaran B; The Edmond J. Safra Program in Parkinson's Disease and the Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, University Hospital Network and Division of Neurology, Department of Medicine, University of Toronto, Toronto, ON, Canada.; University of Toronto, Toronto, ON, Canada., Al-Ozzi TM; University of Toronto, Toronto, ON, Canada.; Krembil Research Institute, Toronto, ON, Canada.; Departments of Surgery and Physiology, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada.; Graduate Training Center of Neuroscience, Universitätsklinikum Tübingen, Tübingen, Germany., Cohn M; Krembil Research Institute, Toronto, ON, Canada.; Department of Psychology, University of Toronto, Toronto, ON, Canada., Tomlinson G; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada.; University Health Network, Toronto, ON, Canada., Boutet A; Department of Psychology, University of Toronto, Toronto, ON, Canada.; Joint Department of Medical Imaging, University of Toronto, Toronto, ON, Canada.; Division of Neurosurgery, Department of Surgery, University Health Network and University of Toronto, Toronto, ON, Canada., Elias GJB; University Health Network, Toronto, ON, Canada.; Division of Neurosurgery, Department of Surgery, University Health Network and University of Toronto, Toronto, ON, Canada., Germann J; University Health Network, Toronto, ON, Canada.; Division of Neurosurgery, Department of Surgery, University Health Network and University of Toronto, Toronto, ON, Canada., Soh D; The Edmond J. Safra Program in Parkinson's Disease and the Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, University Hospital Network and Division of Neurology, Department of Medicine, University of Toronto, Toronto, ON, Canada.; Alfred Hospital, Melbourne, VIC, Australia., Kalia SK; Krembil Research Institute, Toronto, ON, Canada.; Division of Neurosurgery, Department of Surgery, University Health Network and University of Toronto, Toronto, ON, Canada.; CenteR for Advancing Neurotechnological Innovation to Application (CRANIA), Toronto, ON, Canada., Hodaie M; Krembil Research Institute, Toronto, ON, Canada.; Division of Neurosurgery, Department of Surgery, University Health Network and University of Toronto, Toronto, ON, Canada., Munhoz RP; The Edmond J. Safra Program in Parkinson's Disease and the Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, University Hospital Network and Division of Neurology, Department of Medicine, University of Toronto, Toronto, ON, Canada.; Krembil Research Institute, Toronto, ON, Canada., Marras C; The Edmond J. Safra Program in Parkinson's Disease and the Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, University Hospital Network and Division of Neurology, Department of Medicine, University of Toronto, Toronto, ON, Canada.; Krembil Research Institute, Toronto, ON, Canada., Hutchison WD; Krembil Research Institute, Toronto, ON, Canada.; Departments of Surgery and Physiology, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada.; Division of Neurosurgery, Department of Surgery, University Health Network and University of Toronto, Toronto, ON, Canada.; CenteR for Advancing Neurotechnological Innovation to Application (CRANIA), Toronto, ON, Canada., Lozano AM; Krembil Research Institute, Toronto, ON, Canada.; Division of Neurosurgery, Department of Surgery, University Health Network and University of Toronto, Toronto, ON, Canada., Lang AE; The Edmond J. Safra Program in Parkinson's Disease and the Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, University Hospital Network and Division of Neurology, Department of Medicine, University of Toronto, Toronto, ON, Canada.; Krembil Research Institute, Toronto, ON, Canada., Fasano A; The Edmond J. Safra Program in Parkinson's Disease and the Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, University Hospital Network and Division of Neurology, Department of Medicine, University of Toronto, Toronto, ON, Canada.; Krembil Research Institute, Toronto, ON, Canada.; CenteR for Advancing Neurotechnological Innovation to Application (CRANIA), Toronto, ON, Canada.

Publikováno v: Movement disorders clinical practice [Mov Disord Clin Pract] 2024 Nov; Vol. 11 (11), pp. 1421-1426. Date of Electronic Publication: 2024 Aug 13.

Comparative neural correlates of DBS and MRgFUS lesioning for tremor control in essential tremor.

