Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Elias Begas"'
Autor:
Konstantinos Lafazanis, Elias Begas, Irida Papapostolou, Hermis Iatrou, Nikos Sakellaridis, Dimitrios Vlassopoulos, Konstantinos Dimas
Publikováno v:
Medicina, Vol 60, Iss 6, p 864 (2024)
Background and Objectives: Gemcitabine has been used to treat various solid cancers, including, since 1997, metastatic pancreatic cancer. Here, we developed an HPLC-UV method to determine serum gemcitabine levels and use it in pharmacokinetic studies
Externí odkaz:
https://doaj.org/article/e1a1890c426145a5afcaabbffb9984d8
Autor:
Elias Begas, Maria Bounitsi, Demetrios Kouretas, E. K. Asprodini, Evangelos Kouvaras, T. Kilindris, Konstantinos Makaritsis
Publikováno v:
Food and Chemical Toxicology. 130:32-43
Crocus sativus L., a perennial plant grown mainly around the Mediterranean and Iran, has many medicinal properties including anti-inflammatory, anti-depressive and cancer preventing properties. Aqueous herbal extracts may affect the activity of Phase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3642a74721b8cb6df88a3966d6279cb9
https://doi.org/10.1016/j.fct.2019.05.013
https://doi.org/10.1016/j.fct.2019.05.013
Autor:
Elias Begas, Serkos A. Haroutounian, E. K. Asprodini, Konstantinos M. Kasiotis, Athanasia Tsioutsiouliti, Evangelos Kouvaras, Dimitrios Kouretas
Publikováno v:
Food and Chemical Toxicology. 100:80-89
Peppermint leaves are widely used for the symptomatic treatment of digestive disorders. Previous studies have shown significant effects of its natural products on human enzyme activity; however, there is no study available concerning the effects of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9f0e79a575a5acef47e1ba167588210
https://doi.org/10.1016/j.fct.2016.12.021
https://doi.org/10.1016/j.fct.2016.12.021
Autor:
Vassiliki Tsiokou, E. K. Asprodini, Evangelos Kouvaras, Thomas Kilindris, Demetrios Kouretas, Elias Begas
Publikováno v:
Environmental Research. 182:109074
Xenobiotic metabolism at menopause is an under-investigated topic, albeit women spend one-third of their life in the postmenopausal period. The present study examined the effect of menopause on the in vivo activities of CYP1A2, CYP2A6, xanthine oxida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4e944d819f330017e28014ecf25556e
https://doi.org/10.1016/j.envres.2019.109074
https://doi.org/10.1016/j.envres.2019.109074
Autor:
Thomas Kilindris, E. K. Asprodini, Vassiliki Tsiokou, Evangelos Kouvaras, Maria Samara, Ioannis E. Messinis, Elias Begas
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 368(2)
The purpose of the study was to determine whether the in vivo activities of drug-metabolizing enzymes CYP1A2 and CYP2A6, xanthine oxidase (XO), and N-acetyltransferase-2 (NAT2) vary across the menstrual cycle. Forty-two healthy women were studied at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4aa5687295d8a6859dbca8f0b16c426
https://pubmed.ncbi.nlm.nih.gov/30591530
https://pubmed.ncbi.nlm.nih.gov/30591530
Autor:
E. K. Asprodini, Elias Begas, Demetrios Kouretas, Agoritsa Tsioutsioumi, Evangelos Kouvaras, T. Kilindris
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 122
Sideritis scardica (S. scardica) is an endemic plant of the Balkan Peninsula traditionally used as herbal tea for inflammation and gastric disorders. Aqueous herbal extracts may affect the activity of Phase I and II enzymes involved in xenobiotic met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d47a805139391342a63a2efef2c7139a
https://pubmed.ncbi.nlm.nih.gov/30266316
https://pubmed.ncbi.nlm.nih.gov/30266316
Publikováno v:
Biomedical Chromatography. 29:1657-1663
CYP1A2 is important for metabolizing various clinically used drugs. Phenotyping of CYP1A2 may prove helpful for drug individualization therapy. Several HPLC methods have been developed for quantification of caffeine metabolites in plasma and urine. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00e3cdad6cf45ada6ed56a92f00cbc09
https://doi.org/10.1002/bmc.3475
https://doi.org/10.1002/bmc.3475
Autor:
George Papatsibas, Danai D. Daliani, Elias Begas, Christos N. Papandreou, E. K. Asprodini, Andreas Tsakalof
Publikováno v:
Journal of Chromatographic Science. 52:590-595
Methotrexate (MTX) is a dihydrofolate reductase inhibitor that is used for the treatment of tumors and autoimmune diseases. Several automated binding assays are used in clinical practice and numerous chromatographic methods have been developed toward
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5037b5a3c0cbcaf28f53ef99820c8dd1
https://doi.org/10.1093/chromsci/bmt081
https://doi.org/10.1093/chromsci/bmt081
Autor:
Georgios Emmanouil Vatidis, Evangelos Kouvaras, Efthimios Dardiotis, Elias Begas, E. K. Asprodini, Andreas Tsakalof
Publikováno v:
Biomedical Chromatography. 31:e3950
Licarbazepine is the pharmacologically active metabolite of oxcarbazepine, a drug indicated for the treatment of partial seizures and bipolar disorders. Several HPLC methods have been developed thus far but there is lack of control for interferences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::328213092563ab9fc57336c7b830e7bd
https://doi.org/10.1002/bmc.3950
https://doi.org/10.1002/bmc.3950
Autor:
Elias, Begas, Evangelos, Kouvaras, Andreas K, Tsakalof, Maria, Bounitsi, Eftihia Konstadinos, Asprodini
Publikováno v:
Biomedical chromatography : BMC. 29(11)
CYP1A2 is important for metabolizing various clinically used drugs. Phenotyping of CYP1A2 may prove helpful for drug individualization therapy. Several HPLC methods have been developed for quantification of caffeine metabolites in plasma and urine. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::142bde500dd41aa76a30eafa912369ab
https://pubmed.ncbi.nlm.nih.gov/25891161
https://pubmed.ncbi.nlm.nih.gov/25891161