Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Elias Einig"'
Autor:
Vanessa Rousseau, Elias Einig, Chao Jin, Julia Horn, Mathias Riebold, Tanja Poth, Mohamed-Ali Jarboui, Michael Flentje, Nikita Popov
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Replicative stress promotes genomic instability and tumorigenesis but also presents an effective therapeutic endpoint, rationalizing detailed analysis of pathways that control DNA replication. We show here that the transcription factor E2f4
Externí odkaz:
https://doaj.org/article/c38108c512d843568839ac3820e48a8c
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Deregulation of RNA Polymerase II (RNAPII) by oncogenic signaling leads to collisions of RNAPII with DNA synthesis machinery (transcription-replication conflicts, TRCs). TRCs can result in DNA damage and are thought to underlie genomic insta
Externí odkaz:
https://doaj.org/article/262e7de7ea85405ea1683eaad570a02b
Autor:
Thaisa Lucas Sandri, Fabiana Antunes Andrade, Kárita Cláudia Freitas Lidani, Elias Einig, Angelica Beate Winter Boldt, Benjamin Mordmüller, Meral Esen, Iara J Messias-Reason
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 4, p e0007324 (2019)
Chagas Disease (CD) is an anthropozoonosis caused by Trypanosoma cruzi. With complex pathophysiology and variable clinical presentation, CD outcome can be influenced by parasite persistence and the host immune response. Complement activation is one o
Externí odkaz:
https://doaj.org/article/26c409f5075e409f80a816c0a9454564
Autor:
Carina R. Maier, Oliver Hartmann, Cristian Prieto-Garcia, Kamal M. Al-Shami, Lisa Schlicker, Felix C. E. Vogel, Silke Haid, Kevin Klann, Viktoria Buck, Christian Münch, Werner Schmitz, Elias Einig, Bastian Krenz, Marco A. Calzado, Martin Eilers, Nikita Popov, Mathias T. Rosenfeldt, Markus E. Diefenbacher, Almut Schulze
Publikováno v:
Cell Death & Differentiation.
SREBP2 is a master regulator of the mevalonate pathway (MVP), a biosynthetic process that drives the synthesis of dolichol, heme A, ubiquinone and cholesterol and also provides substrates for protein prenylation. Here, we identify SREBP2 as a novel s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::daa7350dfb4e409ead8c22bfc7313fb8
https://doi.org/10.1038/s41418-023-01173-6
https://doi.org/10.1038/s41418-023-01173-6
Autor:
Thales Kronenberger, Antti Poso, Liudmyla Taranets, Nikita Popov, Elias Einig, Daniel Dauch, Jule Harbig, Ramona Rudalska, Michael Forster, Sabrina Klotz, Florian Heinzmann, Werner Schmitz, Wei Cui, Lars Zender, Almut Schulze, Agata Dylawerska, Michael Bitzer, Luana D’Artista, Mathias T. Rosenfeldt, Nisar P. Malek, Marteinn Thor Snaebjornsson, Tae-Won Kang, Bernd J. Pichler, Martina Hinterleitner, Stefan Zwirner, Stefan Laufer
Publikováno v:
Nature cancer. 2(2)
The success of molecular therapies targeting specific metabolic pathways in cancer is often limited by the plasticity and adaptability of metabolic networks. Here we show that pharmacologically induced lipotoxicity represents a promising therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::691090814888ee49a4e7d484d6a305a7
https://pubmed.ncbi.nlm.nih.gov/35122080
https://pubmed.ncbi.nlm.nih.gov/35122080
Autor:
Judith Fliegmann, Marilia Almeida-Trapp, Georg Felix, Elias Einig, Hubert Kalbacher, Lei Wang, Markus Albert, Axel Mithöfer
Publikováno v:
Nature Plants. 4:152-156
The discovery in tomato of systemin, the first plant peptide hormone1,2, was a fundamental change for the concept of plant hormones. Numerous other peptides have since been shown to play regulatory roles in many aspects of the plant life, including g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8573bb80976e8e57cb5a5592a511ad89
https://doi.org/10.1038/s41477-018-0106-0
https://doi.org/10.1038/s41477-018-0106-0
Publikováno v:
Nature Plants. 2
Plants and animals recognize microbial invaders by detecting microbe-associated molecular patterns (MAMPs) by cell surface receptors. Many plant species of the Solanaceae family detect the highly conserved nucleic acid binding motif RNP-1 of bacteria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49717b1fa01664869957cb1f3b444fe6
https://doi.org/10.1038/nplants.2016.185
https://doi.org/10.1038/nplants.2016.185
Publikováno v:
Nature Plants. 3:905-905
In the version of this Article originally published, Fig. 6b, which is composed of individual pictures of six plants, inadvertently and erroneously displayed the same image of one Col-0 wt plant twice. This has been corrected so that Fig. 6b now show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1becd60b84b1e2bbd90c56c044e3077
https://doi.org/10.1038/s41477-017-0044-2
https://doi.org/10.1038/s41477-017-0044-2