Autor: Germann J; Division of Neurosurgery, University of Toronto, Toronto, Ontario, Canada.; Krembil Brain Institute, Toronto, Ontario, Canada.; Center for Advancing Neurotechnological Innovation to Application (CRANIA), Toronto, Ontario, Canada., Santyr B; Division of Neurosurgery, University of Toronto, Toronto, Ontario, Canada., Boutet A; Joint Department of Medical Imaging, Toronto Western Hospital, Toronto, Ontario, Canada., Sarica C; Division of Neurosurgery, University of Toronto, Toronto, Ontario, Canada., Chow CT; Division of Neurosurgery, University of Toronto, Toronto, Ontario, Canada., Elias GJB; Division of Neurosurgery, University of Toronto, Toronto, Ontario, Canada., Vetkas A; Division of Neurosurgery, University of Toronto, Toronto, Ontario, Canada., Yang A; Division of Neurosurgery, University of Toronto, Toronto, Ontario, Canada., Hodaie M; Division of Neurosurgery, University of Toronto, Toronto, Ontario, Canada.; Krembil Brain Institute, Toronto, Ontario, Canada., Fasano A; Krembil Brain Institute, Toronto, Ontario, Canada.; Edmond J. Safra Program in Parkinson's Disease, Morton and Gloria Shulman Movement Disorders Clinic, Toronto WesternHospital, Toronto, Ontario, Canada.; Division of Neurology, University of Toronto, Toronto, Ontario, Canada., Kalia SK; Division of Neurosurgery, University of Toronto, Toronto, Ontario, Canada.; Krembil Brain Institute, Toronto, Ontario, Canada., Schwartz ML; Division of Neurosurgery, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada., Lozano AM; Division of Neurosurgery, University of Toronto, Toronto, Ontario, Canada andres.lozano@uhnresearch.ca.; Krembil Brain Institute, Toronto, Ontario, Canada.

Publikováno v: Journal of neurology, neurosurgery, and psychiatry [J Neurol Neurosurg Psychiatry] 2024 Jan 11; Vol. 95 (2), pp. 180-183. Date of Electronic Publication: 2024 Jan 11.

WarpDrive: Improving spatial normalization using manual refinements.

Autor: Oxenford S; Movement Disorders and Neuromodulation Unit, Department of Neurology, Charité -Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany. Electronic address: simon.oxenford@charite.de., Ríos AS; Movement Disorders and Neuromodulation Unit, Department of Neurology, Charité -Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Hollunder B; Movement Disorders and Neuromodulation Unit, Department of Neurology, Charité -Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany; Einstein Center for Neurosciences Berlin, Charité - Universitätsmedizin Berlin, Berlin, Germany; Berlin School of Mind and Brain, Humboldt-Universität zu Berlin, Berlin, Germany., Neudorfer C; Movement Disorders and Neuromodulation Unit, Department of Neurology, Charité -Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany; Brain Modulation Lab, Department of Neurosurgery, Massachusetts General Hospital, Boston, MA 02114, United States; Center for Brain Circuit Therapeutics Department of Neurology Brigham & Women's Hospital, Harvard Medical School, Boston, MA, United States., Boutet A; Division of Neurosurgery, Department of Surgery, University Health Network and University of Toronto, Toronto, ON M5T2S8, Canada; Krembil Research Institute, University of Toronto, Toronto, ON M5T2S8, Canada; Joint Department of Medical Imaging, University of Toronto, Toronto, ON M5T1W7, Canada., Elias GJB; Division of Neurosurgery, Department of Surgery, University Health Network and University of Toronto, Toronto, ON M5T2S8, Canada; Krembil Research Institute, University of Toronto, Toronto, ON M5T2S8, Canada., Germann J; Division of Neurosurgery, Department of Surgery, University Health Network and University of Toronto, Toronto, ON M5T2S8, Canada; Krembil Research Institute, University of Toronto, Toronto, ON M5T2S8, Canada., Loh A; Division of Neurosurgery, Department of Surgery, University Health Network and University of Toronto, Toronto, ON M5T2S8, Canada; Krembil Research Institute, University of Toronto, Toronto, ON M5T2S8, Canada., Deeb W; UMass Chan Medical School, Department of Neurology, Worcester, MA 01655, United States; UMass Memorial Health, Department of Neurology, Worcester, MA 01655, United States., Salvato B; University of Florida Health Jacksonville, Jacksonville, FL, United States., Almeida L; Department of Neurology, University of Minnesota, Twin Cities Campus, Minneapolis, MN, United States., Foote KD; Norman Fixel Institute for Neurological Diseases, Departments of Neurology and Neurosurgery, University of Florida, Gainesville, FL, United States., Amaral R; Cerebral Imaging Centre, Douglas Research Centre, Montreal, QC, Canada., Rosenberg PB; Department of Psychiatry and Behavioral Sciences and Richman Family Precision Medicine Center of Excellence, School of Medicine, Johns Hopkins University, Baltimore, MD, United States., Tang-Wai DF; Krembil Research Institute, University of Toronto, Toronto, ON M5T2S8, Canada; Department of Medicine, Division of Neurology, University Health Network and University of Toronto, Toronto, ON M5T2S8, Canada., Wolk DA; Department of Neurology, University of Pennsylvania, Philadelphia, PA, United States., Burke AD; Barrow Neurological Institute, Phoenix, AZ, United States., Sabbagh MN; Barrow Neurological Institute, Phoenix, AZ, United States., Salloway S; Department of Psychiatry and Human Behavior and Neurology, Alpert Medical School of Brown University, Providence, RI, United States; Memory & Aging Program, Butler Hospital, Providence, United States., Chakravarty MM; Cerebral Imaging Centre, Douglas Research Centre, Montreal, QC, Canada; Department of Psychiatry, McGill University, Montreal, QC, Canada; Biological and Biomedical Engineering, McGill University, Montreal, QC, Canada., Smith GS; Cerebral Imaging Centre, Douglas Research Centre, Montreal, QC, Canada., Lyketsos CG; Cerebral Imaging Centre, Douglas Research Centre, Montreal, QC, Canada., Okun MS; Norman Fixel Institute for Neurological Diseases, Departments of Neurology and Neurosurgery, University of Florida, Gainesville, FL, United States., Anderson WS; Johns Hopkins School of Medicine, Baltimore, MD, United States., Mari Z; Johns Hopkins School of Medicine, Baltimore, MD, United States; Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV, United States., Ponce FA; Barrow Neurological Institute, Phoenix, AZ, United States., Lozano A; Division of Neurosurgery, Department of Surgery, University Health Network and University of Toronto, Toronto, ON M5T2S8, Canada; Krembil Research Institute, University of Toronto, Toronto, ON M5T2S8, Canada., Neumann WJ; Movement Disorders and Neuromodulation Unit, Department of Neurology, Charité -Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Al-Fatly B; Movement Disorders and Neuromodulation Unit, Department of Neurology, Charité -Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Horn A; Movement Disorders and Neuromodulation Unit, Department of Neurology, Charité -Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany; Brain Modulation Lab, Department of Neurosurgery, Massachusetts General Hospital, Boston, MA 02114, United States; Center for Brain Circuit Therapeutics Department of Neurology Brigham & Women's Hospital, Harvard Medical School, Boston, MA, United States.

