Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Elias B, Nascimento"'
Autor:
Thiago Roberto Lima Romero, Igor D.G. Duarte, Márcio M. Coelho, Marcela M.G.B. Dutra, Bernd L. Fiebich, Elias B. Nascimento
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 135, Iss, Pp 111210-(2021)
Serotonin (5-HT) acts as a neurotransmitter in the central nervous system (CNS) and as a mediator released by enterochromaffin cells to regulate intestinal motility. However, this amine also plays an important role as an inflammatory mediator and ind
Autor:
Elias B, Nascimento, Thiago R L, Romero, Marcela M G B, Dutra, Bernd L, Fiebich, Igor D G, Duarte, Márcio M, Coelho
Publikováno v:
Biomedicinepharmacotherapy = Biomedecinepharmacotherapie. 135
Serotonin (5-HT) acts as a neurotransmitter in the central nervous system (CNS) and as a mediator released by enterochromaffin cells to regulate intestinal motility. However, this amine also plays an important role as an inflammatory mediator and ind
Autor:
Débora P. Araújo, Leandro F.S. Bastos, João Gabriel T. Seniuk, Elias B. Nascimento, Isabela Costa César, Renes R. Machado, Gerson Antônio Pianetti, Raquel R. Menezes, Márcio M. Coelho, Adriana M. Godin, Wallace C. Ferreira, Darly G. Soares, Ângelo de Fátima, Marcela M.G.B. Dutra
Publikováno v:
Pharmacology Biochemistry and Behavior. 106:85-90
Nicorandil (2-nicotinamide ethyl nitrate), an antianginal drug characterized by the coupling of nicotinamide with a nitric oxide (NO) donor, activates guanylyl cyclase and opens ATP-dependent K(+) channels. In the present study, we investigated the e
Autor:
Márcio M. Coelho, Elias B. Nascimento, Leandro F.S. Bastos, Wallace C. Ferreira, Leonardo Tadeu S. Rocha, André Luiz L. Paiva, Adriana M. Godin, João Gabriel T. Seniuk, Leonardo A. Merlo
Publikováno v:
Pharmacology Biochemistry and Behavior. 99(4):782-788
Although there is evidence for the anti-inflammatory activity of nicotinamide, there is no evaluation of its effects in models of nociceptive and inflammatory pain. In addition, there is no information about the potential anti-inflammatory and antino
Autor:
A G R Solano, M C Vilaça, Leonardo A. Merlo, Márcio M. Coelho, Suwatchai Jarussophon, Leandro F.S. Bastos, Leonardo Tadeu S. Rocha, Elzíria de Aguiar Nunan, Adriana M. Godin, Elias B. Nascimento, Yasuo Konishi, A Angusti
Publikováno v:
British Journal of Pharmacology. 155:714-721
Background and purpose: Many in vitro and fewer in vivo studies have shown that tetracyclines present anti-inflammatory activity. We investigated if a novel non-antibacterial, non-chelating hydroxypyrazoline derivative of minocycline, 12S-hydroxy-1,1
Autor:
Antônio Carlos Pinheiro de Oliveira, Karina A. Costa, Elias B. Nascimento, Leonardo Tadeu S. Rocha, Márcio M. Coelho, Caryne M. Bertollo
Publikováno v:
European Journal of Pharmacology. 547:184-191
Riboflavin, similar to other vitamins of the B complex, presents anti-inflammatory activity but its full characterization has not yet been carried out. Therefore, we aimed to investigate the effect of this vitamin in different models of nociception,
Autor:
Antônio Carlos Pinheiro de Oliveira, Márcio M. Coelho, Karina A. Costa, Elias B. Nascimento, Leonardo Tadeu S. Rocha, Caryne M. Bertollo, Adriano L.S. Souza, Tasso Moraes-Santos, Maria Beatriz Abreu Glória
Publikováno v:
Toxicon. 45:585-593
In this study we characterized the nociceptive response and edema induced by the venom of the scorpion Tityus serrulatus in rats and mice and carried out a preliminary pharmacological investigation of the mechanisms involved in these responses. Intra
Autor:
Elias B. Nascimento, Leonardo A. Merlo, Márcio M. Coelho, André Luiz L. Paiva, Leonardo Tadeu S. Rocha, Leandro F.S. Bastos, Adriana M. Godin, Raphael G. Ferreira, Wallace C. Ferreira
Publikováno v:
Pharmacology, biochemistry, and behavior. 101(3)
Although in vitro studies have shown that nicotinic acid inhibits some aspects of the inflammatory response, a reduced number of in vivo studies have investigated this activity. To the best of our knowledge, the effects induced by nicotinic acid in m
Autor:
Elias B. Nascimento, Márcio M. Coelho, Leonardo Tadeu S. Rocha, Antônio A.C. Zumpano, Luiz Guilherme Dias Heneine, Leandro F.S. Bastos, André Luiz L. Paiva, Tasso Moraes-Santos, Adriana M. Godin, Esther Margarida Alves Ferreira Bastos, Leonardo A. Merlo
Publikováno v:
Toxicon : official journal of the International Society on Toxinology. 57(5)
The effects induced by Apis mellifera venom (AMV), melittin-free AMV, fraction with molecular mass F ) or melittin in nociceptive and inflammatory pain models in mice were investigated. Subcutaneous administration of AMV (2, 4 or 6 mg/kg) or melittin
Autor:
Caryne M. Bertollo, Karina A. Costa, Márcio M. Coelho, Elias B. Nascimento, Leonardo Tadeu S. Rocha, Antônio Carlos Pinheiro de Oliveira
Publikováno v:
European journal of pharmacology. 561(1-3)
Peroxisome proliferator activated receptors (PPAR) are ligand-regulated transcription factors that control the expression of many genes. The antiinflammatory activity of fibrates, PPARalpha agonists, and thiazolidinediones, PPARgamma agonists, has be