Publikováno v: Medical image analysis [Med Image Anal] 2024 Jan; Vol. 91, pp. 103041. Date of Electronic Publication: 2023 Nov 19.

Dissociable default-mode subnetworks subserve childhood attention and cognitive flexibility: Evidence from deep learning and stereotactic electroencephalography.

Autor: Warsi NM; Division of Neurosurgery, The Hospital for Sick Children, 555 University Ave., Toronto, Ontario, Canada; Department of Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada., Wong SM; Department of Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada; Program in Neuroscience and Mental Health, Hospital for Sick Children, Toronto, Ontario, Canada., Germann J; Division of Neurosurgery, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada., Boutet A; Division of Neurosurgery, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada; Joint Department of Medical Imaging, University of Toronto, Toronto, Ontario, Canada., Arski ON; Program in Neuroscience and Mental Health, Hospital for Sick Children, Toronto, Ontario, Canada., Anderson R; Maerospace Corporation, Waterloo, Ontario, Canada., Erdman L; Vector Institute for Artificial Intelligence, University Health Network, Toronto, Ontario, Canada., Yan H; Division of Neurosurgery, The Hospital for Sick Children, 555 University Ave., Toronto, Ontario, Canada., Suresh H; Division of Neurosurgery, The Hospital for Sick Children, 555 University Ave., Toronto, Ontario, Canada; Department of Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada., Gouveia FV; Program in Neuroscience and Mental Health, Hospital for Sick Children, Toronto, Ontario, Canada., Loh A; Division of Neurosurgery, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada; Joint Department of Medical Imaging, University of Toronto, Toronto, Ontario, Canada., Elias GJB; Division of Neurosurgery, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada; Joint Department of Medical Imaging, University of Toronto, Toronto, Ontario, Canada., Kerr E; Department of Psychology, The Hospital for Sick Children, University of Toronto, 555 University Ave., Toronto, Ontario, Canada, M5G 1X8., Smith ML; Department of Psychology, The Hospital for Sick Children, University of Toronto, 555 University Ave., Toronto, Ontario, Canada, M5G 1X8., Ochi A; Division of Neurosurgery, The Hospital for Sick Children, 555 University Ave., Toronto, Ontario, Canada., Otsubo H; Division of Neurosurgery, The Hospital for Sick Children, 555 University Ave., Toronto, Ontario, Canada., Sharma R; Division of Neurosurgery, The Hospital for Sick Children, 555 University Ave., Toronto, Ontario, Canada., Jain P; Division of Neurosurgery, The Hospital for Sick Children, 555 University Ave., Toronto, Ontario, Canada., Donner E; Division of Neurosurgery, The Hospital for Sick Children, 555 University Ave., Toronto, Ontario, Canada., Lozano AM; Division of Neurosurgery, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada., Snead OC; Division of Neurosurgery, The Hospital for Sick Children, 555 University Ave., Toronto, Ontario, Canada., Ibrahim GM; Division of Neurosurgery, The Hospital for Sick Children, 555 University Ave., Toronto, Ontario, Canada; Department of Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada; Program in Neuroscience and Mental Health, Hospital for Sick Children, Toronto, Ontario, Canada. Electronic address: george.ibrahim@sickkids.ca.

Publikováno v: Neural networks : the official journal of the International Neural Network Society [Neural Netw] 2023 Oct; Vol. 167, pp. 827-837. Date of Electronic Publication: 2023 Jul 23.

Successful magnetic resonance-guided focused ultrasound treatment of tremor in patients with a skull density ratio of 0.4 or less.

Autor: Vetkas A; 1Department of Surgery, Division of Neurosurgery, University Health Network and University of Toronto., Boutet A; 1Department of Surgery, Division of Neurosurgery, University Health Network and University of Toronto.; 2Joint Department of Medical Imaging, University of Toronto, Ontario, Canada., Sarica C; 1Department of Surgery, Division of Neurosurgery, University Health Network and University of Toronto., Germann J; 1Department of Surgery, Division of Neurosurgery, University Health Network and University of Toronto., Gwun D; 1Department of Surgery, Division of Neurosurgery, University Health Network and University of Toronto., Yamamoto K; 1Department of Surgery, Division of Neurosurgery, University Health Network and University of Toronto., Jung HH; 3Center for Innovative Functional Neurosurgery, Brain Research Institute, Seoul.; 4Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, South Korea., Alkhotani A; 1Department of Surgery, Division of Neurosurgery, University Health Network and University of Toronto., Samuel N; 1Department of Surgery, Division of Neurosurgery, University Health Network and University of Toronto., Lang S; 1Department of Surgery, Division of Neurosurgery, University Health Network and University of Toronto., Conner CR; 1Department of Surgery, Division of Neurosurgery, University Health Network and University of Toronto., Elias GJB; 1Department of Surgery, Division of Neurosurgery, University Health Network and University of Toronto., Cheyuo C; 1Department of Surgery, Division of Neurosurgery, University Health Network and University of Toronto., Chow C; 1Department of Surgery, Division of Neurosurgery, University Health Network and University of Toronto., Santyr B; 1Department of Surgery, Division of Neurosurgery, University Health Network and University of Toronto.; 5Schulich School of Medicine and Dentistry, Western University, London, Ontario., Iorio-Morin C; 6Division of Neurosurgery, CHUS Research Center, University of Sherbrooke, Québec., Yang AZ; 1Department of Surgery, Division of Neurosurgery, University Health Network and University of Toronto., Candeias da Silva C; 1Department of Surgery, Division of Neurosurgery, University Health Network and University of Toronto., Fasano A; 7Edmond J. Safra Program in Parkinson's Disease, Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, University Health Network, Toronto.; 8Department of Medicine, Division of Neurology, University of Toronto.; 9Krembil Research Institute, Toronto.; 10CRANIA, University Health Network and University of Toronto; and.; 11The KITE Research Institute, University Health Network, Toronto, Ontario, Canada., Kalia SK; 1Department of Surgery, Division of Neurosurgery, University Health Network and University of Toronto.; 9Krembil Research Institute, Toronto.; 10CRANIA, University Health Network and University of Toronto; and.; 11The KITE Research Institute, University Health Network, Toronto, Ontario, Canada., Lozano AM; 1Department of Surgery, Division of Neurosurgery, University Health Network and University of Toronto.; 9Krembil Research Institute, Toronto.

Publikováno v: Journal of neurosurgery [J Neurosurg] 2023 Sep 01; Vol. 140 (3), pp. 639-647. Date of Electronic Publication: 2023 Sep 01 (Print Publication: 2024).